Assistant Professor, Microbiology and Immunology, Harvard Medical School

Infectious Disease

Deborah T. Hung practices Infectious Disease. She studied medicine at Harvard Medical School. Harvard Medical School is a one of the best medicals schools. Harvard Medical School is ranked 1 in research and 12 in primary care medicine Doctor Deborah T. Hung, MD is also published. She has 42 publications published. The lastest publication: "Therapeutic myocardial angiogenesis using percutaneous intrapericardial drug delivery.'

Publications

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• Simultaneous generation of many RNA-seq libraries in a single reaction.
• Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth.
• Bacterial toxins and small molecules elucidate endosomal trafficking.
• Synthesis and structure-activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32.
• Identification of Novel Inhibitors of Nonreplicating Mycobacterium tuberculosis Using a Carbon Starvation Model.
• Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.
• CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells.
• Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response.
• Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.
• Identification of Novel Host-Targeted Compounds That Protect from Anthrax Lethal Toxin-Induced Cell Death.
• Reply to Guy et al.: Support for a bottleneck in the 2011 Escherichia coli O104:H4 outbreak in Germany.
• The Two-Component Sensor KinB Acts as a Phosphatase To Regulate Pseudomonas aeruginosa Virulence.
• Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening.
• Resuscitation-Promoting Factors Are Required for ?-Lactam Tolerance and the Permeability Barrier in Mycobacterium tuberculosis.
• Systematics-guided bioprospecting for bioactive microbial natural products.
• The two-component sensor kinase KinB acts as a non-canonical switch between acute and chronic infection.
• GRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro.
• The sensor kinase KinB regulates virulence in acute Pseudomonas aeruginosa infection.
• The fast track to multidrug resistance.
• Targeting multiple biofilm pathways.
• Toward a systems-level analysis of infection biology: a new method for conducting genetic screens in human cells.
• Chemical tools for dissecting bacterial physiology and virulence.
• Pseudomonas aeruginosa infection of zebrafish involves both host and pathogen determinants.
• Sensitive, specific polymorphism discovery in bacteria using massively parallel sequencing.
• Targeting virulence: a new paradigm for antimicrobial therapy.
• Virstatin inhibits dimerization of the transcriptional activator ToxT.
• Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization.
• Bile acids induce cholera toxin expression in Vibrio cholerae in a ToxT-independent manner.
• Probing bacterial pathogenesis with genetics, genomics, and chemical biology: past, present, and future approaches.
• Productive steps toward an antimicrobial targeting virulence.
• Bile acids stimulate biofilm formation in Vibrio cholerae.
• Chemical biology and bacteria: not simply a matter of life or death.
• Independent Large Scale Duplications in Multiple M. tuberculosis Lineages Overlapping the Same Genomic Region.
• (+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest.
• Understanding and controlling the cell cycle with natural products.
• Distinct binding and cellular properties of synthetic (+)- and (-)-discodermolides.
• Intracoronary and intravenous administration of basic fibroblast growth factor: myocardial and tissue distribution.
• Subxyphoid access of the normal pericardium: a novel drug delivery technique.
• Intrapericardial delivery of fibroblast growth factor-2 induces neovascularization in a porcine model of chronic myocardial ischemia.
• Modulation of myocardial perfusion and vascular reactivity by pericardial basic fibroblast growth factor: insight into ischemia-induced reduction in endothelium-depend...
• Therapeutic myocardial angiogenesis using percutaneous intrapericardial drug delivery.

Schools

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• Harvard Medical School

• Brigham and Women39s Hospital

• Brigham and Womens Hospital

• Harvard University

Doctors Specialties

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• Critical Care Medicine
• Infectious Disease Medicine
• Infectious Disease

Accepted Insurances

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Education

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• Massachusetts General Hospital
• Harvard Medical School

Hospital

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• Brigham and Women's Hospital

Helpful Reviews

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Medicare Facts

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National Provider Identifier [NPI]	1629068267
Last Name Of The Provider	HUNG
First Name Of The Provider	DEBORAH
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