Physician

Nephrology

George Naff is an expert in the field of Nephrology. He went to University of Virginia School of Medicine. Doctor George B. Naff, MD has written publications. He has 37 publications published with PubMed. The lastest publication is: 'Unique C1 inhibitor dysfunction in a kindred without angioedema. I. A mutant C1 INH that inhibits C1-s but not C1-r.'

Publications

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• THE MACROMOLECULAR NATURE OF THE FIRST COMPONENT OF HUMAN COMPLEMENT.
• Chromatographic resolution of the first component of human complement into three activities.
• Studies on antibacterial factors in mammalian tissues and fluids. III. Serum bactericidin levels for Bacillus subtilis in myocardial infarction, pneumonia and other di...
• Studies on antibacterial factors in mammalian tissues and fluids. II. Cofactor requirements of a serum bactericidin for Bacillus subtilis.
• Unique C1 inhibitor dysfunction in a kindred without angioedema. I. A mutant C1 INH that inhibits C1-s but not C1-r.
• Blood group A immunodeterminants on human red cells differ in biologic activity and sensitivity to alpha-N-acetylgalactosaminidase.
• Inhibition of zymosan-induced alternative complement pathway activation by concanavalin A.
• The rabbit properdin system: I. Identification of a new factor and purification of rabbit properdin.
• The enzymatic nature of C''1r. Conversion of C''1s to C''1 esterase and digestion of amino acid esters by C''1r.
• Glomerular deposition of properdin in acute and chronic glomerulonephritis with hypocomplementemia.
• Decreased properdin activity in acute glomerulonephritis.
• Deficiency of C1r in human serum. Effects on the structure and function of macromolecular C1.
• Complement as a mediator of inflammation in acute gouty arthritis. II. Biological activities generated from complement by the interaction of serum complement and sodiu...
• Properdin--its biologic importance.
• Complement as a mediator of inflammation in acute gouty arthritis. I. Studies on the reaction between human serum complement and sodium urate crystals.
• The effect of complement depletion by cobra venom factor on delayed hypersensitivity reactions.
• The role of c''1q, cations, and ionic strength in the formation of C''1 esterase.
• The conversion of C''IS to C''1 esterase by plasmin and trypsin.
• The inhibition of plasmin, plasma kallikrein, plasma permeability factor, and the C''1r subcomponent of the first component of complement by serum C''1 esterase inhibi...
• Decreased properdin activity in Swiss-type lymphopenic agammaglobulinemia.
• Terminal complement component deficiencies and rheumatic disease: development of a rheumatic syndrome and anticomplementary activity in a patient with complete C6 defi...
• Immune complexes and complement abnormalities in patients with cystic fibrosis. Increased mortality associated with circulating immune complexes and decreased function...
• Alternative pathway complement activation induces reductions in effective hepatic blood flow.
• Metabolism of C4 and linkage analysis in a kindred with hereditary incomplete C4 deficiency.
• Complement activation in peritonitis. Association with hepatic and renal perfusion abnormalities. First place winner: Conrad Jobst award.
• Systemic complement activation produces hemodynamic changes characteristic of sepsis.
• Allopurinol and lodoxamide in complement-induced hepatic ischemia.
• Visceral perfusion abnormalities following complement activation. Clues to the mediators of organ ischemia in trauma and sepsis. First place winner: Conrad Jobst Award.
• Complement depletion alters the systemic and visceral hemodynamic response to endotoxemia.
• Contribution of toxic oxygen intermediates to complement-induced reductions in effective hepatic blood flow.
• Complement-mediated hemodynamic depression in the early postburn period.
• Serum IgG antibodies to C1q in hypocomplementemic urticarial vasculitis syndrome.
• Chemical mediators of inflammation in acute gouty arthritis.
• Activation of protein mediators of inflammation and evidence for endotoxemia in Borrelia recurrentis infection.
• Quantitative measurement of properdin in normal human serum by electroimmunoassay and single radial immunodiffusion.
• Prevention of hyperacute kidney rejection of decomplementation using purified cobra venom factor.

Schools

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• University Of Virginia School Of Medicine

Doctors Specialties

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• Nephrology

Accepted Insurances

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Education

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• Case Western Reserve University - University Hospitals
• University of Virginia School of Medicine

Hospital

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• University Hospitals Case Medical Center

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