Assistant Professor, Surgery, University of Connecticut SOM
General Surgery
Dr. Brian D. Shames, MD
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Doctor Brian D. Shames, MD practices General Surgery. He went to medical school at University of Connecticut School of Medicine. University of Connecticut School of Medicine is ranked 60 in research and 49 in primary care medicine He received awards:"CMS Meaningful Use Stage 1 Certification" and "Fellow". Brian Shames is also published. He has 80 publications published. The lastest publication: "Interleukin-10 inhibits postinjury tumor necrosis factor-mediated human vascular smooth muscle proliferation.' He accepts Medicare payments and is registered with Medicare.gov.
Publications
- Chromosome substitution modulates resistance to ischemia reperfusion injury in Brown Norway rats.
- Protective effect of Lifor solution in experimental renal ischemia-reperfusion injury.
- Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury.
- Oxidant-mediated apoptosis in proximal tubular epithelial cells following ATP depletion and recovery.
- Simultaneous pancreas-kidney transplantation from donation after cardiac death: successful long-term outcomes.
- Donation after cardiac death: the University of Wisconsin experience with Liver transplantation.
- Liver transplantation for HELLP syndrome.
- Surgical repair of transplant renal artery Stenosis with preserved cadaveric iliac artery grafts.
- Ischemia alone is sufficient to induce TNF-alpha mRNA and peptide in the myocardium.
- Expression of epsilon BP, a beta-galactoside-binding soluble lectin, in normal and neoplastic epidermis.
- Intracellular Campylobacter-like organism from ferrets and hamsters with proliferative bowel Disease is a Desulfovibrio sp.
- Long-term colonization with single and multiple strains of Helicobacter pylori assessed by DNA fingerprinting.
- Helicobacter pylori-induced gastritis in the domestic cat.
- Evaluation of antibiotic therapies for eradication of Helicobacter hepaticus.
- Helicobacter bilis sp. nov., a novel Helicobacter species isolated from bile, Livers, and intestines of aged, inbred mice.
- Typing of Campylobacter pylori by bacterial DNA restriction endonuclease analysis and determination of plasmid profile.
- Antigenic shifts in serotype determinants of Campylobacter coli are accompanied by changes in the chromosomal DNA restriction endonuclease digestion pattern.
- Omeprazole therapy for Helicobacter pylori infection.
- Variation of the O antigen of Campylobacter jejuni in vivo.
- Natural and experimental Helicobacter mustelae reinfection following successful antimicrobial eradication in ferrets.
- Helicobacter rodentium sp. nov., a urease-negative Helicobacter species isolated from laboratory mice.
- Proliferative enteropathy of rabbits: the intracellular Campylobacter-like organism is closely related to Lawsonia intracellularis.
- Persistent hepatitis and enterocolitis in germfree mice infected with Helicobacter hepaticus.
- Evaluation of various oral antimicrobial formulations for eradication of Helicobacter hepaticus.
- Identification of widespread Helicobacter hepaticus infection in feces in commercial mouse colonies by culture and PCR assay.
- The role of calcium in the Chlamydomonas reinhardtii mating reaction.
- Role of gastric pH in isolation of Helicobacter mustelae from the feces of ferrets.
- SCID/NCr mice naturally infected with Helicobacter hepaticus develop progressive hepatitis, proliferative typhlitis, and colitis.
- Spontaneous inflammatory bowel Disease in multiple mutant mouse lines: association with colonization by Helicobacter hepaticus.
- Postinjury suppression of human neutrophil cytokine production results from the stabilization of inhibitory kappaB.
- Interleukin-10 inhibits postinjury tumor necrosis factor-mediated human Vascular smooth muscle proliferation.
- Interleukin-10 stabilizes inhibitory kappaB-alpha in human monocytes.
- Ischemic preconditioning decreases postischemic myocardial tumor necrosis factor-alpha production. Potential ultimate effector mechanism of preconditioning.
- Therapeutic implications of interleukin-10 in surgical Disease.
- Interleukin-10 inhibits human Vascular smooth muscle proliferation.
- Calcium preconditioning in human myocardium.
- The biology of estrogen-mediated repair of cardioVascular injury.
- Human myocardial tissue TNFalpha expression following acute global ischemia in vivo.
- Nitric oxide downregulates Lung macrophage inflammatory cytokine production.
- Increased levels of myocardial IkappaB-alpha protein promote tolerance to endotoxin.
- Class II cytokine receptor ligands inhibit human Vascular smooth muscle proliferation.
- Hydrogen peroxide induces tumor necrosis factor alpha-mediated cardiac injury by a P38 mitogen-activated protein kinase-dependent mechanism.
- TNF-alpha and myocardial depression in endotoxemic rats: temporal discordance of an obligatory relationship.
- Genes don't count.
- Reactivity of cysteine residues in the protease from human immunodeficiency virus: identification of a surface-exposed region which affects enzyme function.
- Inhibition of cyclic-3',5'-nucleotide phosphodiesterase abrogates the synergism of hypoxia with lipopolysaccharide in the induction of macrophage TNF-alpha production.
- Suppression of tumor necrosis factor alpha production by cAMP in human monocytes: dissociation with mRNA level and independent of interleukin-10.
- Differential cellular immunolocalization of renal tumour necrosis factor-alpha production during ischaemia versus endotoxaemia.
- L-arginine attenuates lipopolysaccharide-induced Lung chemokine production.
- Thirty years of clinical trials in acute respiratory distress syndrome.
- Chemokines as mediators of Diseases related to surgical conditions.
- Differential inducible nitric oxide synthase expression in systemic and pulmonary vessels after endotoxin.
- Adenosine preconditioning reduces both pre and postischemic arrhythmias in human myocardium.
- Chlamydia pneumoniae activates nuclear factor kappaB and activator protein 1 in human Vascular smooth muscle and induces cellular proliferation.
- Stimulated apoptosis as an anti-neoplastic strategy.
- Interleukin-1beta deficiency results in reduced NF-kappaB levels in pregnant mice.
- Exogenous calcium preconditions myocardium from patients taking oral sulfonylurea agents.
- Inhibition of PARS attenuates endotoxin-induced dysfunction of pulmonary vasorelaxation.
- Reduction of infarct size in the rat heart by LPS preconditioning is associated with expression of angiogenic growth factors and increased capillary density.
- Liposomal deLivery of heat-shock protein 72 into the heart prevents endotoxin-induced myocardial contractile dysfunction.
- Inhibition of myocardial TNF-alpha production by heat shock. A potential mechanism of stress-induced cardioprotection against postischemic dysfunction.
- Calcium preconditioning, but not ischemic preconditioning, bypasses the adenosine triphosphate-dependent potassium (KATP) channel.
- Review article: the role of tumor necrosis factor in renal ischemia-reperfusion injury.
- Cardiotrophin-1 attenuates endotoxin-induced acute Lung injury.
- The NFkappaB inhibitory peptide, IkappaBalpha, prevents human Vascular smooth muscle proliferation.
- Adrenergic induction of bimodal myocardial protection: signal transduction and cardiac gene reprogramming.
- Liposomal deLivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation.
- LPS-Induced NF-kappaB activation and TNF-alpha release in human monocytes are protein tyrosine kinase dependent and protein kinase C independent.
- p38 MAPK inhibition decreases TNF-alpha production and enhances postischemic human myocardial function.
- Utilization of endoscopic inoculation in a mouse model of intrauterine infection-induced preterm birth: role of interleukin 1beta.
- Living-unrelated renal transplantation at the University of Wisconsin.
- Does opening the peritoneum at the time of renal transplanation prevent lymphocele formation?
- MnTMPyP, a superoxide dismutase/catalase mimetic, decreases inflammatory indices in ischemic acute kidney injury.
- Human T-cell lymphotrophic virus infection in organ donors: a need to reassess policy?
- IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia.
- Superior long-term results of simultaneous pancreas-kidney transplantation from pediatric donors.
- Donation after cardiac death: the University of Wisconsin experience.
- Influence of kidney function to the impact of acute rejection on long-term kidney transplant survival.
- Favorable balance of anti-oxidant/pro-oxidant systems and ablated oxidative stress in Brown Norway rats in renal ischemia-reperfusion injury.
Schools
Univ Of Ct Sch Of Med
University Co
University Wi
Procedures Preformed
- Anoscopy With Removal of Anal Tumor
- Appendectomy, Laparoscopic
- Appendectomy, Open
- Arteriovenous Shunt Creation
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Conditions Treated
- Abdominal Pain
- Anorectal Abscess
- Appendicitis
- Atelectasis
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Doctors Specialties
- General Surgery
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Fellow
Education
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University of Colorado -
University of Connecticut School of Medicine
Drug Facts
| NPI NUMBER | 1306898259 | |
| NPPES Provider LastName | SHAMES | |
| NPPES Provider FirstName | BRIAN | |
| NPPES Provider ZIPCode | 060306227 | |
| NPPES Provider State | CT | |
| Specialty Description | General Surgery | |
| Total Claim Count | 40.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1306898259 |
| Last Name Of The Provider | SHAMES |
| First Name Of The Provider | BRIAN |
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