Professor, Pediatrics, LSU School of Medicine New Orleans
Allergy & Immunology
Dr. Augusto C. Ochoa, MD
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Augusto Ochoa is an expert in the field of Allergy & Immunology. He over the years received 2 awards: "Super Doctor" and "Fellow (FAAP)". Augusto Ochoa is a published physician as well. He has 100 publications published. The latest was: Expression of prolactin mRNA and of prolactin-like proteins in endothelial cells: evidence for autocrine effects.
Publications
- Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies.
- TLR5 ligand-secreting T cells reshape the tumor microenvironment and enhance antitumor activity.
- L-Arginine depletion blunts anti-tumor T cell responses by inducing myeloid-derived suppressor cells.
- Molecular Mechanisms of Fenofibrate-Induced Metabolic Catastrophe and Glioblastoma Cell Death.
- The stress-response sensor chop regulates the function and accumulation of myeloid-derived suppressor cells in tumors.
- Arginase I levels are decreased in the plasma of pediatric patients with Atopic dermatitis.
- Rescue of Notch 1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T cell suppression and enhances immunotherapy in cancer.
- Polycyclic aromatic hydrocarbons-induced ROS accumulation enhances mutagenic potential of T-antigen from human polyomavirus JC.
- Subpopulations of Myeloid-Derived Suppressor Cells (MDSC) impair T cell responses through independent nitric oxide-related pathways.
- The antimicrobial agent C31G is Effective for therapy for HSV-1 ocular keratitis in the rabbit eye model.
- Trp53 inactivation in the tumor microenvironment promotes tumor progression by expanding the immunosuppressive lymphoid-like stromal network.
- Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4.
- Inhibition of ERβ induces resistance to cisplatin by enhancing Rad51-mediated DNA repair in human medulloblastoma cell lines.
- Association of haplotypes of inflammation-related genes with gastric preneoplastic lesions in African Americans and Caucasians.
- Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin...
- L-arginine deprivation regulates cyclin D3 mRNA stability in human T cells by controlling HuR expression.
- Requirement for inducible nitric oxide synthase in Chronic allergen exposure-induced pulmonary fibrosis but not inflammation.
- Tumor-infiltrating regulatory dendritic cells inhibit CD8+ T cell function via L-arginine metabolism.
- Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes.
- L-arginine availability regulates T-lymphocyte cell-cycle progression.
- Innovations and challenges in renal cell carcinoma: summary statement from the Second Cambridge Conference.
- Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma.
- Decreased expression of CD3zeta and nuclear transcription factor kappa B in patients with pulmonary tuberculosis: potential mechanisms and reversibility with treatment.
- In vitro and in vivo complementation of the Helicobacter pylori arginase mutant using an intergenic chromosomal site.
- Association of interleukin-1beta gene polymorphisms with precancerous gastric lesions in African Americans and Caucasians.
- Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma.
- Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response.
- Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion.
- Mechanisms of tumor evasion.
- L-Arginine modulates CD3zeta expression and T cell function in activated human T lymphocytes.
- Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses.
- Decreased expression of T-cell NF-kappaB p65 subunit in steroid-resistant nephrotic syndrome.
- Helicobacter pylori arginase inhibits T cell proliferation and reduces the expression of the TCR zeta-chain (CD3zeta).
- L-arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes.
- Regulation of T cell receptor CD3zeta chain expression by L-arginine.
- Inhibition of rat corneal angiogenesis by 16-kDa prolactin and by endogenous prolactin-like molecules.
- Herpes simplex virus-infected cells disarm killer lymphocytes.
- Expression of human apolipoprotein A-I/C-III/A-IV gene cluster in mice induces hyperlipidemia but reduces atherogenesis.
- Establishment of a leukemic cell line MT-ALL with multilineage differentiation potential.
- Human apolipoprotein A-IV gene expression is modulated by members of the nuclear hormone receptor superfamily.
- Transcriptional regulation of 5-aminolevulinate synthase by phenobarbital and cAMP-dependent protein kinase.
- Human apolipoprotein A-IV reduces gastric acid secretion and diminishes ulcer formation in transgenic mice.
- Alpha-difluoromethylornithine-resistant cell lines obtained after one-step selection of Leishmania mexicana promastigote cultures.
- Fenofibric acid modulates the human apolipoprotein A-IV gene expression in HepG2 cells.
- [The treatment and prognosis of sarcoidosis. Apropos 53].
- The growth of cells with LAK activity in an automated tissue culture system (Acusyst P).
- Long-term culture of LAK cells: expansion and activation signals.
- Lymphokine activated killer (LAK) cell-mediated endothelial injury: a mechanism for capillary leak syndrome in patients treated with LAK cells and interleukin-2.
- Somatostatin as a mediator of the Effect of neurotensin on pentagastrin-stimulated acid secretion in rats.
- Loss and re-acquisition of lytic function by cloned cytoToxic T lymphocytes: role of specific antigen and interleukin 2.
- Long-term growth of lymphokine-activated killer (LAK) cells: role of anti-CD3, beta-IL 1, interferon-gamma and -beta.
- Treatment of cancer patients with ex vivo anti-CD3-activated killer cells and interleukin-2.
- Lymphokine-activated killer (LAK) cells can be focused at sites of tumor growth by products of macrophage activation.
- Antioxidative and antiatherosclerotic Effects of human apolipoprotein A-IV in apolipoprotein E-deficient mice.
- Expression of prolactin gene and secretion of prolactin by rat retinal capillary endothelial cells.
- The apolipoprotein A-I/C-III/A-IV gene cluster: ApoC-III and ApoA-IV expression is regulated by two common enhancers.
- Increased circulating nitrogen oxides after human tumor immunotherapy: correlation with Toxic hemodynamic changes.
- Expression of human apolipoprotein A-I/C-III/A-IV gene cluster in mice reduces atherogenesis in response to a high fat-high cholesterol diet.
- Interactions of DNA-binding proteins with the 5' region of the human transferrin gene.
- Anti-tumor vaccine adjuvant Effects of IL-2 liposomes in mice immunized against MCA-102 sarcoma.
- Depot characteristics and biodistribution of interleukin-2 liposomes: importance of route of administration.
- Identification of an enhancer involved in the melanoma-specific expression of the tumor antigen melanotransferrin gene.
- Human alloreactive CTL clones: loss and reacquisition of specific cytolytic activity can be regulated by "recombinant" interleukin 2.
- Expression of prolactin mRNA and of prolactin-like proteins in endothelial cells: evidence for autocrine Effects.
- Mechanism of cultured endothelial injury induced by lymphokine-activated killer cells.
- Alteration of signal transduction in T cells from cancer patients.
- Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice.
- Influence of interleukin-2 regimens on circulating populations of lymphocytes after adoptive transfer of anti-CD3-stimulated T cells: results from a phase I trial in c...
- Gradual loss of T-helper 1 populations in spleen of mice during progressive tumor growth.
- Cytokines in liposomes: preliminary studies with IL-1, IL-2, IL-6, GM-CSF and interferon-gamma.
- Decreased expression of signal-transducing CD3 zeta chains in T cells from the joints and peripheral blood of rheumatoid arthritis patients.
- Lepromatous and tuberculoid leprosy: clinical presentation and cytokine responses.
- Increased local antitumor Effects of interleukin 2 liposomes in mice with MCA-106 sarcoma pulmonary metastases.
- Anti-CD3 + interleukin-2 stimulation of marrow and blood: comparison of proliferation and cytoToxicity.
- Mature T-lineage leukemia with growth factor-induced multilineage differentiation.
- Sequential development of structural and functional alterations in T cells from tumor-bearing mice.
- Enhanced lymphokine production and lymphokine receptor expression in multiple antibody-stimulated human CD4+ peripheral blood lymphocytes.
- Liposomal formulation of a self lymphoma antigen induces potent protective antitumor immunity.
- Antitumor Effects of interleukin 2 liposomes and anti-CD3-stimulated T-cells against murine MCA-38 hepatic metastasis.
- Lymphokine-activated killer activity in long-term cultures with anti-CD3 plus interleukin 2: identification and isolation of Effector subsets.
- Importance in timing of cyclophosphamide on the enhancement of interleukin-2-induced cytolysis.
- Phase I trial of anti-CD3-stimulated CD4+ T cells, infusional interleukin-2, and cyclophosphamide in patients with advanced cancer.
- Short-term ex vivo activation of splenocytes with anti-CD3 plus IL-2 and infusion post-BMT into mice results in in vivo expansion of Effector cells with potent anti-ly...
- The terminology issue for myeloid-derived suppressor cells.
- A phase I randomized study of subcutaneous adjuvant IL-2 in combination with an autologous tumor vaccine in patients with advanced renal cell carcinoma.
- B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma.
- Primary chemically induced tumors induce profound immunosuppression concomitant with apoptosis and alterations in signal transduction in T cells and NK cells.
- Where have all the T cells gone? Mechanisms of immune evasion by tumors.
- Generation of lymphokine-activated killer activity in T cells. Possible regulatory circuits.
- Adoptive transfer of anti-CD3-activated CD4+ T cells plus cyclophosphamide and liposome-encapsulated interleukin-2 cure murine MC-38 and 3LL tumors and establish tumor...
- Regulation of lymphokine-activated killer activity and pore-forming protein gene expression in human peripheral blood CD8+ T lymphocytes. Inhibition by transforming gr...
- Proliferation and cytolytic function of anti-CD3 + interleukin-2 stimulated peripheral blood mononuclear cells following bone marrow transplantation.
- Augmentation of cell number and LAK activity in peripheral blood mononuclear cells activated with anti-CD3 and interleukin-2. Preliminary results in children with acut...
- Anti-CD3 + IL-2-stimulated murine killer cells. In vitro generation and in vivo antitumor activity.
- Changes in expression of signal transduction proteins in T lymphocytes of patients with leprosy.
- L-Arginine regulates the expression of the T-cell receptor zeta chain (CD3zeta) in Jurkat cells.
- Restoration of expression of signal-transduction molecules in lymphocytes from patients with metastatic renal cell cancer after combination immunotherapy.
- Partial degradation of T-cell signal transduction molecules by contaminating granulocytes during protein extraction of splenic T cells from tumor-bearing mice.
- Mechanisms of tumor evasion from the immune response.
Procedures Preformed
- Allergy Skin Testing
Conditions Treated
- Allergic Rhinitis
- Angioedema
- Asthma
- Atopic Dermatitis (Eczema)
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Doctors Specialties
- Allergy
- Immunology
Accepted Insurances
Awards
- Super Doctor
- Fellow (FAAP)
Education
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Louisiana State University
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