Professor of Surgery, University Iowa College of Medicine
General Surgery
Dr. James R. Howe V, MD
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Doctor James R. Howe V, MD works in the field of General Surgery. He went to medical school at University of Vermont College of Medicine. He has 5 awards "CMS Meaningful Use Stage 1 Certification", "Best Doctors in America", "America's Top Doctors", "Top Doctors" and "Fellow". James Howe is also a published doctor. He has 80 paper published. The most recent paper is: The risk of gastrointestinal carcinoma in familial juvenile polyposis. James Howe is registered with Medicare.
Publications
- A practical method to determine the site of unknown primary in metastatic Neuroendocrine tumors.
- RABL6A promotes G1-S phase progression and pancreatic Neuroendocrine tumor cell proliferation in an Rb1-dependent manner.
- Gene expression accurately distinguishes Liver metastases of small bowel and pancreas neuroendocrine tumors.
- Medical management of metastatic medullary thyroid Cancer.
- Limitations of somatostatin scintigraphy in primary small bowel Neuroendocrine tumors.
- Elevated pancreatic polypeptide levels in pancreatic Neuroendocrine tumors and diabetes mellitus: causation or association?
- GIPR expression in gastric and duodenal Neuroendocrine tumors.
- Complications and survival associated with operative procedures in patients with unresectable pancreatic head adenoCarcinoma.
- Erratum to: The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in Neuroendocrine tumours.
- Overexpression of membrane proteins in primary and metastatic gastroIntestinal neuroendocrine tumors.
- Gastric inhibitory polypeptide receptor (GIPR) is a promising target for imaging and therapy in Neuroendocrine tumors.
- Preoperative evaluation of thyroglossal Duct cysts: children versus adults-is there a difference?
- Do giant Parathyroid adenomas represent a distinct clinical entity?
- Translational research in endocrine surgery.
- Discriminating Pheochromocytomas from Other Adrenal Lesions: The Dilemma of Elevated Catecholamines.
- The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in Neuroendocrine tumours.
- Neuroendocrine Tumors Arising in Meckel's Diverticula: Frequency of Advanced Disease Warrants Aggressive Management.
- A comprehensive assessment of transfusion in elective pancreatectomy: risk factors and complications.
- BMPR1A mutations in juvenile polyposis affect cellular localization.
- The Value of Preoperative Imaging in Small Bowel Neuroendocrine Tumors.
- Invasion in follicular thyroid Cancer cell lines is mediated by EphA2 and pAkt.
- Differentiation of small bowel and pancreatic Neuroendocrine tumors by gene-expression profiling.
- Risk of subsequent primary thyroid Cancer after another malignancy: latency trends in a population-based study.
- Germline mutations in SMAD4 disrupt bone morphogenetic protein signaling.
- Comparison of clinicopathologic factors in 122 patients with resected pancreatic and ileal Neuroendocrine tumors from a single institution.
- Juvenile polyposis and other Intestinal polyposis syndromes with microdeletions of chromosome 10q22-23.
- SP1 regulates the transcription of BMPR1A.
- Discovery of SMAD4 promoters, transcription factor binding sites and deletions in juvenile polyposis patients.
- Surveillance and intervention after thyroid lobectomy.
- PET-CT scans in recurrent or persistent differentiated thyroid Cancer: is there added utility beyond conventional imaging?
- Discovery of the BMPR1A promoter and germline mutations that cause juvenile polyposis.
- Development of a highly sensitive and specific carboxy-terminal human pancreastatin assay to monitor Neuroendocrine tumor behavior.
- Juvenile Polyposis Syndrome
- Expansion of a cell population expressing stem cell markers in parathyroid Glands from patients with hyperparathyroidism.
- Determinants of survival in patients with calciphylaxis: a multivariate Analysis.
- When is prophylactic thyroidectomy indicated for patients with the RET codon 609 mutation?
- Juvenile polyps have gastric differentiation with MUC5AC expression and downregulation of CDX2 and SMAD4.
- The rate of germline mutations and large deletions of SMAD4 and BMPR1A in juvenile polyposis.
- Altered expression of iron regulatory genes in cirrhotic human Livers: clues to the cause of hemosiderosis?
- ECM1 expression in thyroid Tumors--a comparison of real-time RT-PCR and IHC.
- Hamartomatous polyposis syndromes.
- Role for limited neck exploration in young adults with apparently sporadic primary Hyperparathyroidism.
- A family with two consecutive nonsense mutations in BMPR1A causing juvenile polyposis.
- Minimally invasive parathyroidectomy and preoperative MIBI scans: correlation of Gland weight and preoperative PTH.
- ENG mutations in MADH4/BMPR1A mutation negative patients with juvenile polyposis.
- RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid Carcinoma.
- Hereditary colorectal Cancer-part II.
- Hereditary colon Cancer--part I.
- Genetic conditions associated with Intestinal juvenile polyps.
- The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations.
- Challenging colonic polyposis pedigrees: differential diagnosis, surveillance, and management concerns.
- Role of the DPC4 tumor suppressor gene in adenocarcinoma of the ampulla of Vater: Analysis of 140 cases.
- Germline SMAD4 or BMPR1A mutations and phenotype of juvenile polyposis.
- Combined urinary and fecal diversion using a no bowel anastomosis technique.
- Common deletion of SMAD4 in juvenile polyposis is a mutational hotspot.
- Small bowel sarcoma: analysis of survival from the National Cancer Data Base.
- Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.
- The American College of Surgeons Commission on Cancer and the American Cancer Society. Adenocarcinoma of the small bowel: review of the National Cancer Data Base, 1985...
- Direct genetic testing for Smad4 mutations in patients at risk for juvenile polyposis.
- The risk of gastrointestinal Carcinoma in familial juvenile polyposis.
- K-ras mutation in adenomas and Carcinomas of the ampulla of vater.
- Mutations in the SMAD4/DPC4 gene in juvenile polyposis.
- A gene for familial juvenile polyposis maps to chromosome 18q21.1.
- The molecular genetics of pancreatic Cancer.
- DNA exTraction from paraffin-embedded tissues using a salting-out procedure: a reliable method for PCR amplification of archival material.
- The genetics of colorectal Cancer.
- Needle localization Breast biopsy: a model for multidisciplinary quality assurance.
- Prevalence of pheochromocytoma and Hyperparathyroidism in multiple endocrine neoplasia type 2A: results of long-term follow-up.
- Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC.
- Development of a sequence-tagged site for the centromere of chromosome 10: its use in cytogenetic and physical mapping.
- A 1.5-megabase yeast artificial chromosome contig from human chromosome 10q11.2 connecting three genetic loci (RET, D10S94, and D10S102) closely linked to the MEN2A lo...
- Isolation of YAC clones from the pericentromeric region of chromosome 10 and development of new genetic markers linked to the multiple endocrine neoplasia type 2A gene.
- Improved predictive test for MEN2, using flanking dinucleotide repeats and RFLPs.
- Presymptomatic identification of carriers of the multiple endocrine neoplasia type 2A gene using flanking DNA markers.
- A new RFLP marker D5S348 maps to 5p14.3-15.2, between D5S60 (CRI-R535) and HPRTP2.
- The molecular biology of Parathyroid disease.
- A new RFLP marker D12S54 maps between F8VWF and KRAS2 on human chromosome 12p.
- Esophageal Cancer in a family with hamartomatous tumors and germline PTEN frameshift and SMAD7 missense mutations.
- Serous CystadenoCarcinoma of the Pancreas: Clinical Features and Management of a Rare Tumor.
Schools
Univ Of Vt Coll Of Med
Barnes Jewish Hospital
Barnes Hospital Wash University
Meml Sloan Kettering Cancer Center
Procedures Preformed
- Adrenalectomy
- Anoscopy With Removal of Anal Tumor
- Appendectomy, Laparoscopic
- Appendectomy, Open
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Conditions Treated
- Abdominal Pain
- Adrenal Gland Cancer
- Anal and Rectal Cancer
- Appendicitis
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Doctors Specialties
- General Surgery
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Best Doctors in America
- America's Top Doctors
- Top Doctors
- Fellow
Education
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Memorial Sloan-Kettering Cancer Center -
Washington University - Barnes-Jewish Hospital -
University of Vermont College of Medicine
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