Professor, Internal Medicine, University of Iowa Roy J. and Lucille A. Carver COM
Cardiology
Dr. Donald D. Heistad, MD
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Doctor Donald D. Heistad, MD practices Cardiology. He went to University of Chicago Pritzker School of Medicine. University of Chicago Pritzker School of Medicine has a rank of 10 in research and a 19 in primary care He received 1 awards: "Elected Member". Dr. Donald D. Heistad is also a published MD. He has 100 paper published. The most recent paper is: Atherosclerosis stabilization with PCSK-9 inhibition: An evolving concept for cardiovascular prevention. He accepts Medicare payments and is registered with Medicare.gov.
Publications
- Atherosclerosis stabilization with PCSK-9 inhibition: An evolving concept for cardiovascular prevention.
- Lipoprotein-associated phospholipase A2 and Aortic stenosis: biomarker or new target for an old foe?
- Novel Role for Endogenous Hepatocyte Growth Factor in the Pathogenesis of Intracranial Aneurysms.
- The role of valvular endothelial cell paracrine signaling and matrix elasticity on valvular interstitial cell activation.
- Aortic Valve Sclerosis in Mice Deficient in Endothelial Nitric Oxide Synthase.
- Promising neuroprotective effects of the angiotensin-(1-7)-angiotensin-converting enzyme 2-Mas axis in stroke.
- Fibrocalcific Aortic valve disease: opportunity to understand disease mechanisms using mouse models.
- Introduction to the compendium on calcific Aortic valve disease.
- Two ways to make great contributions.
- Evidence that acetylsalicylic Acid attenuates inflammation in the walls of human cerebral Aneurysms: preliminary results.
- Vascular function during prolonged progression and regression of atherosclerosis in mice.
- Pioglitazone attenuates valvular calcification induced by hypercholesterolemia.
- Early change in ferumoxytol-enhanced magnetic resonance imaging signal suggests unstable human cerebral Aneurysm: a pilot study.
- Impact of ACE2 Deficiency and Oxidative Stress on Cerebrovascular Function With Aging.
- Calcific Aortic valve disease: not simply a degenerative process: a review and agenda for research from the national heart and lung and blood institute Aortic stenosis...
- Calcific Aortic valve stenosis: methods, models, and mechanisms.
- No answer to Alzheimer's Disease?
- Evidence for active regulation of pro-osteogenic signaling in advanced Aortic valve disease.
- MnSOD protects against COX1-mediated endothelial dysfunction in chronic Heart failure.
- Critical role for copper/zinc-superoxide dismutase in preventing spontaneous intracerebral hemorrhage during Acute and chronic hypertension in mice.
- EP1c times for angiotensin: EP1 receptors facilitate angiotensin II-induced vascular dysfunction.
- Spontaneous intracerebral hemorrhage during Acute and chronic hypertension in mice.
- Serotonin produces monoamine oxidase-dependent oxidative stress in human heart Valves.
- Biventricular adaptation to volume overload in mice with Aortic regurgitation.
- Protective effect of extracellular superoxide dismutase on endothelial function during aging.
- Lowering plasma cholesterol levels halts progression of Aortic valve disease in mice.
- Remodelling of small cerebral arteries in human Hypertension: structural and functional alterations.
- Novel aspects of oxidative stress in cardiovascular Diseases.
- Superoxide dismutase gene transfer reduces portal pressure in CCl4 cirrhotic rats with portal Hypertension.
- Endothelial function in the time of the giants.
- Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific Aortic valvular stenosis in humans.
- Oxidative stress through activation of NAD(P)H oxidase in hypertensive mice with spontaneous intracranial hemorrhage.
- Shear stress influences spatial variations in vascular Mn-SOD expression: implication for LDL nitration.
- Gene transfer after subarachnoid hemorrhage: a tool and potential therapy.
- Role of angiotensin II in endothelial dysfunction induced by lipopolysaccharide in mice.
- Effects of a common human gene variant of extracellular superoxide dismutase on endothelial function after endotoxin in mice.
- Central gene transfer of interleukin-10 reduces hypothalamic inflammation and evidence of Heart failure in rats after myocardial infarction.
- Cerebral vascular dysfunction during hypercholesterolemia.
- Vascular endothelium summary statement I: Health promotion and chronic Disease prevention.
- Two views on plaque rupture.
- Gene therapy for stroke: 2006 overview.
- Increased plasma oxidized phospholipid:apolipoprotein B-100 ratio with concomitant depletion of oxidized phospholipids from atherosclerotic lesions after dietary lipid...
- Calcific Aortic valve stenosis in old hypercholesterolemic mice.
- Modulation of dilator responses of cerebral arterioles by extracellular superoxide dismutase.
- MnSOD deficiency increases endothelial dysfunction in ApoE-deficient mice.
- Endocytosis of extracellular superoxide dismutase into endothelial cells: role of the heparin-binding domain.
- Impairment of dilator responses of cerebral arterioles during diabetes mellitus: role of inducible NO synthase.
- Vascular effects of a common gene variant of extracellular superoxide dismutase in Heart failure.
- Gene transfer of extracellular superoxide dismutase protects against vascular dysfunction with aging.
- Recommendations of the National Heart, Lung, and Blood Institute working group on cerebrovascular biology and Disease.
- Oxidative stress and vascular Disease: 2005 Duff lecture.
- Renal thrombotic microangiopathy in a genetic model of Hypertension in mice.
- Peroxynitrite hyperpolarizes smooth muscle and relaxes internal carotid Artery in rabbit via ATP-sensitive K+ channels.
- Vascular effects of the human extracellular superoxide dismutase R213G variant.
- Mechanisms of inducible nitric oxide synthase-mediated vascular dysfunction.
- Gene transfer of extracellular superoxide dismutase improves endothelial function in rats with Heart failure.
- Vascular interleukin-10 protects against LPS-induced vasomotor dysfunction.
- Activation of Rho-associated kinase during augmented contraction of the basilar Artery to serotonin after subarachnoid hemorrhage.
- Spontaneous stroke in a genetic model of Hypertension in mice.
- Targeting cerebral arteries for gene therapy.
- Gene transfer of extracellular superoxide dismutase failed to prevent cerebral vasospasm after experimental subarachnoid hemorrhage.
- Vasomotor responses in MnSOD-deficient mice.
- Gene transfer of extracellular superoxide dismutase improves relaxation of aorta after treatment with endotoxin.
- Neuronal expression and regulation of CGRP promoter activity following viral gene transfer into cultured trigeminal ganglia neurons.
- Unstable Coronary-artery plaques.
- Gene-targeted mice reveal a critical role for inducible nitric oxide synthase in vascular dysfunction during diabetes.
- Endothelin-1 stimulates arterial VCAM-1 expression via NADPH oxidase-derived superoxide in mineralocorticoid Hypertension.
- Mikamo Lecture: a radical view on the ''superfamily'' of cardiovascular risk factors.
- Gene therapy for cerebral vascular Disease: update 2003.
- Gene transfer of extracellular superoxide dismutase reduces arterial pressure in spontaneously hypertensive rats: role of heparin-binding domain.
- Gene transfer of extracellular superoxide dismutase reduces cerebral vasospasm after subarachnoid hemorrhage.
- Task Force on Strategic Research Direction: Basic Science Subgroup key science topics report.
- Effect of hyperhomocysteinemia on protein C activation and activity.
- Gene transfer of inducible nitric oxide synthase impairs relaxation in human and rabbit cerebral arteries.
- Anticoagulant responses to thrombin are enhanced during regression of atherosclerosis in monkeys.
- Genetic association studies.
- Posttreatment with adenovirus-mediated gene transfer of calcitonin gene-related peptide to reverse cerebral vasospasm in dogs.
- Interleukin-10 protects nitric oxide-dependent relaxation during diabetes: role of superoxide.
- Quantification of mRNA for endothelial NO synthase in mouse blood vessels by real-time polymerase chain reaction.
- Regression of atherosclerosis in monkeys reduces vascular superoxide levels.
- Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of Hypertension.
- Gene transfer to blood vessels using adenoviral vectors.
- Virally mediated gene transfer to the vasculature.
- What's new in the cerebral microcirculation? Landis Award lecture.
- Cationic polymer and lipids augment adenovirus-mediated gene transfer to cerebral arteries in vivo.
- NO-dependent vasorelaxation is impaired after gene transfer of inducible NO-synthase.
- Arachidonate dilates basilar Artery by lipoxygenase-dependent mechanism and activation of K(+) channels.
- Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice.
- Gene transfer to blood vessels: a research tool and potential therapy.
- Mechanisms that produce nitric oxide-mediated relaxation of cerebral arteries during atherosclerosis.
- Supplementation of atherogenic diet with B vitamins does not prevent atherosclerosis or vascular dysfunction in monkeys.
- Vascular cell adhesion molecule-1 augments adenovirus-mediated gene transfer.
- The future of gene therapy for stroke.
- Gene transfer of extracellular superoxide dismutase increases superoxide dismutase activity in cerebrospinal fluid.
- Tumor necrosis factor-alpha impairs contraction but not relaxation in carotid arteries from iNOS-deficient mice.
- Gene transfer of calcitonin gene-related peptide prevents vasoconstriction after subarachnoid hemorrhage.
- IL-10 deficiency increases superoxide and endothelial dysfunction during inflammation.
- Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice.
- Gene transfer of endothelial nitric oxide synthase but not Cu/Zn superoxide dismutase restores nitric oxide availability in the SHRSP.
Schools
U Of Chgo Div Of Bio Sci Pritzker Sch Of Med
University Chicago Hosps
Procedures Preformed
- Cardiac Imaging
- Cardiac Myocardial Perfusion Imaging
- Chest CT (incl. Heart and Lungs)
- Tilt Testing or Cardiac Event Monitors
Conditions Treated
- Aortic Aneurysm
- Aortic Valve Disease
- Arrhythmias (incl. Atrial Fibrillation)
- Cardiomegaly
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Doctors Specialties
- Cardiology
Accepted Insurances
Awards
- Elected Member
Education
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University of Iowa Hospitals and Clinics -
University of Chicago -
University of Chicago Pritzker School of Medicine
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1982692505 |
| Last Name Of The Provider | HEISTAD |
| First Name Of The Provider | DONALD |
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