Associate Professor of Pathology and International Health
Internal Medicine
Dr. Amy G. Hise, MD
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Hise works in the field of Internal Medicine. She attended George Washington University School of Medicine. George Washington University School of Medicine is ranked 67/0 in Research/PrimaryCare. She over the years received 1 awards: "Vice President". Hise is also a published MD. She has 37 paper published. The most recent paper is: T cell-intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis.
Publications
- Association of symptoms and severity of rift valley Fever with genetic polymorphisms in human innate immune pathways.
- Factors associated with severe human rift valley Fever in sangailu, garissa county, kenya.
- Inflammasomes in aspergillosis-it takes two to tango.
- β-Defensin 1 plays a role in acute mucosal defense against Candida albicans.
- Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.
- A Role for the Adaptor Proteins TRAM and TRIF in Toll-Like Receptor 2 Signaling.
- Caspase-8 Modulates Dectin-1 and Complement Receptor 3-Driven IL-1β Production in Response to β-Glucans and the Fungal Pathogen, Candida albicans.
- Rift Valley fever virus infection induces activation of the NLRP3 inflammasome.
- Reduced frequency of a CD14+ CD16+ monocyte subset with high Toll-like receptor 4 expression in cord blood compared to adult blood contributes to lipopolysaccharide hy...
- RNA helicase signaling is critical for type I interferon production and protection against Rift Valley fever virus during mucosal challenge.
- Host defense at the ocular surface.
- Ocular manifestations of the autoinflammatory syndromes.
- Cutting edge: IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and caspase-1.
- A Novel Role for the NLRC4 Inflammasome in Mucosal Defenses against the Fungal Pathogen Candida albicans.
- Arbovirus prevalence in mosquitoes, Kenya.
- Bacterial pathogen-associated molecular patterns stimulate biological activity of orthopaedic wear particles by activating cognate Toll-like receptors.
- CD14 and toll-like receptors 2 and 4 are required for fibrillar A{beta}-stimulated microglial activation.
- An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.
- An early complement-dependent and TLR-4-independent phase in the pathogenesis of ethanol-induced liver injury in mice.
- TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
- Toll-like receptor 2 regulates CXC chemokine production and neutrophil recruitment to the cornea in Onchocerca volvulus/Wolbachia-induced keratitis.
- Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, o...
- Staphylococcus aureus-induced corneal inflammation is dependent on Toll-like receptor 2 and myeloid differentiation factor 88.
- Wolbachia- and Onchocerca volvulus-induced keratitis (river blindness) is dependent on myeloid differentiation factor 88.
- Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation.
- Wolbachia-induced neutrophil activation in a mouse model of ocular onchocerciasis (river blindness).
- Bactericidal activity in whole blood as a potential surrogate marker of immunity after vaccination against tuberculosis.
- The role of endosymbiotic Wolbachia bacteria in the pathogenesis of river blindness.
- Alcohol-induced liver injury is modulated by Nlrp3 and Nlrc4 inflammasomes in mice.
- The role of endosymbiotic Wolbachia bacteria in filarial disease.
- Polymorphisms of innate immunity genes and susceptibility to lymphatic filariasis.
- Filaria/Wolbachia activation of dendritic cells and development of Th1-associated responses is dependent on Toll-like receptor 2 in a mouse model of ocular onchocercia...
- A whole blood bactericidal assay for tuberculosis.
- Human immunodeficiency virus 1 protease inhibitors in clinical practice: predictors of virological outcome.
- Immunopathogenesis of Onchocerca volvulus keratitis (river blindness): a novel role for TLR4 and endosymbiotic Wolbachia bacteria.
- T cell-intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis.
Schools
George Washington University School of Medicine And Health Sciences
Doctors Specialties
- Internal Medicine
Accepted Insurances
Awards
- Vice President
Education
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Case Western Reserve University - University Hospitals -
George Washington University School of Medicine
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