Molecular Neuroimaging, LLC
Radiology
Dr. John P. Seibyl, MD
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John P. Seibyl, MD is an expert in the field of Radiology. He studied medicine at Case Western Reserve University School of Medicine. Doctor John P. Seibyl, MD is a published MD as well. He has 63 publications published. The latest was: Preclinical properties and human in vivo assessment of 123I-ABC577 as a novel SPECT agent for imaging amyloid-.
Publications
- Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial.
- Preclinical properties and human in vivo assessment of 123I-ABC577 as a novel SPECT agent for imaging amyloid-β.
- Age dependence of brain β-amyloid deposition in Down syndrome: An [18F]florbetaben PET study.
- Adenosine 2A Receptor Occupancy by Tozadenant and Preladenant in Rhesus Monkeys.
- Imaging prodromal Parkinson disease: The Parkinson Associated Risk Syndrome Study.
- The Phosphodiesterase 10 Positron Emission Tomography Tracer, [18F]MNI-659, as a Novel Biomarker for Early Huntington Disease.
- In Vivo Assessment and Dosimetry of 2 Novel PDE10A PET Radiotracers in Humans: 18F-MNI-659 and 18F-MNI-654.
- Individual-Reader Diagnostic Performance and Between-Reader Agreement in Assessment of Subjects with Parkinsonian Syndrome or Dementia Using 123I-Ioflupane Injection (...
- Longitudinal follow-up of SWEDD subjects in the PRECEPT Study.
- In Vivo Evaluation of 18F-MNI698: An 18F-Labeled Radiotracer for Imaging of Serotonin 4 Receptors in Brain.
- Whole-body biodistribution and dosimetry estimates of a novel radiotracer for imaging of serotonin 4 receptors in brain: [(18)F]MNI-698.
- A practical approach to remote longitudinal follow-up of Parkinson's disease: The FOUND study.
- Synthesis and biological evaluation of positron emission tomography radiotracers targeting serotonin 4 receptors in brain: [(18)F]MNI-698 and [(18)F]MNI-699.
- Changes in the cholinergic system between bipolar depression and euthymia as measured with [123I]5IA single photon emission computed tomography.
- Kinetic Modeling, Test-Retest, and Dosimetry of 123I-MNI-420 in Humans.
- Tibial Bone Lead, but Not Serum Polychlorinated Biphenyl, Concentrations Are Associated With Neurocognitive Deficits in Former Capacitor Workers.
- Kinetic analysis of the metabotropic glutamate subtype 5 tracer [(18)F]FPEB in bolus and bolus-plus-constant-infusion studies in humans.
- Sex-specific differences in GABA(A) -benzodiazepine receptor availability: relationship with sensitivity to pain and tobacco smoking craving.
- Imaging Changes in Synaptic Acetylcholine Availability in Living Human Subjects.
- In vivo evaluation of ¹²³ImZIENT as a SPECT radioligand for the serotonin transporter.
- The molecular basis of dopaminergic brain imaging in Parkinson's disease.
- Estimating the half-lives of PCB congeners in former capacitor workers measured over a 28-year interval.
- Pharmacokinetic modeling and [¹²³]5-IA-85380 single photon emission computed tomography imaging in baboons: optimization of dosing ...
- Decreased Beta(2)*-nicotinic acetylcholine receptor availability after chronic ethanol exposure in nonhuman primates.
- Quantification of smoking-induced occupancy of beta2-nicotinic acetylcholine receptors: estimation of nondisplaceable binding.
- Occupational exposure to PCBs reduces striatal dopamine transporter densities only in women: a beta-CIT imaging study.
- GABAA-benzodiazepine receptor availability in smokers and nonsmokers: relationship to subsyndromal anxiety and depression.
- Age-related decline in nicotinic receptor availability with [(123)I]5-IA-85380 SPECT.
- Dopamine and serotonin transporter availability during acute alcohol withdrawal: effects of comorbid tobacco smoking.
- 123I-5-IA-85380 SPECT imaging of nicotinic receptors in Alzheimer disease and mild cognitive impairment.
- beta2-Nicotinic acetylcholine receptor availability during acute and prolonged abstinence from tobacco smoking.
- Biomarkers for Parkinson's [corrected] disease: tools to assess Parkinson's disease onset and progression.
- Striatal dopamine transporters correlate with simple reaction time in elderly subjects.
- Single-photon emission computed tomography and positron emission tomography evaluations of patients with central motor disorders.
- 3,4-dihydroxy-6-[18f]-fluoro-L-phenylalanine positron emission tomography in patients with central motor disorders and in evaluation of brain and other tumors.
- 123I-5-IA-85380 SPECT imaging of nicotinic acetylcholine receptor availability in nonsmokers: effects of sex and menstrual phase.
- Optimized, automated striatal uptake analysis applied to SPECT brain scans of Parkinson's disease patients.
- Displacement of serotonin and dopamine transporters by venlafaxine extended release capsule at steady state: a [123I]2beta-carbomethoxy-3beta-(4-iodophenyl)-tropane si...
- [123I]5-IA-85380 SPECT imaging of beta2-nicotinic acetylcholine receptor availability in the aging human brain.
- Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers.
- Cryopreservable neutrophil surrogates: granule-poor, motile cytoplasts from polymorphonuclear leukocytes home to inflammatory lesions in vivo.
- Sex differences in diencephalon serotonin transporter availability in major depression.
- 123I-5-IA-85380 SPECT measurement of nicotinic acetylcholine receptors in human brain by the constant infusion paradigm: feasibility and reproducibility.
- Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smok...
- Chest radiograph as a triage tool in the imaging-based diagnosis of pulmonary embolism.
- Increased dopamine transporter availability associated with the 9-repeat allele of the SLC6A3 gene.
- Research applications of selected 123I-labeled neuroreceptor SPECT imaging ligands.
- Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors.
- (123I) beta-CIT and single-photon emission computed tomographic imaging vs clinical evaluation in Parkinsonian syndrome: unmasking an early diagnosis.
- Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder.
- Central serotonin transporter availability measured with [123I]beta-CIT SPECT in relation to serotonin transporter genotype.
- Benzodiazepine receptor distribution in severe intractable tinnitus.
- Technical overview of brain SPECT imaging: improving acquisition and processing of data.
- Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT.
- Increase in prefrontal cortex serotonin 2A receptors following estrogen treatment in postmenopausal women.
- Selective frontal, parietal, and temporal networks in generalized seizures.
- Imaging studies in movement disorders.
- Changes in human in vivo serotonin and dopamine transporter availabilities during chronic antidepressant administration.
- Unaltered dopamine transporter availability in adult attention deficit hyperactivity disorder.
- Age-related decline in dopamine transporters: analysis of striatal subregions, nonlinear effects, and hemispheric asymmetries.
- Association between Hoehn and Yahr, Mini-Mental State Examination, age, and clinical syndrome predominance and diagnostic effectiveness of ioflupane I 123 injection (D...
- Tauopathy PET and amyloid PET in the diagnosis of chronic traumatic encephalopathies: studies of a retired NFL player and of a man with FTD and a severe head injury.
Schools
Case Western Reserve University School of Medicine
Greenwich Hospital Assocs
Yale University School Of Med
Doctors Specialties
- Nuclear Medicine
- Psychiatry
- Radiology
Accepted Insurances
Education
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Yale-New Haven Hospital -
Case Western Reserve University School of Medicine
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