Physician
Endocrinology
Dr. Arthur E. Broadus, MD
Arthur Broadus practices Endocrinology. He studied medicine at Vanderbilt University School of Medicine. He received 1 awards: "Elected Member". Arthur Broadus is a published doctor. He published 99 publications, including: 'Parathyroid hormone-related protein markedly potentiates depolarization-induced catecholamine release in PC12 cells via L-type voltage-sensitive Ca2+ channels.'
Publications
- Periosteal PTHrP regulates cortical bone modeling during linear growth in mice.
- The remarkable migration of the medial collateral ligament.
- PTHrP regulates the modeling of cortical bone surfaces at fibrous insertion sites during growth.
- Genetic evidence that parathyroid hormone-related protein regulates articular chondrocyte maintenance.
- Regulation of articular chondrocyte proliferation and differentiation by indian hedgehog and parathyroid hormone-related protein in mice.
- Mechanical regulation of PTHrP expression in entheses.
- The PTHrP functional domain is at the gates of endochondral bones.
- Induction of parathyroid hormone-related peptide following peripheral nerve injury: role as a modulator of Schwann cell phenotype.
- Initial characterization of PTH-related protein gene-driven lacZ expression in the mouse.
- Stretch-induced PTH-related protein gene expression in osteoblasts.
- PTHrP regulates cerebral blood flow and is neuroprotective.
- Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 7-2002. A 47-year-old woman with late recurrent hyperparathyroidism.
- Regulation of protein synthesis in heart muscle. I. Effect of amino acid levels on protein synthesis.
- Effect of acute metabolic acidemia on renal electrolyte transport in man.
- The localization of abnormal mediastinal parathyroid glands.
- 1,25(OH)2D3 is not the only D metabolite involved in the pathogenesis of osteomalacia.
- Endogenous parathyroid hormone-related protein functions as a neuroprotective agent.
- Parathyroid hormone-related protein induces spontaneous osteoclast formation via a paracrine cascade.
- Parathyroid hormone-related protein protects against kainic acid excitotoxicity in rat cerebellar granule cells by regulating L-type channel calcium flux.
- Parathyroid hormone-related protein markedly potentiates depolarization-induced catecholamine release in PC12 cells via L-type voltage-sensitive Ca2+ channels.
- PTHrP regulates epidermal differentiation in adult mice.
- Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development.
- Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development.
- Parathyroid hormone-related protein: from hypercalcemia of malignancy to developmental regulatory molecule.
- Parathyroid hormone-related peptide is produced by cultured cerebellar granule cells in response to L-type voltage-sensitive Ca2+ channel flux via a Ca2+/calmodulin-de...
- Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation.
- Parathyroid hormone-related protein gene expression in human squamous carcinoma cells is repressed by mutant isoforms of p53.
- Transactivation of the PTHrP gene in squamous carcinomas predicts the occurrence of hypercalcemia in athymic mice.
- Defining the roles of parathyroid hormone-related protein in normal physiology.
- Overexpression of parathyroid hormone-related protein or parathyroid hormone in transgenic mice impairs branching morphogenesis during mammary gland development.
- Identification and characterization of a GC-rich promoter of the human parathyroid hormone-related peptide gene.
- Calcium and kidney stones.
- Hypercalcemia of malignancy: the central role of parathyroid hormone-related protein.
- Regulation of parathyroid hormone-related peptide gene expression by estrogen in GH4C1 rat pituitary cells has the pattern of a primary response gene.
- Dietary hypercalciuria in patients with calcium oxalate kidney stones.
- Parathyroid hormone-related protein: evidence for isoform- and tissue-specific posttranslational processing.
- Cell type-specific secretion of parathyroid hormone-related protein via the regulated versus the constitutive secretory pathway.
- Region-specific methylation of the parathyroid hormone-related peptide gene determines its expression in human renal carcinoma cell lines.
- Overexpression of parathyroid hormone-related protein in the skin of transgenic mice interferes with hair follicle development.
- Low urine volume in stone formers.
- Diagnostic and therapeutic approaches to primary hyperparathyroidism.
- The importance of circulating 1,25-dihydroxyvitamin D in the pathogenesis of hypercalciuria and renal-stone formation in primary hyperparathyroidism.
- The diagnostic evaluation of risk factors for urinary tract stones: an analysis of care patterns in five hospitals.
- Quantitative bone histomorphometry in humoral hypercalcemia of malignancy: uncoupling of bone cell activity.
- Hypercalcemia associated with gynecologic malignancies: biochemical characterization.
- The regulation of renal calcium excretion: an approach to hypercalciuria.
- PTH-vitamin D interrelationships.
- Nephrolithiasis and hyperparathyroidism.
- Factors associated with humoral hypercalcemia of malignancy stimulate adenylate cyclase in osteoblastic cells.
- The regional educational impact of a Renal Stone Center.
- Oxalate absorption and postprandial urine supersaturation in an experimental human model of absorptive hypercalciuria.
- Biochemical and histomorphometric characterization of a rat model for humoral hypercalcemia of malignancy.
- A consideration of the hormonal basis and phosphate leak hypothesis of absorptive hypercalciuria.
- Hypercalciuria as a metabolic disease.
- Evidence for disordered control of 1,25-dihydroxyvitamin D production in absorptive hypercalciuria.
- An experimental human model of 1,25-dihydroxyvitamin D-mediated hypercalciuria.
- Impaired phosphorus conservation and 1,25 dihydroxyvitamin D generation during phosphorus deprivation in familial hypophosphatemic rickets.
- Primary hyperparathyroidism viewed as a bihormonal disease process.
- A detailed evaluation of oral phosphate therapy in selected patients with primary hyperparathyroidism.
- Identification of adenylate cyclase-stimulating activity and cytochemical glucose-6-phosphate dehydrogenase-stimulating activity in extracts of tumors from patients wi...
- Calcium homeostasis in immobilization: an example of resorptive hypercalciuria.
- Malignancy-associated hypercalcemia: evaluation with a cytochemical bioassay for parathyroid hormone.
- Nephrogenous cyclic AMP.
- Long-term treatment of familial hypophosphatemic rickets with oral phosphate and 1 alpha-hydroxyvitamin D3.
- The influence of calcium intake and the status of intestinal calcium absorption on the diagnostic utility of measurements of 24-hour cyclic adenosine 3',5'-monophospha...
- Clinical evaluation of parathyroid function.
- Biochemical evaluation of patients with cancer-associated hypercalcemia: evidence for humoral and nonhumoral groups.
- Effects of parathyroid hormone on plasma and urinary adenosine 3'',5''-monophosphate in man.
- Effects of glucagon on adenosine 3'',5''-monophosphate and guanosine 3'',5''-monophosphate in human plasma and urine.
- Kinetic parameters and renal clearances of plasma adenosine 3'',5''-monophosphate and guanosine 3'',5''-monophosphate in man.
- Effects of catecholamines and adrenergic-blocking agents on plasma and urinary cyclic nucleotides in man.
- Extracellular cyclic nucleotides.
- Hormonal effects on extracellular cyclic nucleotides in man.
- Analysis of adenosine 3'',5''-monophosphate with luciferase luminescence.
- Messenger ribonucleic acid from tumors associated with humoral hypercalcemia of malignancy directs the synthesis of a secretory parathyroid hormone-like peptide.
- Pregnancy as state of physiologic absorptive hypercalciuria.
- Concerning the pathogenesis of idiopathic hypercalciuria.
- N-terminal amino acid sequence of two novel tumor-derived adenylate cyclase-stimulating proteins: identification of parathyroid hormone-like and parathyroid hormone-un...
- Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy.
- Hypercalcemia of malignancy.
- Co-purification of transforming growth factor beta-like activity with PTH-like and bone-resorbing activities from a tumor associated with humoral hypercalcemia of mali...
- Two forms of parathyroid hormone-like adenylate cyclase-stimulating protein derived from tumors associated with humoral hypercalcemia of malignancy.
- The relative potency of a human tumor-derived PTH-like adenylate cyclase-stimulating preparation in three bioassays.
- Influence of furosemide on parathyroid hormone levels in hyperparathyroidism.
- In vitro adenylate cyclase-stimulating activity predicts the occurrence of humoral hypercalcemia of malignancy in nude mice.
- Synthetic human parathyroid hormone-like protein stimulates bone resorption and causes hypercalcemia in rats.
- Synthetic and partially-purified adenylate cyclase-stimulating proteins from tumors associated with humoral hypercalcemia of malignancy inhibit phosphate transport in ...
- Enhanced production rate of 1,25-dihydroxyvitamin D in sarcoidosis.
- Expression of messenger ribonucleic acids encoding a parathyroid hormone-like peptide in normal human and animal tissues with abnormal expression in human parathyroid ...
- Humoral hypercalcemia of cancer. Identification of a novel parathyroid hormone-like peptide.
- Nephrogenous cyclic AMP, adenylate cyclase-stimulating activity, and the humoral hypercalcemia of malignancy.
- Two species of adenylate cyclase-stimulating activity in a murine squamous carcinoma model of humoral hypercalcemia of malignancy.
- Sensitivity of the parathyroid hormone-1,25-dihydroxyvitamin D axis to variations in calcium intake in patients with primary hyperparathyroidism.
- Elevated production rate of 1,25-dihydroxyvitamin D in patients with absorptive hypercalciuria.
- Isolation and characterization of the human parathyroid hormone-like peptide gene.
- Trichlormethiazide and oral phosphate therapy in patients with absorptive hypercalciuria.
- Frequency and partial characterization of adenylate cyclase-stimulating activity in tumors associated with humoral hypercalcemia of malignancy.
- Humoral hypercalcemia of malignancy in canine lymphosarcoma.
Schools
Vanderbilt University
Massachusetts General Hospital
National Institute Of Health
Doctors Specialties
- Internal Medicine
- Endocrinology
Accepted Insurances
Awards
- Elected Member
Education
-
Massachusetts General Hospital -
Vanderbilt University School of Medicine
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