Associate Professor/Yale University
Pathology
Dr. Demetrios T. Braddock, MD
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Doctor Demetrios T. Braddock, MD is an expert in the field of Pathology. He studied medicine at University of Chicago Pritzker School of Medicine. University of Chicago Pritzker School of Medicine is ranked 10/19 in Research/PrimaryCare. Demetrios Braddock is a published MD. He has 21 papers published. The most current publication "Structure-function relationships in side chain lactam cross-linked peptide models of a conserved N-terminal domain of apolipoprotein E."
Publications
- MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.
- The Molecular Basis of Purinergic Signal Metabolism by Ecto-Nucleotide Pyrophosphatase/Phosphodiesterases 4 and 1 and Implications in Stroke.
- Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase.
- NPP4 is a procoagulant enzyme on the surface of vascular endothelium.
- Kinetic analysis of Autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution.
- Quantitative characterization of the interactions among c-myc transcriptional regulators FUSE, FBP, and FIR.
- Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion.
- Histopathologic and molecular aspects of CD56+ natural killer/ T-cell Lymphoma of the testis.
- NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter.
- Research on physical activity and disability: an emerging national priority.
- Treatment of autoimmune premature ovarian failure.
- Conformationally specific enhancement of receptor-mediated LDL binding and internalization by peptide models of a conserved anionic N-terminal domain of human apolipop...
- Structural and thermodynamic characterization of a bioactive peptide model of apolipoprotein E: side-chain lactam bridges to constrain the conformation.
- Structure-function relationships in side chain lactam cross-linked peptide models of a conserved N-terminal domain of apolipoprotein E.
- Biophysical characterization of gp41 aggregates suggests a model for the molecular mechanism of HIV-associated neurological damage and dementia.
- Rapid identification of medium- to large-scale interdomain motion in modular proteins using dipolar couplings.
- Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition.
- Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA.
- Structure and dynamics of KH domains from FBP bound to single-stranded DNA.
- Autotaxin and lipid signaling pathways as anticancer targets.
Schools
U Of Chgo Div Of Bio Sci Pritzker Sch Of Med
Conditions Treated
- Acute Leukemia
- Anemia
- Leukocytosis
- Lymphoma
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Doctors Specialties
- Hematology
- Hematopathology
- Pathology
Accepted Insurances
Education
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National Institutes of Health Clinical Center -
University of Chicago Pritzker School of Medicine
Hospital
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Yale-New Haven Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1720069024 |
| Last Name Of The Provider | BRADDOCK |
| First Name Of The Provider | DEMETRIOS |
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