Professor, Division of General Medical Sciences, Case Western Reserve University School of Medicine
Infectious Disease
Dr. James W. Kazura, MD
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Doctor James W. Kazura, MD is an expert in the field of Infectious Disease. He researched medicine at The Ohio State University College of Medicine. He received 1 awards: "Elected Member". James W. Kazura is a published doctor. He published 101 publications, including: 'Absence of ivermectin-associated excess deaths.'
Publications
- Efficacy, Safety, and Pharmacokinetics of Coadministered Diethylcarbamazine, Albendazole, and Ivermectin for Treatment of Bancroftian Filariasis.
- More Progress in Eliminating Transmission of Onchocerca volvulus and Wuchereria bancrofti in the Americas: A Portent of Global Eradication.
- Association of symptoms and severity of rift valley Fever with genetic polymorphisms in human innate immune pathways.
- Factors associated with severe human rift valley Fever in sangailu, garissa county, kenya.
- Effect of transmission intensity and age on subclass antibody responses to Plasmodium falciparum pre-erythrocytic and blood-stage antigens.
- Density-Dependent Blood Stage Plasmodium falciparum Suppresses Malaria Super-Infection in a Malaria Holoendemic Population.
- Potential for Autoimmune Pathogenesis of Rift Valley Fever Virus Retinitis.
- Humoral and cellular immunity to Plasmodium falciparum merozoite surface protein 1 and protection from infection with blood-stage parasites.
- Population Genetics of the Filarial Worm Wuchereria bancrofti in a Post-treatment Region of Papua New Guinea: Insights into Diversity and Life History.
- Multiplex Assay for Species Identification and Monitoring of Insecticide Resistance in Anopheles punctulatus Group Populations of Papua New Guinea.
- Research challenges and gaps in malaria knowledge in Papua New Guinea.
- Antibodies to Plasmodium falciparum Erythrocyte-binding Antigen-175 Are Associated With Protection From Clinical Malaria.
- Reduction in Acute Filariasis Morbidity during a Mass Drug Administration Trial to Eliminate Lymphatic Filariasis in Papua New Guinea.
- Age-Related Differences in Naturally Acquired T Cell Memory to Plasmodium falciparum Merozoite Surface Protein 1.
- Back to the future: the American Society of Tropical Medicine and Hygiene, its journal and the continuing commitment to global health.
- Higher-dose, more frequent treatment of Wuchereria bancrofti.
- Advances in Rift Valley fever research: insights for disease prevention.
- Allele specificity of gamma interferon responses to the carboxyl-terminal region of Plasmodium falciparum merozoite surface protein 1 by Kenyan adults with naturally a...
- Molecular-based assay for simultaneous detection of four Plasmodium spp. and Wuchereria bancrofti infections.
- TLR9 polymorphisms are associated with altered IFN-gamma levels in children with cerebral malaria.
- Stability of interferon-gamma and interleukin-10 responses to Plasmodium falciparum liver stage antigen 1 and thrombospondin-related adhesive protein immunodominant ep...
- Low prevalence of antibodies to preerythrocytic but not blood-stage Plasmodium falciparum antigens in an area of unstable malaria transmission compared to prevalence i...
- Determinants of success in national programs to eliminate lymphatic filariasis: a perspective identifying essential elements and research needs.
- Discordant patterns of genetic variation at two chloroquine resistance loci in worldwide populations of the malaria parasite Plasmodium falciparum.
- Antibodies to pre-erythrocytic Plasmodium falciparum antigens and risk of clinical malaria in Kenyan children.
- Mass drug administration trial to eliminate lymphatic filariasis in Papua New Guinea: changes in microfilaremia, filarial antigen, and Bm14 antibody after cessation.
- Global eradication of lymphatic filariasis: the value of chronic disease control in parasite elimination programmes.
- Antibody-mediated growth inhibition of Plasmodium falciparum: relationship to age and protection from parasitemia in Kenyan children and adults.
- The impact of repeated rounds of mass drug administration with diethylcarbamazine plus albendazole on bancroftian filariasis in Papua New Guinea.
- A polymerase chain reaction/ligase detection reaction fluorescent microsphere assay to determine Plasmodium falciparum MSP-119 haplotypes.
- Exposure to holoendemic malaria results in suppression of Epstein-Barr virus-specific T cell immunosurveillance in Kenyan children.
- Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, o...
- Efficacy of single-dose diethylcarbamazine compared with diethylcarbamazine combined with albendazole against Wuchereria bancrofti infection in Papua New Guinea.
- Reduced Plasmodium vivax erythrocyte infection in PNG Duffy-negative heterozygotes.
- Prenatal malaria immune experience affects acquisition of Plasmodium falciparum merozoite surface protein-1 invasion inhibitory antibodies during infancy.
- Changing patterns of Plasmodium blood-stage infections in the Wosera region of Papua New Guinea monitored by light microscopy and high throughput PCR diagnosis.
- Prenatal T cell immunity to Wuchereria bancrofti and its effect on filarial immunity and infection susceptibility during childhood.
- Stability of interferon-gamma and interleukin-10 responses to Plasmodium falciparum liver stage antigen-1 and thrombospondin-related adhesive protein in residents of a...
- Mass chemotherapy options to control lymphatic filariasis: a systematic review.
- Antibodies to Plasmodium falciparum antigens vary by age and antigen in children in a malaria-holoendemic area of Kenya.
- Correlation of high levels of antibodies to multiple pre-erythrocytic Plasmodium falciparum antigens and protection from infection.
- Distinct Th1- and Th2-Type prenatal cytokine responses to Plasmodium falciparum erythrocyte invasion ligands.
- Gamma interferon responses to Plasmodium falciparum liver-stage antigen 1 and thrombospondin-related adhesive protein and their relationship to age, transmission inten...
- Evidence that invasion-inhibitory antibodies specific for the 19-kDa fragment of merozoite surface protein-1 (MSP-1 19) can play a protective role against blood-stage ...
- Mathematical modelling and the control of lymphatic filariasis.
- Glycophorin C (Gerbich antigen blood group) and band 3 polymorphisms in two malaria holoendemic regions of Papua New Guinea.
- Interferon-gamma responses to Plasmodium falciparum liver-stage antigen-1 and merozoite-surface protein-1 increase with age in children in a malaria holoendemic area o...
- Spatial variation of Anopheles-transmitted Wuchereria bancrofti and Plasmodium falciparum infection densities in Papua New Guinea.
- Influence of maternal filariasis on childhood infection and immunity to Wuchereria bancrofti in Kenya.
- Antibodies to the Plasmodium falciparum antigens circumsporozoite protein, thrombospondin-related adhesive protein, and liver-stage antigen 1 vary by ages of subjects ...
- Sensitivity and specificity of ultrasound detection and risk factors for filarial-associated hydroceles.
- Plasmodium falciparum erythrocyte invasion through glycophorin C and selection for Gerbich negativity in human populations.
- Mass treatment to eliminate filariasis in Papua New Guinea.
- Malaria infections are randomly distributed in diverse holoendemic areas of Papua New Guinea.
- Lymphocyte proliferation and antibody responses to Plasmodium falciparum liver-stage antigen-1 in a highland area of Kenya with seasonal variation in malaria transmiss...
- Acquired immune responses to Plasmodium falciparum merozoite surface protein-1 in the human fetus.
- Sequential modelling of the effects of mass drug treatments on anopheline-mediated lymphatic filariasis infection in papua new Guinea.
- Impact of untreated bednets on prevalence of Wuchereria bancrofti transmitted by Anopheles farauti in Papua New Guinea.
- Towards eliminating lymphatic filariasis in Papua New Guinea: impact of annual single-dose mass treatment on transmission of Wuchereria bancrofti in East Sepik Province.
- Brugia malayi: acquired resistance to microfilariae in BALB/c mice correlates with local Th2 responses.
- The lymphokine eosinophil stimulation promoter and human schistosomiasis mansoni.
- Stage-specific antibody-dependent eosinophil-mediated destruction of Trichinella spiralis.
- Deficient production of the lymphokine eosinophil stimulation promoter in chemically induced and mutation diabetes mellitus in mice.
- Human monocyte-lymphocyte interaction and its enhancement by levamisole.
- The effect of diethylcarbamazine in a murine model of Brugia malayi microfilaraemia.
- Modulation of murine cytokine responses to mycobacterial antigens by helminth-induced T helper 2 cell responses.
- Ivermectin and human lymphatic filariasis.
- Trichinosis of the central nervous system.
- The association of the glycophorin C exon 3 deletion with ovalocytosis and malaria susceptibility in the Wosera, Papua New Guinea.
- Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America.
- Efficient discovery of immune response targets by cyclical refinement of QSAR models of peptide binding.
- Ecologic and biologic determinants of filarial antigenemia in bancroftian filariasis in Papua New Guinea.
- Migration and dispersal of lymphatic filariasis in Papua New Guinea.
- Transmission intensity determines lymphocyte responsiveness and cytokine bias in human lymphatic filariasis.
- Application of a polymerase chain reaction-ELISA to detect Wuchereria bancrofti in pools of wild-caught Anopheles punctulatus in a filariasis control area in Papua New...
- Influence of age and HLA type on interferon-gamma (IFN-gamma) responses to a naturally occurring polymorphic epitope of Plasmodium falciparum liver stage antigen-1 (LS...
- Differential expression of the duffy antigen receptor for chemokines according to RBC age and FY genotype.
- Cytokine responses to Plasmodium falciparum liver-stage antigen 1 vary in rainy and dry seasons in highland Kenya.
- Random distribution of mixed species malaria infections in Papua New Guinea.
- Treatment with ivermectin reduces the high prevalence of scabies in a village in Papua New Guinea.
- Emergence of FY*A(null) in a Plasmodium vivax-endemic region of Papua New Guinea.
- Mass treatment with ivermectin for filariasis control in Papua New Guinea: impact on mosquito survival.
- Acute disease episodes in a Wuchereria bancrofti-endemic area of Papua New Guinea.
- Helminth- and Bacillus Calmette-Guérin-induced immunity in children sensitized in utero to filariasis and schistosomiasis.
- Absence of ivermectin-associated excess deaths.
- Interleukin-12 suppresses filaria-induced pulmonary eosinophilia, deposition of major basic protein and airway hyperresponsiveness.
- Parental infection confounded with local infection intensity as risk factors for childhood microfilaraemia in bancroftian filariasis.
- Biology of malarial liver stages: implications for vaccine design.
- The role of eosinophils and neutrophils in helminth-induced keratitis.
- B cell sensitization to helminthic infection develops in utero in humans.
- Randomised community-based trial of annual single-dose diethylcarbamazine with or without ivermectin against Wuchereria bancrofti infection in human beings and mosquit...
- T-cell immunity to peptide epitopes of liver-stage antigen 1 in an area of Papua New Guinea in which malaria is holoendemic.
- Pleomorphism of stromal eosinophils in murine experimental onchocercal keratitis.
- Transmission intensity and its relationship to infection and disease due to Wuchereria bancrofti in Papua New Guinea.
- B7-2 requirement for helminth-induced granuloma formation and CD4 type 2 T helper cell cytokine expression.
- In utero exposure to helminth and mycobacterial antigens generates cytokine responses similar to that observed in adults.
- IL-12 exacerbates helminth-mediated corneal pathology by augmenting inflammatory cell recruitment and chemokine expression.
- Onchocerca volvulus-mediated keratitis: cytokine production by IL-4-deficient mice.
- Modulation of polymorphonuclear leukocyte microbicidal activity and oxidative metabolism by fibrinogen degradation products D and E.
- Platelet-neutrophil interaction: modulation of the inflammatory response.
Schools
Case Western Reserve University School of Medicine
Doctors Specialties
- Hematology
- Infectious Disease
Accepted Insurances
Awards
- Elected Member
Education
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University of Pennsylvania Health System -
Case Western Reserve University - University Hospitals -
The Ohio State University College of Medicine
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