Professor of Pediatrics, Indiana University
Pediatric Hematology & Oncology
Dr. James M. Croop, MD
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James M. Croop practices Pediatric Hematology & Oncology. He studied medicine at Perelman School of Medicine at the University of Pennsylvania. He over the years received 4 awards: "America's Top Doctors", "America's Top Doctors for Cancer", "Indianapolis Monthly" and "Whos Who in Medicine and Healthcare". James M. Croop has written publications. He has 57 publications published with PubMed. The lastest publication is: 'Evolutionary relationships among ABC transporters.'
Publications
- Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial.
- Germline p53 mutation presenting as synchronous tumors.
- Treatment, outcome, and cost of care in children with idiopathic Thrombocytopenic purpura.
- Gene therapy for fanconi Anemia.
- Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster Cells.
- Response of myogenic and fibrogenic Cells to cytochalasin B and to colcemid. I. Light microscope observations.
- Effects of cytochaslasin B and colcemide on myogenic cultures.
- A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps.
- Pseudocyesis in an adolescent patient. Case report and radiologic analysis.
- The response of chicken embryo dermal fibroblasts to cytochalasin B is altered by Rous sarcoma virus-induced Cell transformation.
- Effects of Cytochalasin-B and colcimide on Cells in muscle cultures.
- TPA reversibly blocks the differentiation of chick myogenic, chondrogenic, and melanogenic Cells.
- Effects of 12-O-tetradecanoyl-phorbol-13-acetate on Myofibril integrity and Ca2+ content in developing myotubes.
- Selective effects of phorbol 12-myristate 13-acetate on myofibrils and 10-nm filaments.
- Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins.
- Monoclonal antibody to an external epitope of the human mdr1 P-glycoprotein.
- Role of P-glycoprotein in dolastatin 10 resistance.
- P-glycoprotein multidrug resistance and Cancer.
- Phosphatidylcholine and phosphatidylethanolamine behave as substrates of the human MDR1 P-glycoprotein.
- Packaging Cell line DNA contamination of vector supernatants: implication for laboratory and clinical research.
- Women's sense of well-being before and after hysterectomy.
- Differential location of different types of intermediate-sized filaments in various Tissues of the chicken embryo.
- A pilot study of dose-intensified procarbazine, CCNU, vincristine for poor prognosis Brain tumors utilizing fibronectin-assisted, retroviral-mediated modification of C...
- Gene therapy in the treatment of Fanconi Anemia, a progressive bone marrow failure syndrome.
- Clinical course of postthrombotic syndrome in children with history of venous thromboembolism.
- CD8+ T cells activated during the course of murine Acute myelogenous leukemia elicit therapeutic responses to late B7 vaccines after cytoreductive treatment.
- Isolation and characterization of a mammalian homolog of the Drosophila white gene.
- Expression of Drosophila melanogaster P-glycoproteins is associated with ATP channel activity.
- Irradiated B7-1 transduced primary Acute myelogenous leukemia (AML) cells can be used as therapeutic vaccines in murine AML.
- Functional imaging of multidrug-resistant P-glycoprotein with an organotechnetium complex.
- P-glycoprotein structure and evolutionary homologies.
- Characterization of multidrug resistance P-glycoprotein transport function with an organotechnetium cation.
- Genetics of multidrug resistance: relationship of a cloned gene to the complete multidrug resistant phenotype.
- Intermediate-size filaments: changes in synthesis and distribution in Cells of the myogenic and neurogenic lineages.
- Arizona hinshawii osteomyelitis associated with a pet snake.
- Chromosome-mediated gene transfer of multidrug resistance.
- mdr2 encodes P-glycoprotein expressed in the bile canalicular membrane as determined by isoform-specific antibodies.
- Benzquinamide inhibits P-glycoprotein mediated drug efflux and potentiates antiCancer agent cytotoxicity in multidrug resistant cells.
- Differences among 100-A filamentilament subunits from different Cell types.
- The gene encoding multidrug resistance is induced and expressed at high levels during pregnancy in the secretory epithelium of the uterus.
- Genetics of multidrug resistance.
- Isolation and expression of a complementary DNA that confers multidrug resistance.
- P-glycoproteins encoded by mdr 1b in murine gravid uterus and multidrug resistant tumor Cell lines are differentially glycosylated.
- The three mouse multidrug resistance (mdr) genes are expressed in a Tissue-specific manner in normal mouse Tissues.
- Isolation and characterization of Drosophila multidrug resistance gene homologs.
- Multidrug resistance gene expression is controlled by steroid hormones in the secretory epithelium of the uterus.
- Mobilization and collection of peripheral blood CD34+ cells from patients with Fanconi Anemia.
- Characterization of functional assays of multidrug resistance P-glycoprotein transport activity.
- Large-scale mobilization and isolation of CD34+ Cells from normal donors.
- Evolutionary relationships among ABC transporters.
- Multidrug resistance gene expression correlates with progesterone production in dehydroepiandrosterone-induced polycystic and equine chorionic gonadotropin-stimulated ...
- Characterization of P-glycoprotein transport and inhibition in vivo.
- Gene immunotherapy in murine Acute myeloid leukemia: granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compare...
- Gene therapy with B7.1 and GM-CSF vaccines in a murine AML model.
- Population pharmacokinetics of intravenous ondansetron in oncology and surgical patients aged 1-48 months.
- Phase I and pharmacokinetic study of gefitinib in children with refractory solid tumors: a Children''s Oncology Group Study.
Schools
University Of Pennsylvania School Of Medicine
Children39s Hospital Of Philadelphia
Chldns Hospital Med Center
Conditions Treated
- Acute Leukemia
- Adrenal Gland Cancer
- Anemia
- Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
- View All
Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Awards
- America's Top Doctors
- America's Top Doctors for Cancer
- Indianapolis Monthly
- Whos Who in Medicine and Healthcare
Education
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Boston Children's Hospital -
Children's Hospital of Philadelphia -
Perelman School of Medicine at the University of Pennsylvania
Hospital
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Riley Hospital for Children at Indiana University Health
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