Physician
Oncology
Dr. Ivor Royston, MD
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Ivor Royston, MD works in the field of Oncology. He studied medicine at Johns Hopkins University School of Medicine. Johns Hopkins University School of Medicine is a top medical college. Johns Hopkins University School of Medicine has a rank of 3 in research and a 29 in primary care He received 1 awards: "Elected Member". Dr. Ivor Royston has written publications. He has 92 publications published with PubMed. The lastest paper is: 'Combination of transforming growth factor beta antisense and interleukin-2 gene therapy in the murine ovarian teratoma model.'
Publications
- Interleukin 2 gene therapy of colorectal carcinoma with autologous irradiated tumor cells and genetically engineered fibroblasts: a Phase I study.
- Combination of transforming growth factor beta antisense and interleukin-2 gene therapy in the murine ovarian teratoma model.
- Antigen-specific IgG responses from naive human splenocytes: in vitro priming followed by antigen boost in the SCID mouse.
- Gene therapy approaches to enhance antitumor immunity.
- Radioimmunotherapy of relapsed B-cell lymphoma with yttrium 90 anti-idiotype monoclonal antibodies.
- Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy.
- Comparison of gene therapy with interleukin-2 gene modified fibroblasts and tumor cells in the murine CT-26 model of colorectal carcinoma.
- Cytokine gene therapy with interleukin-2-transduced fibroblasts: effects of IL-2 dose on anti-tumor immunity.
- Interleukin-2 gene therapy in a patient with glioblastoma.
- Injection of colon carcinoma patients with autologous irradiated tumor cells and fibroblasts genetically modified to secrete interleukin-2 (IL-2): a phase I study.
- Phenotypic markers and BCL-1 gene rearrangements in B-cell chronic lymphocytic leukemia: a Cancer and Leukemia Group B study.
- The effects of postinduction intensification treatment with cytarabine and daunorubicin in adult acute lymphocytic leukemia: a prospective randomized clinical trial by...
- Production of antigen-specific human monoclonal antibodies from in vitro-primed human splenocytes.
- Radioimmunotherapy of human B-cell lymphoma with 90Y-conjugated antiidiotype monoclonal antibody.
- Unique subset of thymic epithelial cells defined by the expression of a novel neuroendocrine antigen.
- Morphologic and cytochemical characterization of adult lymphoid leukemias which express myeloid antigen.
- Immunophenotyping in the diagnosis and classification of acute lymphoblastic leukemia.
- Genetically stable human hybridomas secreting tumor-reactive human monoclonal IgM.
- IDEC-C2B8: results of a phase I multiple-dose trial in patients with relapsed non-Hodgkin's lymphoma.
- IDEC-C2B8 (Rituximab) anti-CD20 monoclonal antibody therapy in patients with relapsed low-grade non-Hodgkin's lymphoma.
- In vitro priming of human lymphocytes. II. Induction of antigen-specific IgG responses by repeated antigen stimulation.
- In vitro priming of human lymphocytes. I. IL-2 and IL-4 requirements.
- Gene therapy approval process.
- Factors affecting production of antibodies to prostate antigens by in vitro-primed human splenocytes.
- Colony-forming assay for circulating chronic lymphocytic leukemia cells.
- Monoclonal antibodies to a human T-cell antigen and Ia-like antigen in the characterization of lymphoid leukemia.
- Comparative density of the human T-cell antigen T65 on normal peripheral blood T cells and chronic lymphocytic leukemia cells.
- Human T cell antigens defined by monoclonal antibodies: the 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukemia cells bearing surface ...
- Utility of monoclonal antibodies in the immunologic phenotyping of acute lymphoblastic leukemia.
- Development of a rapid microELISA assay for screening hybridoma supernatants for murine monoclonal antibodies.
- Human T-cell antigens defined by monoclonal antibodies. Absence of T65 on committed myeloid and erythroid progenitors.
- Murine monoclonal antibody therapy in two patients with chronic lymphocytic leukemia.
- Use of immunoglobulin light chain analysis to detect bone marrow involvement in B-cell neoplasms.
- Extracellular paraprotein globules in a patient with monoclonal gammopathy.
- Structural characterization of the human T cell surface antigen (p67) isolated from normal and neoplastic lymphocytes.
- Alterations of peripheral blood B-lymphocyte populations in plasma cell disorders.
- Lack of radioimmunodetection and complications associated with monoclonal anticarcinoembryonic antigen antibody cross-reactivity with an antigen on circulating cells.
- Characterization of a monoclonal antibody that reacts with activated/proliferating cells and subsets of leukemia cells.
- Membranous nephropathy associated with an unusual phenotype of chronic lymphocytic leukemia.
- Alterations in cell surface phenotype of T- and B-cell chronic lymphocytic leukemia cells following in vitro differentiation by phorbol ester.
- Chronic lymphocytic leukemia and other chronic lymphoid proliferations: surface marker phenotypes and clinical correlations.
- UC 729-6, a human lymphoblastoid B-cell line useful for generating antibody-secreting human-human hybridomas.
- A novel cell surface antigen (T305) found in increased frequency on acute leukemia cells and in autoimmune disease states.
- Chronic lymphocytic leukemia progenitor cells carry the antigens T65, BA-1, and Ia.
- Characterization of a monoclonal antibody that reacts with an activation antigen on human B cells: reactions on mitogen-stimulated blood lymphocytes and cells of norma...
- An enzyme immunofiltration assay useful for detecting human monoclonal antibody.
- Therapy of chronic lymphocytic leukemia and cutaneous T-cell lymphoma with T101 monoclonal antibody.
- Induction of in vitro and in vivo antigenic modulation by the anti-human T-cell monoclonal antibody T101.
- In vivo immune restoration in advanced cancer patients after administration of thymosin fraction 5 or thymosin alpha 1.
- Membrane antigen on Epstein--Barr virus-infected human B cells recognized by a monoclonal antibody.
- Non-cross-resistant chemotherapy and consolidation radiotherapy for small cell carcinoma of the lung.
- Extensive disease small cell carcinoma of the lung: trial of non-cross resistant chemotherapy and consolidation radiotherapy.
- Establishment and characterization of an Epstein-Barr virus-negative lymphoma B-cell from a patient with a diffuse large cell lymphoma.
- Plasma calcitonin as a marker of disease activity in patients with small cell carcinoma of the lung.
- Immunoincompetence in cancer patients. Assessment by in vitro stimulation tests and quantification of lymphocyte subpopulations.
- A human monoclonal antibody reactive with human prostate.
- Human autologous mixed lymphocyte reactivity is primarily specific for xenoprotein determinants adsorbed to antigen-presenting cells during rosette formation with shee...
- Applications of monoclonal antibodies in cancer therapy.
- Comparative mortality of childhood leukemia and lymphoma among the immigrants and native born in Israel.
- Autologous human B and T lymphoblastoid cell lines.
- Letter: Herpesvirus type 2 infection and cervical carcinoma.
- Antibody to genital herpes simplex virus: association with cervical atypia and carcinoma in situ.
- Genital herpes virus findings in relation to cervical neoplasia.
- Immunofluorescent detection of herpesvirus antigens in exfoliated cells from human cervical carcinoma.
- The association of genital herpesvirus with cervical atypia and carcinoma in situ.
- Failure of cultured human T-cell lymphoid lines to stimulate in mixed leukocyte culture.
- Letter: Epstein-Barr virus and infectious mononucleosis.
- Cell lines from human patients: who owns them? A case report.
- Monoclonal antibody immunocytology: potential applications for staging and monitoring malignant disease activity.
- Applications and limitations of peripheral blood lymphocyte immunoglobulin light chain analysis in the evaluation of non-Hodgkin's lymphoma.
- The use of monoclonal antibodies and flow cytometry to detect peripheral blood and bone marrow involvement of a diffuse, poorly differentiated lymphoma.
- Kinetics of protein synthesis inactivation in human T-lymphocytes by selective monoclonal antibody-ricin conjugates.
- Adult acute lymphoblastic leukemia phenotypes defined by monoclonal antibodies.
- Phase II trial of thymosin fraction 5 and thymosin alpha 1.
- Monoclonal antibodies to purified ricin A-chain: production and properties.
- Clinical importance of myeloid antigen expression in adult acute lymphoblastic leukemia.
- Strategies for the design and use of tumor-reactive human monoclonal antibodies.
- Epidermal growth factor receptor expression in human lung carcinomas defined by a monoclonal antibody.
- Establishment of a human B-cell tumor in athymic mice.
- Elevated serum chromogranin A concentrations in small-cell lung carcinoma.
- Shared idiotypes expressed by human B-cell lymphomas.
- Expression of shared idiotypes in chronic lymphocytic leukemia and small lymphocytic lymphoma.
- Infection of human and rhesus lymphoblastoid cells with Herpesvirus macaca.
- Electron-microscopic study of Herpesvirus macaca in human fibroblasts.
- Homogeneous antibodies directed against human cell surface antigens: I. The mouse spleen fragment culture response to T and B cell lines derived from the same individual.
- Cell mediated immunity during infectious mononucleosis to Epstein-Barr virus associated antigens.
- Cell-mediated immunity in acute infectious mononucleosis.
- Cell-mediated immunity to Epstein-Barr-virus-transformed lymphoblastoid cells in acute infectious mononucleosis.
- In vitro lymphocyte dysfunction in Hodgkin''s disease.
- Morphologic and cytochemical comparison of human lymphoblastoid T-cell and B-cell lines: light and electron microscopy.
- Public policy symposium: the legal, ethical, and economic impact of patient material used for product development in the biomedical industry.
Schools
Johns Hopkins University School of Medicine
Doctors Specialties
- Medical Oncology
- Oncology
Accepted Insurances
Awards
- Elected Member
Education
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Stanford University -
Johns Hopkins University School of Medicine
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