Professor, Medicine and Microbial Pathogenesis and Immunology, Texas AandM Health Science Center College of Med; Associate Dean, Houston Campus; Director, Clinical Science and Translational Research Institute
Allergy & Immunology
Dr. David P. Huston, MD
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David P. Huston works in the field of Allergy & Immunology. He went to Baylor College of Medicine. He received 3 awards: "Fellow (FAAAAI)", "Top MD" and "Fellow (FACR)". David Huston is a published physician. He published 62 publications, including: 'GM-CSF, IL-5 and RANTES immunoreactivity and mRNA expression in chronic hyperplastic sinusitis with nasal polyposis (NP).'
Publications
- Emerging role of human basophil biology in health and disease.
- Therapeutic Strategies for Harnessing Human Eosinophils in Allergic Inflammation, Hypereosinophilic Disorders, and Cancer.
- Defects in Interleukin-17 Immunity in the Pathogenesis of Chronic Mucocutaneous Candidiasis.
- A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma.
- Immune dysregulation in the pathogenesis of pulmonary alveolar proteinosis.
- Defective B-cell response to Toll-like receptor-9 ligands in common variable immunodeficiency.
- Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRalpha gene in the X chromosome pseudoautosomal region 1.
- IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells.
- JAK kinases control IL-5 receptor ubiquitination, degradation, and internalization.
- Thymic stromal lymphopoietin:a potential therapeutic target for allergy and asthma.
- CXCL13 neutralization reduces the severity of collagen-induced arthritis.
- Reduction of the incidence and severity of collagen-induced arthritis by constitutive Nur77 expression in the T cell lineage.
- Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes.
- Biology of common beta receptor-signaling cytokines: IL-3, IL-5, and GM-CSF.
- Interleukins-4, -5, and -13: emerging therapeutic targets in allergic disease.
- Therapeutic efficacy of an anti-IL-5 monoclonal antibody delivered into the respiratory tract in a murine model of asthma.
- IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: relationship to expression of allergic disease.
- Proteasomal regulation of betac signaling reveals a novel mechanism for cytokine receptor heterotypic desensitization.
- Interleukin-5, a therapeutic target in allergic inflammation.
- Human B cells express IL-5 receptor messenger ribonucleic acid and respond to IL-5 with enhanced IgM production after mitogenic stimulation with Moraxella catarrhalis.
- IL-13 production by allergen-stimulated T cells is increased in allergic disease and associated with IL-5 but not IFN-gamma expression.
- Production of IL-5 and granulocyte-macrophage colony-stimulating factor by naive human mast cells activated by high-affinity IgE receptor ligation.
- Secretion of the eosinophil-active cytokines interleukin-5, granulocyte/macrophage colony-stimulating factor and interleukin-3 by bronchoalveolar lavage CD4+ and CD8+ ...
- Late response to allergen is associated with increased concentrations of tumor necrosis factor-alpha and IL-5 in induced sputum.
- Proliferation and release of IL-5 and IFN-gamma by peripheral blood mononuclear cells from cat-allergic asthmatics and rhinitics, non-cat-allergic asthmatics, and norm...
- Behçet's-like syndrome associated with idiopathic CD4+ T-lymphocytopenia, opportunistic infections, and a large population of TCR alpha beta+ CD4- CD8- T cells.
- Regulation of primary cytotoxic T lymphocyte responses generated during mixed leukocyte culture with H-2d identical Qa-1-disparate cells.
- IL-5 production by allergen-stimulated T cells following grass pollen immunotherapy for seasonal allergic rhinitis.
- Engineering of a functional interleukin-5 monomer: a paradigm for redesigning helical bundle cytokines with therapeutic potential in allergy and asthma.
- Delineation of IL-5 domains predicted to engage the IL-5 receptor complex.
- Suppression of Ia-unrestricted primary anti-Qa-1 cytotoxic T lymphocyte responses by class II major histocompatibility complex-restricted cellular interactions.
- Creation of a biologically active interleukin-5 monomer.
- Therapy of chronic idiopathic urticaria with nifedipine: demonstration of beneficial effect in a double-blinded, placebo-controlled, crossover trial.
- Previously undiagnosed hyper-IgE syndrome in an adult with multiple systemic fungal infections.
- Immunoglobulin deficiency syndromes and therapy.
- Variable expression of IgG2 deficiency.
- T cell abnormalities in NZB mice occur independently of autoantibody production.
- GM-CSF, IL-5 and RANTES immunoreactivity and mRNA expression in chronic hyperplastic sinusitis with nasal polyposis (NP).
- Enhanced detection of human IL-5 in biological fluids utilizing murine monoclonal antibodies which delineate distinct neutralizing epitopes.
- Primary cell-mediated lympholysis response to a maternally transmitted antigen.
- American Academy of Allergy and Immunology Training Program Directors' Retreat, Jan. 10-12, 1992. Core curriculum outline.
- Abnormal response to IL-5 in B-cell chronic lymphocytic leukemia.
- NZB cytotoxic lymphocyte responses. Kinetic analyses.
- Natural killer cell suppression of IgM production.
- Understanding the pathogenesis of allergic asthma using mouse models.
- Requlation of cytotoxic lymphocyte responses in New Zealand mice by alloantigen-activated spleen cells.
- Subcutaneous nodular amyloidosis: a case report and review of the literature.
- Allergen-induced proliferation and interleukin-5 production by bronchoalveolar lavage and blood T cells after segmental allergen challenge.
- Versatile E. coli thioredoxin specific monoclonal antibodies afford convenient analysis and purification of prokaryote expressed soluble fusion protein.
- Parafalcine and bilateral convexity neurosarcoidosis mimicking meningioma: case report and review of the literature.
- Mechanism of Staphylococcus aureus exotoxin A inhibition of Ig production by human B cells.
- Controlled pilot trial of monthly intravenous cyclophosphamide in multiple sclerosis.
- Differences in maternal lineages of New Zealand Black mice defined by restriction endonuclease analysis of mitochondrial DNA and by expression of maternally transmitte...
- Prevention of mast-cell degranulation by ketotifen in patients with physical urticarias.
- Core content outline for clinical and laboratory immunology. AAAI Training Program Directors' Committee.
- Wegener's granulomatosis presenting with unilateral parotid enlargement.
- Relief of malignant obstructive jaundice by percutaneous insertion of a permanent prosthesis in the biliary tree.
- Preferential lysis of undifferentiated thymocytes by natural thymocytotoxic antibodies from New Zealand black mice.
- Effects of the thymic microenvironment on autoantibody production in (NZB X NZW)F1 mice.
- Cellular requirements for the generation of primary cell-mediated lympholysis responses to Qa-1 antigens.
- The biology of the immune system.
Schools
Wake Forest University
Baylor College Of Med
National Institute Of Health
Doctors Specialties
- Rheumatology
- Allergy
- Immunology
Accepted Insurances
Awards
- Fellow (FAAAAI)
- Top MD
- Fellow (FACR)
Education
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Baylor College of Medicine -
Wake Forest School of Medicine
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