Professor, Medicine, UCSF School of Medicine
Internal Medicine
Dr. John V. Fahy, MD
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Doctor John V. Fahy, MD practices Internal Medicine. He has 1 awards "CMS Meaningful Use Stage 1 Certification". John Fahy is also published. He has 101 publications published. The lastest publication: "Neutrophil elastase and elastase-rich cystic fibrosis sputum degranulate human eosinophils in vitro.' John V. Fahy accepts Medicare.
Publications
- Oxidation increases mucin polymer cross-links to stiffen airway mucus gels.
- A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production.
- Lipoxin Generation is Related to Soluble Epoxide Hydrolase Activity in Severe Asthma.
- Asthma and the flu: a tricky two-step.
- Intelectin-1 is a prominent protein constituent of pathologic mucus associated with eosinophilic airway inflammation in asthma.
- Asthma: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.
- Type 2 immune responses in obese individuals with asthma.
- Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma.
- P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy.
- An integrated nano-scale approach to profile miRNAs in limited clinical samples.
- Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction.
- Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients.
- The airway epithelium as a regulator of th2 responses in asthma.
- The relevance of tick bites to the production of IgE antibodies to the mammalian oligosaccharide galactose-α-1,3-galactose.
- Gene expression patterns of Th2 inflammation and intercellular communication in asthmatic airways.
- Hexaphenylbenzene as a rigid template for the straightforward syntheses of "star-shaped" glycodendrimers.
- The H antigen at epithelial surfaces is associated with susceptibility to asthma exacerbation.
- Airway mucus function and dysfunction.
- Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma.
- Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma.
- Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease.
- Identifying clinical phenotypes of asthma: steps in the right direction.
- Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma.
- T-helper type 2-driven inflammation defines major subphenotypes of asthma.
- Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma.
- Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein.
- Eosinophilic and neutrophilic inflammation in asthma: insights from clinical studies.
- Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit.
- Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids.
- Characterizing mucous cell remodeling in cystic fibrosis: relationship to neutrophils.
- Epithelial mucin stores are increased in the large airways of smokers with airflow obstruction.
- Anti-IgE: lessons learned from effects on airway inflammation and asthma exacerbation.
- Induced sputum evaluation in microwave popcorn production workers.
- Dissecting asthma using focused transgenic modeling and functional genomics.
- Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma.
- Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression.
- Applying stereology to measure thickness of the basement membrane zone in bronchial biopsy specimens.
- Effects of individual self-management education on clinical, biological, and adherence outcomes in asthma.
- The role of mucus in fatal asthma.
- Goblet cell and mucin gene abnormalities in asthma.
- Airway remodeling in asthma.
- Systemic effect comparisons of six inhaled corticosteroid preparations.
- A role for neutrophils in asthma?
- Practical management of acute asthma in adults.
- Accumulation of BDCA1+ Dendritic Cells in Interstitial Fibrotic Lung Diseases and Th2-High Asthma.
- Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled...
- A trial of clarithromycin for the treatment of suboptimally controlled asthma.
- Tiotropium bromide step-up therapy for adults with uncontrolled asthma.
- Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma.
- The Predicting Response to Inhaled Corticosteroid Efficacy (PRICE) trial.
- Combination therapy with a long-acting beta-agonist and a leukotriene antagonist in moderate asthma.
- Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial.
- Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids.
- Daily versus as-needed corticosteroids for mild persistent asthma.
- beta-Adrenergic receptor polymorphisms and response to salmeterol.
- Airway tissue mast cells in persistent asthma: predictor of treatment failure when patients discontinue inhaled corticosteroids.
- Significant variability in response to inhaled corticosteroids for persistent asthma.
- Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma.
- Allergen challenge causes inflammation but not goblet cell degranulation in asthmatic subjects.
- Effect of aerosolized anti-IgE (E25) on airway responses to inhaled allergen in asthmatic subjects.
- Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression.
- Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects.
- Analysis of cellular and biochemical constituents of induced sputum after allergen challenge: a method for studying allergic airway inflammation.
- Similar RANTES levels in healthy and asthmatic airways by immunoassay and in situ hybridization.
- The effect of an anti-IgE monoclonal antibody on the early- and late-phase responses to allergen inhalation in asthmatic subjects.
- Epithelial desquamation in asthma: artifact or pathology?
- Fractional analysis of sequential induced sputum samples during sputum induction: evidence that different lung compartments are sampled at different time points.
- Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation.
- Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects.
- Effect of low-dose beclomethasone dipropionate on asthma control and airway inflammation.
- Low- and high-dose fluticasone propionate in asthma; effects during and after treatment.
- Predictors of late asthmatic response. Logistic regression and classification tree analyses.
- A qPCR-based metric of Th2 airway inflammation in asthma.
- The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma.
- Use of biological markers of airway inflammation to detect the efficacy of nurse-delivered asthma education.
- Relationship of epidermal growth factor receptors to goblet cell production in human bronchi.
- Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype.
- Controversies involving inhaled beta-agonists and inhaled corticosteroids in the treatment of asthma.
- Safety of one method of sputum induction in asthmatic subjects.
- Effect of an NK1 receptor antagonist (CP-99,994) on hypertonic saline-induced bronchoconstriction and cough in male asthmatic subjects.
- Effects of multiday exposure to ozone on airway inflammation as determined using sputum induction.
- Comparison of regularly scheduled with as-needed use of albuterol in mild asthma. Asthma Clinical Research Network.
- Comparison of two methods of collecting induced sputum in asthmatic subjects.
- Analysis of induced sputum after air and ozone exposures in healthy subjects.
- Mucus hypersecretion in bronchiectasis. The role of neutrophil proteases.
- Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: Clinical and biologic significance.
- Cellular and biochemical analysis of induced sputum from asthmatic and from healthy subjects.
- Airway inflammation and remodeling in asthma.
- Markers of mucus secretion and DNA levels in induced sputum from asthmatic and from healthy subjects.
- Neutrophil elastase and elastase-rich cystic fibrosis sputum degranulate human eosinophils in vitro.
- Use of mucin antibodies and cDNA probes to quantify hypersecretion in vivo in human airways.
- Targeting cytokines in asthma therapy: round one.
- Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma.
- Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: a randomized controlled trial.
- Effect of a single dose of the selectin inhibitor TBC1269 on early and late asthmatic responses.
- Quality control within the Asthma Clinical Research Network.
- Negative methacholine challenge tests in subjects who report physician-diagnosed asthma.
- A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness.
- Asthma: prevalence, pathogenesis, and prospects for novel therapies.
- Safety and reproducibility of sputum induction in asthmatic subjects in a multicenter study.
Schools
University College Dublin National University Of Ireland School Of Medicine and Medical Science
Doctors Specialties
- Internal Medicine
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
Hospital
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San Francisco General Hospital and Trauma Center -
UCSF Medical Center
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