Physician
Internal Medicine
Dr. Darrin Beaupre, MD
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Doctor Darrin Beaupre, MD works in the field of Internal Medicine. He studied medicine at University of Texas Medical School. Darrin Beaupre, MD has written publications. He has 13 publications published with PubMed. The lastest publication is: 'Phase I Study of U3-1287, a Fully Human Anti-HER3 Monoclonal Antibody, in Patients with Advanced Solid Tumors.'
Publications
- Phase I Study of U3-1287, a Fully Human Anti-HER3 Monoclonal Antibody, in Patients with Advanced Solid Tumors.
- Tipifarnib-induced apoptosis in acute myeloid leukemia and multiple myeloma cells depends on Ca2+ influx through plasma membrane Ca2+ channels.
- A phase Ib study of AMG 102 in combination with bevacizumab or motesanib in patients with advanced solid tumors.
- Safety, pharmacokinetics, and pharmacodynamics of AMG 102, a fully human hepatocyte growth factor-neutralizing monoclonal antibody, in a first-in-human study of patien...
- Tipifarnib and bortezomib are synergistic and overcome cell adhesion-mediated drug resistance in multiple myeloma and acute myeloid leukemia.
- Characterization of a R115777-resistant human multiple myeloma cell line with cross-resistance to PS-341.
- Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple...
- R115777 induces Ras-independent apoptosis of myeloma cells via multiple intrinsic pathways.
- Farnesyl transferase inhibitors enhance death receptor signals and induce apoptosis in multiple myeloma cells.
- RAS inhibitors in hematologic cancers: biologic considerations and clinical applications.
- Autocrine interleukin-1beta production in leukemia: evidence for the involvement of mutated RAS.
- RAS and leukemia: from basic mechanisms to gene-directed therapy.
Schools
University of Texas At Houston Medical School At Houston
University MiamiJackson Mem Hospital
University MiamiJackson Meml Hospital
Doctors Specialties
- Hematology
- Medical Oncology
- Oncology
- Internal Medicine
Accepted Insurances
Education
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Jackson Memorial Hospital - Jackson Health System -
University of Texas Medical School
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