Dean, Morsani College of Medicine, Senior Vice President USF Health, Professor of Obstetrics and Gynecology, Morsani College of Medicine, Professor of Health Policy and Management, College of Public Health, The University of South Florida
Obstetrics & Gynecology
Dr. Charles J. Lockwood, MD
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Charles Lockwood works in the field of Obstetrics & Gynecology. He went to Perelman School of Medicine at the University of Pennsylvania. He has 16 awards "Jesse H. Neal Award for Editorials (2005, 2007, and 2014)", "Pardi Presidents Distinguished Scientist Award", "Faculty award, OSU College of Medicine Gold Humanism Honor Society", "Award for Editorial/Editors Letter category (First Place) (2009, 2011)", "Elected Member, Institute of Medicine", "March of Dimes Awardee", "Gold Prize for Best Poster Presentation", "Second Prize Award for Best Paper in Perinatal Medicine", "Award Paper", "Best Genetic Research in Perinatal Medicine", "Member", "Secretary", "Former Secretary/Treasurer and Presdient", "Advisory Committee for Reproductive Drugs", "Chair of the Committee on Obstetric Practice" and "Human Embryology & Development-1 Study Section (Regular member)". Charles Lockwood is a published doctor and has 101 publications published. The lastest was: 'The role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding.'
Publications
- The role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse Pregnancy outcomes and abnormal uterine bleeding.
- Inflammatory gene networks in term human decidual cells define a potential signature for cytokine-mediated parturition.
- Expression of Interferon γ by Decidual Cells and Natural Killer Cells at the Human Implantation Site: Implications for Preeclampsia, Spontaneous Abortion, and Intraute...
- Chinese herbal medicine for miscarriage affects decidual micro-environment and fetal Growth.
- Mass spectrometry identification of potential mediators of progestin-only contraceptive-induced abnormal Uterine bleeding in human endometrial stromal cells.
- Genetic screening and testing in an episode-based payment model: preserving patient autonomy.
- Unfolded protein response prevents blastocyst formation during preimplantation embryo development in vitro.
- Interferon-γ Protects First-Trimester Decidual Cells against Aberrant Matrix Metalloproteinases 1, 3, and 9 Expression in Preeclampsia.
- Long-Acting Progestin-only Contraceptives Enhance Human Endometrial Stromal Cell Expressed Neuronal Pentraxin-1 and Reactive Oxygen Species to Promote Endothelial Cell...
- A comprehensive obstetric patient safety program reduces liability claims and payments.
- Decidual cell regulation of natural killer cell-recruiting chemokines: implications for the pathogenesis and prediction of preeclampsia.
- System needs to include incentives to improve outcomes, lower costs. Interview by Lois A Bowers.
- Global fees, tiered delivery system could improve primary care. Interview by Lois A Bowers.
- Challenges of healthcare reform, delivery 'exciting' for future doctors. Interview by Lois A Bowers.
- Tort reform, improved technology keys to reducing healthcare system costs. Interview by Lois A Bowers.
- Investigation of genetic risk factors for chronic adult diseases for association with preterm birth.
- Medical education and health policy: what is important for me to know, how do I learn it, and what are the gaps?
- Commentary: a ray of hope for medical school research funding.
- Abruption-Induced Preterm Delivery is Associated with Thrombin-Mediated Functional Progesterone Withdrawal in Decidual Cells.
- Lipopolysaccharide appears to activate human endometrial endothelial cells through TLR-4-dependent and TLR-4-independent mechanisms.
- Depression and serotonin reuptake inhibitor treatment as risk factors for preterm birth.
- Toll-like receptor 4 expression in decidual cells and interstitial trophoblasts across human Pregnancy.
- Effects of etonogestrel treatment in the reproductive organs and Uterine arteries of nonoophorectomized guinea pigs.
- Pro-inflammatory cytokine-stimulated first trimester decidual cells enhance macrophage-induced apoptosis of extravillous trophoblasts.
- American Thoracic Society documents: an official American Thoracic Society/Society of Thoracic Radiology Clinical Practice Guideline--Evaluation of Suspected Pulmonar...
- An official American Thoracic Society/Society of Thoracic Radiology clinical practice guideline: evaluation of suspected pulmonary embolism in Pregnancy.
- Heparin Elevates Circulating Soluble fms-Like Tyrosine Kinase-1 Immunoreactivity in Pregnant Women Receiving Anticoagulation Therapy.
- Aspirin and heparin effect on Basal and antiphospholipid antibody modulation of trophoblast function.
- Does Antidepressant Use Attenuate the Risk of a Major Depressive Episode in Pregnancy?
- Novel therapies targeting endometriosis.
- Abruption-associated prematurity.
- Tissue factor expression in Ovarian cancer: implications for immunotherapy with hI-con1, a factor VII-IgGF(c) chimeric protein targeting tissue factor.
- Expression of tissue factor in adenocarcinoma and squamous cell carcinoma of the Uterine cervix: implications for immunotherapy with hI-con1, a factor VII-IgGFc chimer...
- Preterm deliveries that result from multiple Pregnancies associated with assisted reproductive technologies in the USA: a cost analysis.
- Focal increases of fetal macrophages in placentas from Pregnancies with histological chorioamnionitis: potential role of fibroblast monocyte chemotactic protein-1.
- Mechanisms of Normal and Abnormal Endometrial Bleeding.
- A comprehensive obstetrics patient safety program improves safety climate and culture.
- Decidual hemostasis, inflammation, and angiogenesis in pre-eclampsia.
- The effects of thrombin and cytokines upon the biomechanics and remodeling of isolated amnion membrane, in vitro.
- Novel insights into molecular mechanisms of abruption-induced preterm birth.
- The implication of aberrant GM-CSF expression in decidual cells in the pathogenesis of preeclampsia.
- Regulation of interleukin-6 expression in human decidual cells and its potential role in chorioamnionitis.
- Preeclampsia-related increase of interleukin-11 expression in human decidual cells.
- Alpha-lipoic acid inhibits thrombin-induced fetal membrane weakening in vitro.
- hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor for immunotherapy of Uterine serous papillary carcinoma.
- Thrombophilias and stillbirth.
- Mortality of mothers from cardiovascular and non-cardiovascular causes following Pregnancy complications in first delivery.
- Long-term progestin contraceptives (LTPOC) induce aberrant angiogenesis, oxidative stress and apoptosis in the guinea pig uterus: A model for abnormal Uterine bleeding...
- Human labor is associated with reduced decidual cell expression of progesterone, but not glucocorticoid, receptors.
- The immunoconjugate "icon" targets aberrantly expressed endothelial tissue factor causing regression of endometriosis.
- Weight gain recommendations in Pregnancy and the obesity epidemic.
- Involvement of human decidual cell-expressed tissue factor in Uterine hemostasis and abruption.
- Increased plasma soluble fms-like tyrosine kinase 1 and endoglin levels in Pregnancies complicated with preeclampsia.
- Tissue factor and the endometrium: from physiology to pathology.
- Intra-amniotic infection upregulates decidual cell vascular endothelial Growth factor (VEGF) and neuropilin-1 and -2 expression: implications for infection-related pre...
- Progestin and thrombin regulate tissue factor expression in human term decidual cells.
- Case records of the Massachusetts General Hospital. Case 16-2009. A 32-year-old pregnant woman with an abnormal fetal ultrasound study.
- Mechanisms of leukocyte accumulation and activation in chorioamnionitis: interleukin 1 beta and tumor necrosis factor alpha enhance colony stimulating factor 2 express...
- Impact of a comprehensive patient safety strategy on obstetric adverse events.
- Inflammation and Pregnancy.
- Decidualized human endometrial stromal cells mediate hemostasis, angiogenesis, and abnormal Uterine bleeding.
- Elevated first trimester soluble fibrin polymer is associated with adverse Pregnancy outcome in thrombophilic patients.
- Placental expression of ceruloplasmin in Pregnancies complicated by severe preeclampsia.
- Fractional excretion of tumor necrosis factor-alpha in women with severe preeclampsia.
- Preeclampsia-related inflammatory cytokines regulate interleukin-6 expression in human decidual cells.
- Matrix metalloproteinase 9 (MMP9) expression in preeclamptic decidua and MMP9 induction by tumor necrosis factor alpha and interleukin 1 beta in human first trimester ...
- Preface: novel features of the physiology and pathology of human reproduction.
- Endometriosis and tissue factor.
- Decidual cell-expressed tissue factor in human Pregnancy and its involvement in hemostasis and preeclampsia-related angiogenesis.
- Single nucleotide polymorphisms in the human progesterone receptor gene and spontaneous preterm birth.
- Pre-eclampsia is associated with dendritic cell recruitment into the Uterine decidua.
- Progestin-inflammatory cytokine interactions affect matrix metalloproteinase-1 and -3 expression in term decidual cells: implications for treatment of chorioamnionitis...
- Thromboembolism in Pregnancy.
- Use of recombinant activated factor VII for massive Postpartum hemorrhage.
- The role of macrophage migration inhibitory factor in maintaining the immune privilege at the fetal-maternal interface.
- Expression of Toll-like receptors in the human decidua.
- Progestin inhibits and thrombin stimulates the plasminogen activator/inhibitor system in term decidual stromal cells: implications for parturition.
- Thrombin regulates soluble fms-like tyrosine kinase-1 (sFlt-1) expression in first trimester decidua: implications for preeclampsia.
- Chorionic villus sampling significantly affects fetal cardiovascular function.
- Thrombin regulates monocyte chemoattractant protein-1 expression in human first trimester and term decidual cells.
- Antithrombotic prophylaxis in multiparous women with preeclampsia or intrauterine growth retardation in an antecedent Pregnancy.
- Differential regulation of colony stimulating factor 1 and macrophage migration inhibitory factor expression by inflammatory cytokines in term human decidua: implicati...
- The role of decidualization in regulating endometrial hemostasis during the Menstrual cycle, gestation, and in pathological states.
- Magnesium sulfate tocolysis: time to quit.
- Thrombin activation of endometrial endothelial cells: a possible role in Intrauterine growth restriction.
- Proteomic profiling of the amniotic fluid to detect inflammation, infection, and neonatal sepsis.
- Pregnancy-associated changes in the hemostatic system.
- Regulation of chemokine production in response to pro-inflammatory cytokines in first trimester decidual cells.
- Prior cesarean delivery is not associated with an increased risk of stillbirth in a subsequent Pregnancy: analysis of U.S. perinatal mortality data, 1995-1997.
- Tumor necrosis factor-alpha and interleukin-1beta regulate interleukin-8 expression in third trimester decidual cells: implications for the genesis of chorioamnionitis.
- Analysis of circulating annexin A5 parameters during Pregnancy: absence of differences between women with recurrent spontaneous Pregnancy losses and controls.
- Long-term progestin-only contraceptives result in reduced endometrial blood flow and oxidative stress.
- Tibolone exerts proGestational inhibition of matrix metalloproteinase expression in human endometrial stromal cells.
- Elevated first trimester maternal levels of soluble fibrin polymer are associated with lower birthweight in twin gestation.
- Thrombin and interleukin-1beta regulate HOXA10 expression in human term decidual cells: implications for preterm labor.
- Fractional excretion of angiogenic factors in women with severe preeclampsia.
- Intercellular adhesion molecule-1 expression in human endometrium: implications for long term progestin only contraception.
- Regulation of monocyte chemoattractant protein-1 expression by tumor necrosis factor-alpha and interleukin-1beta in first trimester human decidual cells: implications ...
- A low vaginal "pool" amniotic fluid glucose measurement is a predictive but not a sensitive marker for infection in women with preterm premature rupture of m...
- Reduction of circulating annexin A5 levels and resistance to annexin A5 anticoagulant activity in women with recurrent spontaneous Pregnancy losses.
Schools
University Of Pennsylvania School Of Medicine
Pennsylvania Hospital
The Ohio State University College of Medicine Vice President for Health Sciences
The Ohio State University College of Medicine Dean
Procedures Preformed
- Vaginal Birth After Cesarean (VBAC)
Conditions Treated
- Encounters for High-Risk Pregnancies
- Gestational Diabetes
- Hypertension Complicating Pregnancy, Childbirth and Postpartum
- IntraUterine Growth Restriction
- View All
Doctors Specialties
- Maternal-Fetal Medicine
- Obstetrics
- Gynecology
Accepted Insurances
Awards
- Jesse H. Neal Award for Editorials (2005, 2007, and 2014)
- Pardi President’s Distinguished Scientist Award
- Faculty award, OSU College of Medicine Gold Humanism Honor Society
- Award for Editorial/Editor’s Letter category (First Place) (2009, 2011)
- Elected Member, Institute of Medicine
- March of Dimes Awardee
- Gold Prize for Best Poster Presentation
- Second Prize Award for Best Paper in Perinatal Medicine
- Award Paper
- Best Genetic Research in Perinatal Medicine
- Member
- Secretary
- Former Secretary/Treasurer and Presdient
- Advisory Committee for Reproductive Drugs
- Chair of the Committee on Obstetric Practice
- Human Embryology & Development-1 Study Section (Regular member)
Education
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Harvard University, School of Public Health -
Yale University -
Yale New Haven Children's Center -
Pennsylvania Hospital - University of Pennsylvania Health System -
Perelman School of Medicine at the University of Pennsylvania -
Brown University
Hospital
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Tampa General Hospital
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