Professor, Pediatrics, Medical College of Georgia at Georgia Health Sciences University
Pediatric Hematology & Oncology
Dr. Betty S. Pace, MD
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Betty Pace practices Pediatric Hematology & Oncology. She attended Medical College of Wisconsin Affiliated Hospitals. Betty Pace is also published. She has 52 publications published. The lastest publication: "Abrogation of IL-3 requirements and stimulation of hematopoietic cell proliferation in vitro and in vivo by carboxylic acids.'
Publications
- UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development.
- Monomethylfumarate Induces Fetal Hemoglobin Production in Cultured Human Retinal Pigment Epithelial (RPE) and Erythroid Cells, and in Intact Retina.
- Targeted Fetal Hemoglobin Induction for Treatment of Beta Hemoglobinopathies.
- Sickle cell disease: genetics, cellular and molecular mechanisms, and therapies.
- FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors.
- Krüppel-like Factor 4 activates HBG gene expression in primary erythroid cells.
- Regulation of γ-globin gene expression involves signaling through the p38 MAPK/CREB1 pathway.
- Histone deacetylase 9 activates gamma-globin gene expression in primary erythroid cells.
- The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice.
- cJun modulates Ggamma-globin gene expression via an upstream cAMP response element.
- Hydroxyurea generates nitric oxide in human erythroid cells: mechanisms for gamma-globin gene activation.
- High-density SNP genotyping to define beta-globin locus haplotypes.
- Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves gamma-globin activation by CREB1 and ATF-2.
- Understanding mechanisms of gamma-globin gene regulation to develop strategies for pharmacological fetal hemoglobin induction.
- Effects of N-acetylcysteine on dense cell formation in sickle cell disease.
- Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo.
- HIV-1 Tat protein-mediated transactivation of the HIV-1 long terminal repeat promoter is potentiated by a novel nuclear Tat-interacting protein of 110 kDa, Tip110.
- Stat3 beta inhibits gamma-globin gene expression in erythroid cells.
- Fetal hemoglobin induction by histone deacetylase inhibitors involves generation of reactive oxygen species.
- Role of STAT3 and GATA-1 interactions in gamma-globin gene expression.
- p38 MAP kinase activation mediates gamma-globin gene induction in erythroid progenitors.
- Zileuton induces hemoglobin F synthesis in erythroid progenitors: role of the L-arginine-nitric oxide signaling pathway.
- BFU-E colony growth in response to hydroxyurea: correlation between in vitro and in vivo fetal hemoglobin induction.
- Mechanism for fetal hemoglobin induction by hydroxyurea in sickle cell erythroid progenitors.
- Short-chain fatty acid derivatives stimulate cell proliferation and induce STAT-5 activation.
- Identification of fetal hemoglobin-inducing agents using the human leukemia KU812 cell line.
- Butyrate-inducible elements in the human gamma-globin promoter.
- Erk pathway inhibitor U0126 induces gamma-globin expression in erythroid cells.
- Fetal hemoglobin induction by acetate, a product of butyrate catabolism.
- Abrogation of IL-3 requirements and stimulation of hematopoietic cell proliferation in vitro and in vivo by carboxylic acids.
- Peptide nucleic acid (PNA) binding-mediated induction of human gamma-globin gene expression.
- Globin gene silencing in primary erythroid cultures. An inhibitory role for interleukin-6.
- In vivo search for butyrate responsive sequences using transgenic mice carrying A gamma gene promoter mutants.
- Fetal hemoglobin induction by the histone deacetylase inhibitor, scriptaid.
- Pharmacologic induction of fetal hemoglobin synthesis: cellular and molecular mechanisms.
- Beta globin gene inhibition by antisense RNA transcripts.
- Selective inhibition of beta-globin RNA transcripts by antisense RNA molecules.
- alpha-Amino butyric acid cannot reactivate the silenced gamma gene of the beta locus YAC transgenic mouse.
- Transgenic mouse model of pharmacologic induction of fetal hemoglobin: studies using a new ribonucleotide reductase inhibitor, Didox.
- Sickle cell disease summit: from clinical and research disparity to action.
- Partial purification and properties of a ribosomal RNA maturation endonuclease from Bacillus subtilis.
- Characterization of ribonuclease P from the archaebacterium Sulfolobus solfataricus.
- The RNA component of the Bacillus subtilis RNase P. Sequence, activity, and partial secondary structure.
- The conserved 5 S rRNA complement to tRNA is not required for translation of natural mRNA.
- A cell-based high-throughput screen for novel chemical inducers of fetal hemoglobin for treatment of hemoglobinopathies.
- The ribonucleoprotein substrate for a ribosomal RNA-processing nuclease.
- Ethanol Exposure Induces Neonatal Neurodegeneration by Enhancing CB1R Exon1 Histone H4K8 Acetylation and Up-regulating CB1R Function causing Neurobehavioral Abnormalit...
- The catalytic element of a ribosomal RNA-processing complex.
- Regulation of Gγ-Globin Gene by ATF2 and Its Associated Proteins through the cAMP-Response Element.
- Enhancing the Careers of Under-Represented Junior Faculty in Biomedical Research: The Summer Institute Program to Increase Diversity (SIPID).
- Characterization of Transcription Factor Networks Involved in Umbilical Cord Blood CD34+ Stem Cells-Derived Erythropoiesis.
Schools
Med Coll Of Wi
Chldns Hospital Wisc
University Of Colorado
Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Education
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Medical College of Wisconsin Affiliated Hospitals
Hospital
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Georgia Regents Medical Center
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