Assistant Professor of Medicine and Cancer Biology
Oncology
Dr. Christine M. Lovly, MD
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Christine Lovly works in the field of Oncology. She went to Washington University School of Medicine in St. Louis. She received 1 awards: "Damon Runyon Clinical Investigator Award". Christine Lovly is a published doctor as well. She has 24 publications published. The latest was: Fragments of ATM which have dominant-negative or complementing activity.
Publications
- Correlation between KRAS mutation status and response to chemotherapy in patients with advanced non-small cell lung cancer☆.
- EGFR Kinase Domain Duplication (EGFR-KDD) Is a Novel Oncogenic Driver in Lung Cancer That Is Clinically Responsive to Afatinib.
- Impact of NRAS Mutations for Patients with Advanced Melanoma Treated with Immune Therapies.
- Optimizing the sequence of anti-EGFR-targeted therapy in EGFR-mutant lung cancer.
- Expression of ROS1 predicts ROS1 gene rearrangement in inflammatory myofibroblastic tumors.
- Therapeutic Strategies Utilized in the Setting of Acquired Resistance to EGFR Tyrosine Kinase Inhibitors.
- Prognostic impact of KRAS mutation subtypes in 677 patients with metastatic lung adenocarcinomas.
- Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer.
- Molecular pathways: resistance to kinase inhibitors and implications for therapeutic strategies.
- Enabling a Genetically Informed Approach to Cancer Medicine: A Retrospective Evaluation of the Impact of Comprehensive Tumor Profiling Using a Targeted Next-Generation...
- Beyond Histology: Translating Tumor Genotypes into Clinically Effective Targeted Therapies.
- A Patient With Metastatic Lung Adenocarcinoma Harboring Concurrent EGFR L858R, EGFR Germline T790M, and PIK3CA Mutations: The Challenge of Interpreting Results of Comp...
- Fragments of ATM which have dominant-negative or complementing activity.
- Escaping ALK Inhibition: Mechanisms of and Strategies to Overcome Resistance.
- ALK mutations conferring differential resistance to structurally diverse ALK inhibitors.
- Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinase inhibitors.
- Lung cancer in 2010: One size does not fit all.
- Regulation of Chk2 ubiquitination and signaling through autophosphorylation of serine 379.
- Identification of protein phosphorylation sites within Ser/Thr-rich cluster domains using site-directed mutagenesis and hybrid linear quadrupole ion trap Fourier trans...
- The role of NF-{kappa}B-1 and NF-{kappa}B-2-mediated resistance to apoptosis in lymphomas.
- Accurate mass-driven analysis for the characterization of protein phosphorylation. Study of the human Chk2 protein kinase.
- Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation.
- Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding.
Schools
Washington Univ Sch Of Med
Doctors Specialties
- Hematology
- Oncology
Accepted Insurances
Awards
- Damon Runyon Clinical Investigator Award
Education
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Vanderbilt University -
Washington University School of Medicine in St. Louis
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