Professor, Ophthalmology, Perelman School of Medicine at the University of Pennsylvania

Ophthalmology

Joan O'Brien practices Ophthalmology. She went to medical school at Geisel School of Medicine at Dartmouth. Geisel School of Medicine at Dartmouth is ranked 37 in research and 29 in primary care medicine She has 33 awards "America's Top Doctors", "Member", "Women in Ophthalmology Suzanne Veronneau-Troutman Award for Mentoring", "Best Doctors in America", "Best Cancer Doctor in America", "PennMedicine Innovation Accelerator Program Award", "Certificate of Appreciation as Community Internship Sponsor", "CMS Meaningful Use Stage 1 Certification", "The Raymond C. Cook, M.D. Distinguished Visiting Professor Award", "Certificate of Appreciation as Preceptor", "Senior Achievement Award", "Work-Life Achievement Award", "Bressler Prize Nominee", "Academic Senate Distinction in Teaching Award Nominee", "Certificate of Recognition for Dedicated Service", "National Medical Association Ophthalmology Award for Excellence in Medical Students and Ophthalmology Residents Education - Rabb-Venable Ophthalmology Award", "Inducted Member", "Jesse H. Neal Best Single Issue Award for Excellence in Business Journalism", "Chancellor's Award for the Advancement of Women Nominee", "Physician Scientist Award Inaugural Year Recipient", "Kaiser Award Nominee for Excellence in Medical Student Education", "Champion of Diversity, Office of Affirmative Action, Equal Opportunity and Diversity", "Young Investigator Award", "Honor Award", "Alpha Omega Alpha", "Dean's Medal, Outstanding Graduating Senior", "Syvertson Fellowship, Outstanding Junior Student", "Warden Fellowship", "Class Valedictorian", "Phi Beta Kappa", "Catlin Award, Classical Studies", "Highest Departmental Honors, Psychology" and "Woolsey Prize, Religious Studies". Dr. Joan M. O'Brien is a published doctor and has 39 publications published. The lastest was: 'Primary Open-Angle Glaucoma in Individuals of African Descent: A Review of Risk Factors.'

Publications

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• Primary Open-Angle Glaucoma in Individuals of African Descent: A Review of Risk Factors.
• The primary open-angle african american glaucoma genetics study: baseline demographics.
• Trends in female representation in published ophthalmology literature, 2000-2009.
• Uveal melanoma trapped in the temple of doom.
• Intra-arterial Chemotherapy for Advanced Retinoblastoma: Is the Time Right for a Prospective Clinical Trial?
• Adult ovarian Retinoblastoma genomic profile.
• Optical coherence tomography for Retinal metastasis with unknown primary tumor.
• Fundus image fusion in EYEPLAN software: an evaluation of a novel technique for ocular melanoma radiation treatment planning.
• Trilateral Retinoblastoma: potentially curable with intensive chemotherapy.
• Differential microRNA-34a expression and tumor suppressor function in Retinoblastoma cells.
• Frontiers in the management of Retinoblastoma.
• Subconjunctival nanoparticle carboplatin in the treatment of murine Retinoblastoma.
• Poliosis as a manifestation of conjunctival melanoma.
• Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of Retinoblastoma.
• The future promise and the current reality of genetic prognostication in patients with uveal melanoma.
• Subconjunctival topotecan in fibrin sealant in the treatment of transgenic murine Retinoblastoma.
• Choroidal detachment following the use of tamsulosin (Flomax).
• Estimates of ocular and visual retention following treatment of extra-large uveal melanomas by proton beam radiotherapy.
• Successful treatment of intraocularly invasive conjunctival squamous cell carcinoma with proton beam therapy.
• 3D MRI-based tumor delineation of ocular melanoma and its comparison with conventional techniques.
• Pathology and genetics of primary central nervous system and intraocular lymphoma.
• Subconjunctival carboplatin in fibrin sealant in the treatment of transgenic murine Retinoblastoma.
• Desmoplastic small round cell tumor: a potentially lethal Neoplasm manifesting in the orbit with associated visual symptoms.
• Cyclosporin a inhibits calcineurin/nuclear factor of activated T-cells signaling and induces apoptosis in Retinoblastoma cells.
• Retinoblastoma: animal models.
• Geographic disparities in diagnostic screening for metastatic uveal melanoma.
• External beam radiation "salvage" therapy in transgenic murine Retinoblastoma.
• Rapid identification of germline mutations in Retinoblastoma by protein truncation testing.
• Posterior pole tumor update.
• Atypical Retinoblastoma presentations: a challenge for the treating ophthalmologist.
• Research: the track record justifies expanded support.
• Three-dimensional high-resolution magnetic resonance imaging of ocular and orbital malignancies.
• Hyperfractionated external beam radiation therapy in the treatment of murine transgenic Retinoblastoma.
• Masquerade syndromes: malignancies mimicking inflammation in the eye.
• Optic disc and cup segmentation from color fundus photograph using graph cut with priors.
• Retinoblastoma and hypochondroplasia: a case report of two germline mutations arising simultaneously.
• High-resolution 3D T2-weighted fast spin echo: new applications in the orbit.
• Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi.

Schools

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• Dartmouth Medical School

• Beth Israel Hospital

• Mass Eye and Ear Infirm

• Uc San Francisco Med Center

Conditions Treated

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• Benign Neoplasm of Choroid
• Benign Neoplasm of Eye
• Malignant Neoplasm of Eye
• Nystagmus
• View All

Doctors Specialties

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• Ophthalmology

Accepted Insurances

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Awards

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• America's Top Doctors
• Member
• Women in Ophthalmology Suzanne Veronneau-Troutman Award for Mentoring
• Best Doctors in America
• Best Cancer Doctor in America
• PennMedicine Innovation Accelerator Program Award
• Certificate of Appreciation as Community Internship Sponsor
• CMS Meaningful Use Stage 1 Certification
• The Raymond C. Cook, M.D. Distinguished Visiting Professor Award
• Certificate of Appreciation as Preceptor
• Senior Achievement Award
• Work-Life Achievement Award
• Bressler Prize Nominee
• Academic Senate Distinction in Teaching Award Nominee
• Certificate of Recognition for Dedicated Service
• National Medical Association Ophthalmology Award for Excellence in Medical Students and Ophthalmology Residents Education - Rabb-Venable Ophthalmology Award
• Inducted Member
• Jesse H. Neal Best Single Issue Award for Excellence in Business Journalism
• Chancellor's Award for the Advancement of Women Nominee
• Physician Scientist Award Inaugural Year Recipient
• Kaiser Award Nominee for Excellence in Medical Student Education
• Champion of Diversity, Office of Affirmative Action, Equal Opportunity and Diversity
• Young Investigator Award
• Honor Award
• Alpha Omega Alpha
• Dean's Medal, Outstanding Graduating Senior
• Syvertson Fellowship, Outstanding Junior Student
• Warden Fellowship
• Class Valedictorian
• Phi Beta Kappa
• Catlin Award, Classical Studies
• Highest Departmental Honors, Psychology
• Woolsey Prize, Religious Studies

Education

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• Massachusetts Eye & Ear Infirmary
• Beth Israel Deaconess Medical Center
• Geisel School of Medicine at Dartmouth

Hospital

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• Hospital of the University of Pennsylvania
• Penn Presbyterian Medical Center

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