Professor, Surgery, Perelman School of Medicine
General Surgery
Dr. Brian J. Czerniecki, MD
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Brian Czerniecki practices General Surgery. He studied medicine at Rutgers Robert Wood Johnson Medical School. Rutgers Robert Wood Johnson Medical School has a rank of 74 in research and a 67 in primary care He received awards:"America's Top Doctors", "Philadelphia Magazine", "America's Top Doctors for Cancer", "CMS Meaningful Use Stage 1 Certification", "Fellow (FACS)" and "Super Doctor". Brian Czerniecki is also a published doctor. He has 100 paper published. The most recent paper is: Calcium ionophore-treated peripheral blood monocytes and dendritic cells rapidly display characteristics of activated dendritic cells. Doctor Brian J. Czerniecki, MD accepts Medicare payments and is listed with Medicare.gov.
Publications
- Type I-polarized BRAF-pulsed dendritic cells induce antigen-specific CD8+ T cells that impact BRAF-mutant murine melanoma.
- Association of Depressed Anti-HER2 T-Helper Type 1 Response With Recurrence in Patients With Completely Treated HER2-Positive Breast Cancer: Role for Immune Monitoring.
- Resident and Fellow Participation in Breast Surgery: An American College of Surgeons NSQIP Clinical Outcomes Analysis.
- CD4+ T-helper Type 1 Cytokines and Trastuzumab Facilitate CD8+ T-cell Targeting of HER-2/neu-expressing Cancers.
- Optimizing Dendritic Cell-Based Approaches for Cancer Immunotherapy.
- Interference-Free HER2 ECD as a Serum Biomarker in Breast Cancer.
- Radiation as Immunomodulator: Implications for Dendritic Cell-Based Immunotherapy.
- A human ErbB2-specific TCR confers potent anti-tumor effector functions in genetically engineered primary cytotoxic lymphocytes.
- Prognosis of Patients with Melanoma and Microsatellitosis Undergoing Sentinel Lymph Node Biopsy.
- Clark Level Risk Stratifies Patients with Mitogenic Thin Melanomas for Sentinel Lymph Node Biopsy.
- Racial disparities in the use of outpatient mastectomy.
- A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside.
- Local Immune Response Predicts Survival in Patients with Thick (T4) Melanomas.
- Response to HER-2 Pulsed DC1 Vaccines is Predicted by Both HER-2 and Estrogen Receptor Expression in DCIS.
- Immediate reconstruction following nipple-sparing mastectomy: one option for young Breast cancer patients with early stage disease.
- Sartorius transposition during inguinal lymphadenectomy for melanoma.
- Trends in immediate Breast reconstruction across insurance groups after enactment of Breast cancer legislation.
- Factors Influencing Surgical and Adjuvant Therapy in Stage I Breast Cancer: A SEER 18 Database Analysis.
- Extracellular ATP and toll-like receptor 2 agonists trigger in human monocytes an activation program that favors T helper 17.
- Racial disparities in immediate Breast reconstruction after mastectomy: impact of state and federal health policy changes.
- Optical malignancy parameters for monitoring progression of Breast cancer neoadjuvant chemotherapy.
- DCIS in BRCA1 and BRCA2 mutation carriers: prevalence, phenotype, and expression of oncodrivers C-MET and HER3.
- Sentinel lymph node biopsy in Breast cancer: a work in progress.
- Optically measured microvascular blood flow contrast of malignant Breast tumors.
- Inhibition of CD4+CD25+ Regulatory T Cell Function and Conversion into Th1-Like Effectors by a Toll-Like Receptor-Activated Dendritic Cell Vaccine.
- T-cell adoptive therapy of tumors: mechanisms of improved therapeutic performance.
- Diverse functional activity of CD83+ monocyte-derived dendritic cells and the implications for Cancer vaccines.
- Calcium signaling inhibits interleukin-12 production and activates CD83(+) dendritic cells that induce Th2 cell development.
- Cyclosporin A-induced fibroadenomas of the Breast: report of five cases.
- Locally recurrent malignant melanoma characteristics and outcomes: a single-institution study.
- Revolutionary impact of lymphoscintigraphy and intraoperative sentinel node mapping in the clinical practice of oncology.
- The impact of a multidisciplinary Breast cancer center on recommendations for patient management: the University of Pennsylvania experience.
- MR imaging of the Breast in patients with invasive lobular carcinoma.
- Calcium ionophore activation of chronic myelogenous leukemia progenitor cells into dendritic cells is mediated by calcineurin phosphatase.
- MR imaging in patients with nipple discharge: initial experience.
- Accuracy of sentinel lymph node biopsy in patients with large primary Breast tumors.
- Granulocyte-macrophage colony-stimulating factor, interleukin-2, and interleukin-12 synergize with calcium ionophore to enhance dendritic cell function.
- Incidence of sentinel node metastasis in patients with thin primary melanoma (< or = 1 mm) with vertical growth phase.
- Active macromolecule uptake by lymph node antigen-presenting cells: a novel mechanism in determining sentinel lymph node status.
- Sentinel lymph node biopsy with metastasis: can axillary dissection be avoided in some patients with Breast cancer?
- Calcium signaling induces acquisition of dendritic cell characteristics in chronic myelogenous leukemia myeloid progenitor cells.
- Calcium ionophore-treated myeloid cells acquire many dendritic cell characteristics independent of prior differentiation state, transformation status, or sensitivity t...
- 99mTc-human serum albumin: an effective radiotracer for identifying sentinel lymph nodes in melanoma.
- Calcium mobilization in human myeloid cells results in acquisition of individual dendritic cell-like characteristics through discrete signaling pathways.
- Immunohistochemistry with pancytokeratins improves the sensitivity of sentinel lymph node biopsy in patients with Breast carcinoma.
- Calcium ionophore-treated Peripheral blood monocytes and dendritic cells rapidly display characteristics of activated dendritic cells.
- Propagation of mouse and human T cells with defined antigen specificity and function.
- Radiation therapy and Toll-like receptor signaling: implications for the treatment of Cancer.
- Phorbol diacetate inhibits superoxide anion radical production and tumor promotion by mezerein.
- Inhalation of ozone produces a decrease in superoxide anion radical production in mouse alveolar macrophages.
- The role of free radicals in tumor promotion.
- Identification of high-risk patients among those diagnosed with thin cutaneous melanomas.
- Targeting HER-2/neu in early Breast cancer development using dendritic cells with staged interleukin-12 burst secretion.
- Regional nodal metastatic Disease is the strongest predictor of survival in patients with thin vertical growth phase melanomas: a case for SLN Staging biopsy in these ...
- Predicting sentinel node status in AJCC stage I/II primary cutaneous melanoma.
- Biopsy findings after Breast conservation therapy for early-stage invasive Breast cancer.
- Development of vaccines for high-risk ductal carcinoma in situ of the Breast.
- Day-4 myeloid dendritic cells pulsed with whole tumor lysate are highly immunogenic and elicit potent anti-tumor responses.
- A novel dendritic cell-based immunization approach for the induction of durable Th1-polarized anti-HER-2/neu responses in women with early Breast cancer.
- Developing dendritic cell-based therapies to condition immune responses to novel oncogenic proteins and stem cells.
- Optimizing parameters for clinical-scale production of high IL-12 secreting dendritic cells pulsed with oxidized whole tumor cell lysate.
- The significance of HER-2/neu receptor positivity and immunophenotype in ductal Carcinoma in situ with early invasive disease.
- Circulating tumor cells in Breast cancer patients: an evolving role in patient prognosis and disease progression.
- Effect of multiple activation stimuli on the generation of Th1-polarizing dendritic cells.
- Computer aided automatic detection of malignant lesions in diffuse optical mammography.
- It''s all in for the HER family in tumorigenesis.
- Asymptomatic changes in cardiac function can occur in ductal Carcinoma-in-situ patients following treatment with HER-2/neu-pulsed dendritic cell vaccines.
- Differentiation of benign and malignant Breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography.
- HER-2/neu overexpression as a predictor for the transition from in situ to invasive Breast cancer.
- Ductal Carcinoma in situ: state of the science and roadmap to advance the field.
- Differential production of IL-23 and IL-12 by myeloid-derived dendritic cells in response to TLR agonists.
- Method of primary tumor detection as a risk factor for local and distant recurrence after Breast-conservation treatment for early-stage Breast cancer.
- STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells.
- Reengineering dendritic cell-based anti-Cancer vaccines.
- Outcome after treatment of patients with mammographically occult, magnetic resonance imaging-detected Breast cancer presenting with axillary lymphadenopathy.
- Cutting edge: innate immune system discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high-level IL-12 secretion by de...
- MRI before reexcision surgery in patients with Breast cancer.
- Intranodal administration of peptide-pulsed mature dendritic cell vaccines results in superior CD8+ T-cell function in melanoma patients.
- Rapid high efficiency sensitization of CD8+ T cells to tumor antigens by dendritic cells leads to enhanced functional avidity and direct tumor recognition through an I...
- Changes in the surgical management of patients with Breast carcinoma based on preoperative magnetic resonance imaging.
- MR imaging screening of the contralateral Breast in patients with newly diagnosed Breast cancer: preliminary results.
- Magnetic resonance imaging-guided biopsy of mammographically and clinically occult Breast lesions.
- Mature CD83(+) dendritic cells infected with recombinant gp100 vaccinia virus stimulate potent antimelanoma T cells.
- Subareolar and peritumoral injection identify similar sentinel nodes for Breast cancer.
- Use of radiotracer for sentinel lymph node mapping in Breast cancer optimizes staging independent of site of administration.
- High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid- derived dendritic cells is mediated by IL-12 production.
- Repeat operative sentinel lymph node biopsy.
- Human leukocyte antigen-A2-restricted CTL responses to mutated BRAF peptides in melanoma patients.
- Predictors of regional nodal Disease in patients with thin melanomas.
- Diffuse optical measurement of blood flow in Breast tumors.
- Breast cancer detection based on incremental biochemical and physiological properties of Breast cancers: a six-year, two-site study.
- Diffuse optical tomography of Breast cancer during neoadjuvant chemotherapy: a case study with comparison to MRI.
- Dendritic cells in melanoma immunotherapy.
- Mitotic rate as a predictor of sentinel lymph node positivity in patients with thin melanomas.
- Combining innate immunity with radiation therapy for Cancer treatment.
- Skin-sparing mastectomy and immediate reconstruction is an acceptable treatment option for patients with high-risk Breast carcinoma.
- Thin primary cutaneous malignant melanoma: a prognostic tree for 10-year metastasis is more accurate than American Joint Committee on Cancer staging.
- Mammographic appearance of recurrent Breast cancer after Breast conservation therapy.
- Comparison of triple-negative and estrogen receptor-positive/progesterone receptor-positive/HER2-negative Breast carcinoma using quantitative fluorine-18 fluorodeoxygl...
Schools
UmdnjRobert Wood Johnson Medical School
Ohio State University Hospital
National Institute Of Health
Procedures Preformed
- Biopsy of Breast
- Breast Reconstruction
- Excision of Breast Tumor
- Excision, Shaving, or Destruction of Skin and Subcutaneous Tissue (incl. Mohs Micrographic Surgery), Tissue Transfer
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Conditions Treated
- Atelectasis
- Biliary Atresia
- Breast Cancer
- Breast Lump
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Doctors Specialties
- General Surgery
Accepted Insurances
Awards
- America's Top Doctors
- Philadelphia Magazine
- America's Top Doctors for Cancer
- CMS Meaningful Use Stage 1 Certification
- Fellow (FACS)
- Super Doctor
Education
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Ohio State University Hospital -
Rutgers Robert Wood Johnson Medical School
Hospital
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Hospital of the University of Pennsylvania
Drug Facts
| NPI NUMBER | 1881620938 | |
| NPPES Provider LastName | CZERNIECKI | |
| NPPES Provider FirstName | BRIAN | |
| NPPES Provider ZIPCode | 19104 | |
| NPPES Provider State | PA | |
| Specialty Description | Surgical Oncology | |
| Total Claim Count | 62.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1881620938 |
| Last Name Of The Provider | CZERNIECKI |
| First Name Of The Provider | BRIAN |
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