Professor, Pathology, Stanford University Medical Center
Pathology
Dr. Edgar G. Engleman, MD
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Edgar Engleman practices Pathology. He went to Columbia University College of Physicians & Surgeons. Columbia University College of Physicians & Surgeons is one of the top medical schools in the US. Columbia University College of Physicians & Surgeons is ranked 8/52 in Research/PrimaryCare. He received 1 awards: "Elected Member". Dr. Edgar G. Engleman is also published. He has 101 publications published. The lastest publication: "Human skin cells synthesize HLA-DR molecules of the same charge and molecular weight as those synthesized by autologous lymphocytes.'
Publications
- Tumor-binding antibodies and tumor immunity.
- Invariant natural killer T cells in lupus patients promote IgG and IgG autoantibody production.
- Detection of intestinal cancer by local, topical application of a quenched fluorescence probe for cysteine cathepsins.
- A Three-Gene Assay for Monitoring Immune Quiescence in Kidney Transplantation.
- B-1a lymphocytes attenuate insulin resistance.
- Treatment of 4T1 Metastatic Breast Cancer with Combined Hypofractionated Irradiation and Autologous T-Cell Infusion.
- Depletion of inflammatory dendritic cells with anti-CD209 conjugated to saporin toxin.
- Immune correlates of talactoferrin alfa in biopsied tumor of relapsed/refractory metastatic non-small cell lung cancer patients.
- Th17 cells induce Th1-polarizing monocyte-derived dendritic cells.
- Cd14 SNPs regulate the innate immune response.
- Heterogeneous distribution and transmembrane signaling properties of lymphocyte function-associated antigen (LFA-1) in human lymphocyte subsets.
- Evidence that cytotoxic lymphocytes alter and traverse allogeneic endothelial cell monolayers.
- Message amplification phenotyping (MAPPing): a technique to simultaneously measure multiple mRNAs from small numbers of cells.
- A subset of human rosetted lymphocytes contains previously unidentified histamine.
- Identification of protein intermediates in the processing of the p55 HIV-1 gag precursor in cells infected with recombinant vaccinia virus.
- Activation of HLA-restricted EBV-specific cytotoxic T cells does not require CD4+ (helper) T cells or exogenous cytokines.
- Pharmacologic effects of autacoids on subsets of T cells. Regulation of expression/function of histamine-2 receptors by a subset of suppressor cells.
- Responses of subpopulations of human helper T cells to autacoids.
- Human T cell leukemia virus-I-associated T-suppressor cell inhibition of erythropoiesis in a patient with pure red cell aplasia and chronic T gamma-lymphoproliferative...
- T cell regulatory disturbances in the rheumatic diseases.
- Immune mechanisms in transfusion.
- Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.
- Regulation of the immune response in man by a cascade of interactive T lymphocytes.
- Generation of antigen receptor-specific suppressor T cell clones in man.
- Immunoglobulin production in the autologous MLR: target of the suppressor-amplifier circuit.
- T cell defect in lepromatous leprosy is reversible in vitro in the absence of exogenous growth factors.
- Induction of antigen-specific suppressor T cells during acute infection with Toxoplasma gondii.
- Phenotypic identification of suppressor-effector, suppressor-amplifier and suppressor-inducer T cells of B cell differentiation in man.
- Immunoregulatory T lymphocytes in man. Cell surface molecules involved in their function.
- Alloantigen-specific cytotoxic clones bearing the alpha,beta T cell antigen receptor but not CD4 or CD8 molecules.
- Natural killer lines and clones with apparent antigen specificity.
- Abnormal T suppressor cell function in juvenile rheumatoid arthritis.
- Granulocyte-macrophage colony-stimulating factor promotes differentiation and survival of human peripheral blood dendritic cells in vitro.
- Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex.
- Identification of an immunostimulating protein from Mycobacterium leprae.
- Effective vaccination of mice against leprosy bacilli with subunits of Mycobacterium leprae.
- Molecular variants of the HLA-B27 antigen in healthy individuals and patients with spondylarthropathies.
- Expression and processing of human immunodeficiency virus type 1 gag and pol genes by cells infected with a recombinant vaccinia virus.
- Evidence for involvement of the gamma, delta T cell antigen receptor in cytotoxicity mediated by human alloantigen-specific T cell clones.
- Differences in surface phenotype between cytolytic and non-cytolytic CD4+ T cells. MHC class II-specific cytotoxic T lymphocytes lack Leu 8 antigen and express CD2 in ...
- Natural killer (NK)-like cytotoxic activity of allospecific T cell receptor-gamma,delta+ T cell clones. Distinct receptor-ligand interactions mediate NK-like and allos...
- Role of CD4 in normal immunity and HIV infection.
- Evidence that T cell activation is required for HIV-1 entry in CD4+ lymphocytes.
- CD4 molecules are associated with the antigen receptor complex on activated but not resting T cells.
- Variables affecting T-lymphocyte subsets in a volunteer blood donor population.
- Defective cell-mediated immunity in leprosy: failure of T cells from lepromatous leprosy patients to respond to Mycobacterium leprae is associated with defective expre...
- Lymphocyte subsets and surface molecules in man.
- Human monoclonal antibodies neutralizing varicella-zoster virus.
- Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein.
- Human monoclonal anti-T cell antibody from a patient with juvenile rheumatoid arthritis.
- pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane.
- Discrimination of viable and non-viable cells using propidium iodide in two color immunofluorescence.
- Lymphocyte subsets differentially induce class II human leukocyte antigens on allogeneic microvascular endothelial cells.
- Human monoclonal antibodies to Rh0(D).
- Immunoregulatory T cell circuits in man. Identification of a distinct T cell subpopulation of the helper/inducer lineage that amplifies the development of alloantigen-...
- Immunoregulatory T cells in man. Histamine-induced suppressor T cells are derived from a Leu 2+ (T8+) subpopulation distinct from that which gives rise to cytotoxic T ...
- Functional characterization of human T lymphocyte subsets distinguished by monoclonal anti-leu-8.
- Human T-cell subpopulations distinguished by monoclonal antibodies.
- Antigen-specific suppressor T lymphocytes in man make use of the same set of surface molecules as do cytolytic T lymphocytes: roles of Leu-2/T8, Leu-4/T3, Leu-5/T11, L...
- The immunohistology of the persistent generalized lymphadenopathy syndrome (PGL).
- Phenotypic and functional characterization of lymphocytes that bind human microvascular endothelial cells in vitro. Evidence for preferential binding of natural killer...
- Evidence for an association between CD8 molecules and the T cell receptor complex on cytotoxic T cells.
- Immunoglobulin secretion in the human autologous mixed leukocyte reaction. Definition of a suppressor-amplifier circuit using monoclonal antibodies.
- Dissection of immunoregulatory subpopulations of T lymphocytes within the helper and suppressor sublineages in man.
- Hodgkin's disease susceptibility: linkage to the HLA locus demonstrated by a new concordance method.
- Immunoregulatory T cell circuits in man. Alloantigen-primed inducer T cells activate alloantigen-specific suppressor T cells in the absence of the initial antigenic st...
- Correlation of functional properties of human lymphoid cell subsets and surface marker phenotypes using multiparameter analysis and flow cytometry.
- Reduced in vitro immune responses of purified human Leu-3 (helper/induced phenotype) cells after total lymphoid irradiation.
- Suppression of pokeweed mitogen-stimulated immunoglobulin production in patients with rheumatoid arthritis after treatment with total lymphoid irradiation.
- Immunoregulatory T cell circuits in man--an overview of recent advances.
- Functional and quantitative alterations in T lymphocyte subpopulations in acute toxoplasmosis.
- Human T lymphocyte proliferation induced by a pan-T monoclonal antibody (anti-Leu 4): heterogeneity of response is a function of monocytes.
- Changes in T-cell subsets in patients with rheumatoid arthritis treated with total lymphoid irradiation.
- Analysis of HLA-B27 antigen with monoclonal antibodies.
- Functional characteristics of human T-cell subpopulations distinguished by a monoclonal antibody.
- Autologous mixed lymphocyte reaction in patients with Hodgkin's disease. Evidence for a T cell defect.
- Ia antigen on peripheral blood mononuclear leukocytes in man. II. Functional studies of HLA-DR-positive T cells activated in mixed lymphocyte reactions.
- Antibodies to membrane structures that distinguish suppressor/cytotoxic and helper T lymphocyte subpopulations block the mixed leukocyte reaction in man.
- Induction of immunoglobulin-secreting cells in the allogeneic mixed leukocyte reaction: regulation by helper and suppressor lymphocyte subsets in man.
- Treatment of intractable rheumatoid arthritis with total lymphoid irradiation.
- Activation of human T lymphocyte subsets: helper and suppressor/cytotoxic T cells recognize and respond to distinct histocompatibility antigens.
- Induction of immunoglobulin secreting cells in the human autologous mixed leukocyte reaction: regulation by helper and suppressor lymphocyte subsets defined with monoc...
- Immunochemical variants of HLA-B27.
- A simplified new method for HLA-DR typing using the TM1 monoclonal antibody.
- Blocking of human T lymphocyte functions by anti-Leu-2 and anti-Leu-3 antibodies: differential inhibition of proliferation and suppression.
- Selective enrichment of human epidermal cell subpopulations using monoclonal antibodies.
- Use of the fluorescence-activated cell sorter to quantitate and enrich for subpopulations of human skin cells.
- In vitro responses of human lymphocytes to synthetic polypeptide antigens.
- Inhibition of a Langerhans cell-mediated immune response by treatment modalities useful in psoriasis.
- Sustained improvement of intractable rheumatoid arthritis after total lymphoid irradiation.
- Inhibition of cell mediated immune responses by 8-methoxypsoralen and long-wave ultraviolet light: a possible explanation for the clinical effects of photoactivated ps...
- Ia antigen on peripheral blood mononuclear leukocytes in man. I. Expression, biosynthesis, and function of HLA-DR antigen non-T cells.
- Human skin cells synthesize HLA-DR molecules of the same charge and molecular weight as those synthesized by autologous lymphocytes.
- Efficacy of total lymphoid irradiation in intractable rheumatoid arthritis. A double-blind, randomized trial.
- Progress toward understanding self-tolerance.
- Maturational and functional diversity of human B lymphocytes delineated with anti-Leu-8.
- Incidence of myocardial infarction in patients with rheumatoid arthritis.
- Attitudes toward women physicians. A study of 500 clinic patients.
- Kinin-forming activity of human lymphocytes.
- Granulated sugar as treatment for hiccups in conscious patients.
Schools
Columbia University College of Physicians And Surgeons
University Calif Hospital
Doctors Specialties
- Internal Medicine
- Pathology
Accepted Insurances
Awards
- Elected Member
Education
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UCSF -
Columbia University College of Physicians & Surgeons
Hospital
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Stanford Health Care
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