Professor of Neurological Surgery, Johns Hopkins University School of Medicine; A Earl Walker Professor, Director of Functional Neurosurgery.
Neurosurgery
Dr. Frederick Lenz, MD
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Frederick Lenz practices Neurosurgery. He received awards:"CMS Meaningful Use Stage 1 Certification", "Whos Who in Medicine and Healthcare", "Fellow (FAANS)" and "Grass Award". Doctor Frederick Lenz, MD is a published MD. He published 99 publications, including: 'The role of the thalamus and basal ganglia in parkinsonian tremor.' He is registered with Medicare and accepts Medicare payments.
Publications
- EMG activity and neuronal activity in the internal globus pallidus (GPi) and their interaction are different between hemiballismus and apomorphine induced dyskinesias ...
- Painful cutaneous laser stimuli induce event-related gamma-band activity in the lateral thalamus of humans.
- Adaptation of high-gamma responses in human auditory association cortex.
- Thalamic post-inhibitory bursting occurs in patients with organic dystonia more often than controls.
- EEG analysis reveals widespread directed functional interactions related to a Painful cutaneous laser stimulus.
- Reliability of early cortical auditory gamma-band responses.
- Pelvic organ prolapse: does the postoperative course of mesh-repair surgery differ in elderly women when compared with younger patients?
- Characterization of cortical spreading depression by imaging of intrinsic optical signals.
- Chapter 59 Neurosurgical treatment of Pain.
- HIV-associated primary CNS lymorbidity and utility of Brain biopsy.
- Central post-stroke Pain: a challenge for the scientist and the clinician.
- Electromyographic response to Displacement of different forelimb joints in the squirrel monkey.
- The effect of cortical lesions on the electromyographic response to joint Displacement in the squirrel monkey forelimb.
- Co-stimulation with an olfactory stimulus increases arousal responses to trigeminal stimulation.
- Thalamic mechanisms of chest Pain in the absence of cardiac pathology.
- Cross-correlation analysis of thalamic neurons and EMG activity in parkinsonian tremor.
- Distribution and response evoked by microstimulation of thalamus nuclei in patients with dystonia and tremor.
- Neural activities of tactile cross-modal working memory in humans: an event-related potential study.
- Human Brain capillary endothelium: modulation of K+ efflux and K+, Ca2+ uptake by endothelin.
- Nitric oxide modulates endothelin 1-induced Ca2+ mobilization and cytoskeletal F-actin filaments in human cerebromicrovascular endothelial cells.
- Human Brain capillary endothelium: 2-arachidonoglycerol (endocannabinoid) interacts with endothelin-1.
- Ablative therapy for movement disorders. Thalamotomy for Parkinson's Disease.
- Effective response evoked by microstimulation of thalamus nuclei in patients with tremor.
- Studies of properties of "Pain Networks" as predictors of targets of stimulation for treatment of Pain.
- Evidence that excitatory amino acids mediate afferent input to the primate somatosensory thalamus.
- ET-1- and NO-mediated signal transduction pathway in human Brain capillary endothelial cells.
- Square-wave action dystonia in Parkinson's Disease.
- Somatosensory stimulus entrains spindle oscillations in the thalamic VPL nucleus in barbiturate anesthetized rats.
- Tremor-frequency (3-6 Hz) activity in the sensorimotor arm representation of the internal segment of the globus pallidus in patients with Parkinson''s Disease.
- Thalamic single neuron and electromyographic activities in patients with dystonia.
- Facilitation of responses to AMPA but not kainate by cyclothiazide in primate somatosensory thalamus.
- Irregularity distinguishes limb tremor in cervical dystonia from essential tremor.
- Pallidotomy for hemiballismus: efficacy and characteristics of neuronal activity.
- Responses of primate spinomesencephalic tract cells to intradermal capsaicin.
- Recordings of abnormal activity in patients with deafferentation and central Pain.
- The role of feedBack in the tremor frequency activity of tremor cells in the ventral nuclear group of human thalamus.
- Selection of the optimal lesion site for the relief of parkinsonian tremor on the basis of spectral analysis of neuronal firing patterns.
- Thalamic neuronal activity correlated with essential tremor.
- Thalamic microelectrode recording and microstimulation in central and deafferentation Pain.
- Thalamic stimulation and recording in patients with deafferentation and central Pain.
- Endothelin-1 and nitric oxide affect human cerebromicrovascular endothelial responses and signal transduction.
- Analysis of synchrony demonstrates that the presence of "Pain networks" prior to a noxious stimulus can enable the perception of Pain in response to that stimulus.
- Human "memories" can be evoked by stimulation of the lateral temporal cortex after ipsilateral medial temporal lobe resection.
- Fear conditioning is associated with dynamic directed functional interactions between and within the human amygdala, hippocampus, and frontal lobe.
- Adrenergic mediation of TNF alpha-stimulated ICAM-1 expression on human Brain microvascular endothelial cells.
- Microelectrode techniques in localization of stereotactic targets.
- Modulation of somatosensory event-related potential components in a tactile-visual cross-modal task.
- Stereotactic thalamotomy in the treatment of essential tremor of the upper extremity: reassessment including a blinded measure of outcome.
- Physiological changes in primate somatosensory thalamus induced by deafferentation are dependent on the spinal funiculi that are sectioned and time following Injury.
- Characteristics of the bursting pattern of action potentials that occurs in the thalamus of patients with central Pain.
- Abnormal single-unit activity recorded in the somatosensory thalamus of a quadriplegic patient with central Pain.
- Neuronal activity in the region of the thalamic principal sensory nucleus (ventralis caudalis) in patients with Pain following amputations.
- Pallidal activity during dystonia: somatosensory reorganisation and changes with severity.
- Internal pallidal neuronal activity during mild drug-related dyskinesias in Parkinson's Disease: decreased firing rates and altered firing patterns.
- Methods for microstimulation and reCording of single neurons and evoked potentials in the human central nervous system.
- Role of the thalamus in parkinsonian tremor: evidence from studies in patients and primate models.
- Single unit analysis of the human ventral thalamic nuclear group: correlation of thalamic "tremor cells" with the 3-6 Hz component of parkinsonian tremor.
- Thalamic single-unit activity occurring in patients with hemidystonia.
- Distribution of cardiovascular related cells within the human thalamus.
- Plasticity of Pain-related neuronal activity in the human thalamus.
- The role of the thalamus and basal ganglia in parkinsonian tremor.
- Single-neuron analysis of human thalamus in patients with intention tremor and other clinical signs of cerebellar Disease.
- Transient unilateral hearing loss induced by electrocortical stimulation.
- Pain sensitivity alterations as a function of lesion location in the parasylvian cortex.
- Single-unit analysis of the human ventral thalamic nuclear group: somatosensory responses.
- Functional plasticity in primate somatosensory thalamus following chronic lesion of the ventral lateral Spinal cord.
- Statistical prediction of the optimal site for thalamotomy in parkinsonian tremor.
- A population of cells in the human thalamic principal sensory nucleus respond to Painful mechanical stimuli.
- Pain and temperature encoding in the human thalamic somatic sensory nucleus (Ventral caudal): inhibition-related bursting evoked by somatic stimuli.
- A Painful cutaneous laser stimulus evokes responses from single neurons in the human thalamic principal somatic sensory nucleus ventral caudal (Vc).
- Reorganization of somatic sensory function in the human thalamus after stroke.
- Responses of neurons in the region of human thalamic principal somatic sensory nucleus to mechanical and thermal stimuli graded into the Painful range.
- Mental arithmetic leads to multiple Discrete changes from baseline in the firing patterns of human thalamic neurons.
- Spontaneous low threshold spike bursting in awake humans is different in different lateral thalamic nuclei.
- Psychophysics of CNS Pain-related activity: binary and analog channels and memory encoding.
- Amplitudes of laser evoked potential reCorded from primary somatosensory, parasylvian and medial frontal cortex are graded with stimulus intensity.
- Attention to a Painful cutaneous laser stimulus modulates electrocorticographic event-related desynchronization in humans.
- Sequential neural processes of tactile-visual crossmodal working memory.
- Painful laser stimuli induce directed functional interactions within and between the human amygdala and hippocampus.
- Attention to Painful cutaneous laser stimuli evokes directed functional connectivity between activity recorded directly from human Pain-related cortical structures.
- Endogenous and exogenous modulators of potentials evoked by a Painful cutaneous laser (LEPs).
- Cold stimuli evoke potentials that can be reCorded directly from parasylvian cortex in humans.
- Altered Pain and thermal sensation in subjects with isolated parietal and insular cortical lesions.
- Painful stimuli evoke potentials recorded from the medial temporal lobe in humans.
- Stimulation in the human somatosensory thalamus can reproduce both the affective and sensory dimensions of previously experienced Pain.
- Neurons in the area of human thalamic nucleus ventralis caudalis respond to Painful heat stimuli.
- Patterns of bursting occurring in thalamic cells during parkinsonian tremor.
- Microelectrode reCording and stimulation techniques during stereotactic procedures in the thalamus and pallidum.
- Reorganization of sensory modalities evoked by microstimulation in region of the thalamic principal sensory nucleus in patients with pain due to nervous system Injury.
- Transcortical sensory aphasia: revisited and revised.
- Different generators in human temporal-parasylvian cortex account for subdural laser-evoked potentials, auditory-evoked potentials, and event-related potentials.
- Reorganization in the cutaneous core of the human thalamic principal somatic sensory nucleus (Ventral caudal) in patients with dystonia.
- Microelectrode studies of normal organization and plasticity of human somatosensory thalamus.
- Pain-related evoked potentials from parasylvian cortex in humans.
- Transient inhibition of responses to thermal stimuli of Spinal sensory tract neurons in monkeys during sensitization by intradermal capsaicin.
- Correlation of effects of general anesthetics on somatosensory neurons in the primate thalamus and cortical EEG power.
- Cortical representation of Pain: functional characterization of nociceptive areas near the lateral sulcus.
- Thalamic single neuron activity in patients with dystonia: dystonia-related activity and somatic sensory reorganization.
Schools
University Of Toronto Faculty Of Medicine
Wellesley Hospital
University Toronto
Procedures Preformed
- Craniectomy, Craniotomy, Surgery of Skull Base, Neuroendoscopy
- Deep Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Brain Stimulation
- Neurostimulation
- Neurostimulation, Spinal
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Conditions Treated
- Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Brain Aneurysm
- Background: yellow;'>Background: yellow;'>Background: yellow;'>Background: yellow;'>Brain Injury
- Cerebral Hemorrhage
- CerebroSpinal Fluid Leak (CSF Leak)
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Doctors Specialties
- Neurosurgery
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Whos Who in Medicine and Healthcare
- Fellow (FAANS)
- Grass Award
Hospital
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Johns Hopkins Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1215977004 |
| Last Name Of The Provider | LENZ |
| First Name Of The Provider | FREDERICK |
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