Emeritus Professor of Medicine, pathology and Laboratory Medicine, The University of Texas health Science Center at Houston (retired from practice)
Rheumatology
Dr. Frank C. Arnett, MD
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Frank C. Arnett works in the field of Rheumatology. He went to medical school at University of Cincinnati College of Medicine. He received awards:"Top MD". Dr. Frank C. Arnett is a published doctor and has 64 publications published. The lastest was: 'Antinuclear antibody-negative systemic sclerosis.'
Publications
- Antinuclear antibody-negative systemic sclerosis.
- Major histocompatibility complex (MHC) class I and II alleles which confer susceptibility or protection in the Morphea in Adults and Children (MAC) cohort.
- Immunochip analysis identifies multiple susceptibility Loci for systemic sclerosis.
- Morphea in Adults and Children Cohort III: Nested Case-Control Study-The Clinical Significance of Autoantibodies in Morphea.
- Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility.
- Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study.
- Can Serum Surfactant Protein D or CC-Chemokine Ligand 18 Predict Outcome of Interstitial Lung Disease in Patients with Early Systemic Sclerosis?
- New insight on the Xq28 association with systemic sclerosis.
- Osteopontin in systemic sclerosis and its role in dermal fibrosis.
- IRF5 polymorphism predicts prognosis in patients with systemic sclerosis.
- Decreased catalytic function with altered sumoylation of DNA topoisomerase I in the nuclei of scleroderma fibroblasts.
- Cigarette smoking is not a risk factor for systemic sclerosis.
- DRB1*15 Allele Is a Risk Factor for PR3-ANCA Disease in African Americans.
- Anti-Fibrillarin Antibody in African American Patients with Systemic Sclerosis: Immunogenetics, Clinical Features, and Survival Analysis.
- Association of a functional IRF7 variant with systemic lupus erythematosus.
- Association study of ITGAM, ITGAX, and CD58 autoimmune risk loci in systemic sclerosis: results from 2 large European Caucasian cohorts.
- HLA-DRB1*0407 and *1304 are risk factors for scleroderma renal crisis.
- Toll-like receptor 3 upregulation by type I interferon in healthy and scleroderma dermal fibroblasts.
- Separate influences of birth order and gravidity/parity on the development of systemic sclerosis.
- Systemic sclerosis and lupus: points in an interferon-mediated continuum.
- HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: a genome-wide association study in Koreans with replication in North Americans.
- Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines.
- Clinical and genetic factors predictive of mortality in early systemic sclerosis.
- Ultraviolet radiation intensity predicts the relative distribution of dermatomyositis and anti-Mi-2 autoantibodies in women.
- Characterization of the inflammatory cells in ascending thoracic aortic aneurysms in patients with Marfan syndrome, familial thoracic aortic aneurysms, and sporadic an...
- Induction of interferon-alpha by scleroderma sera containing autoantibodies to topoisomerase I: association of higher interferon-alpha activity with lung fibrosis.
- Genetics and genomic studies in scleroderma (systemic sclerosis).
- CTGF polymorphism associated with systemic sclerosis.
- Differential dynamic properties of scleroderma fibroblasts in response to perturbation of environmental stimuli.
- Clinical, immunologic, and genetic features of familial systemic sclerosis.
- Pulmonary involvement in systemic sclerosis: associations with genetic, serologic, sociodemographic, and behavioral factors.
- Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus.
- Association of the PTPN22 R620W polymorphism with anti-topoisomerase I- and anticentromere antibody-positive systemic sclerosis.
- Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma.
- Is scleroderma an autoantibody mediated disease?
- HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis aut...
- A mariner with crippling arthritis and bleeding eyes.
- Attenuation of collagen production with small interfering RNA of SPARC in cultured fibroblasts from the skin of patients with scleroderma.
- Induction of apoptosis and fibrillin 1 expression in human dermal endothelial cells by scleroderma sera containing anti-endothelial cell antibodies.
- Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European A...
- Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clini...
- Monozygotic twins clinically discordant for scleroderma show concordance for fibroblast gene expression profiles.
- Autoantibodies to fibrillin-1 activate normal human fibroblasts in culture through the TGF-beta pathway to recapitulate the "scleroderma phenotype".
- Polymorphisms of endothelial nitric oxide synthase and angiotensin-converting enzyme in systemic sclerosis.
- Seasonal influence on the onset of idiopathic inflammatory myopathies in serologically defined groups.
- Spondyloarthritis: update on pathogenesis and management.
- Classification analysis of the transcriptosome of nonlesional cultured dermal fibroblasts from systemic sclerosis patients with early disease.
- Small interfering RNA inhibition of SPARC attenuates the profibrotic effect of transforming growth factor beta1 in cultured normal human fibroblasts.
- Genetic signatures of pre-expansion bottleneck in the Choctaw population of Oklahoma.
- Fibrillin 1 abnormalities in dermal fibroblast cultures from first-degree relatives of patients with systemic sclerosis (scleroderma).
- Genomic absence of the gene encoding T cell receptor Vbeta7.2 is linked to the presence of autoantibodies in Sjögren's syndrome.
- Examination of the possible role of biologically relevant genes around FBN1 in systemic sclerosis in the Choctaw population.
- Genome-wide association study for regions of systemic sclerosis susceptibility in a Choctaw Indian population with high disease prevalence.
- Autoantibodies to the epidermal growth factor receptor in systemic sclerosis, lupus, and autoimmune mice.
- Linkage and interaction of loci on 1q23 and 16q12 may contribute to susceptibility to systemic lupus erythematosus.
- Polymorphisms beta2-glycoprotein I: phospholipid binding and multimeric structure.
- Association of novel polymorphisms with the expression of SPARC in normal fibroblasts and with susceptibility to scleroderma.
- Familiality and co-occurrence of clinical features of systemic lupus erythematosus.
- Mutations of bone morphogenetic protein receptor type II are not found in patients with pulmonary hypertension and underlying connective tissue diseases.
- The molecular basis of complete complement C4A and C4B deficiencies in a systemic lupus erythematosus patient with homozygous C4A and C4B mutant genes.
- The complex genetics of scleroderma.
- The genetics of systemic sclerosis.
- Right bundle branch block: a predictor of mortality in early systemic sclerosis.
Schools
University Of Cincinnati College Of Medicine
Johns Hopkins Hospital
Doctors Specialties
- Rheumatology
Accepted Insurances
Awards
- Top MD
Education
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Johns Hopkins University -
University of Cincinnati College of Medicine
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