Chief of Pediatric Allergy
Allergy & Immunology
Dr. Jonathan M. Spergel, MD
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Jonathan Spergel works in the field of Allergy & Immunology. He went to Icahn School of Medicine at Mount Sinai. Icahn School of Medicine at Mount Sinai is ranked 20 in research and 62 in primary care medicine He over the years received 22 awards: "Fellow (FAAAAI)", "Philadelphia Magazine", "America's Top Doctors", "Top Doctor", "Top Doc", "Top Docs", "Marquis Whos Who in America", "American Academy of Pediatrics", "Marquis Whos Who in Medicine and Healthcare 2004-07", "Top Physicians in America", "Fellow in American Academy of Allergy Asthma and Immunology", "Pennsylvania Allergy Education and Research Trust Award", "Ethel Brown Foerderer Award for Excellence", "Glaxo Wellcome Allergy Training Award", "Charles A. Janeway Scholarship", "Distinguished Accomplishment in the NIH Biomedical Sciences Research Award for Clinical Trainees Program", "Sigma Xi", "Magna cum laude in chemistry", "Castle Connollys Americas Top Doctor", "Stanley Weil Fellowship", "Super Doctor" and "NIH Medical Scientist Training Program". Jonathan M. Spergel is a published MD as well. He has 94 publications published. The latest was: Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized anti...
Publications
- Advances in the Treatment of Food Allergy: Sublingual and Epicutaneous Immunotherapy.
- Autophagy mediates epithelial cytoprotection in Eosinophilic oesophagitis.
- An allergist's perspective to the evaluation of Eosinophilic Esophagitis.
- Seasonal exacerbation of esophageal eosinophilia in children with Eosinophilic esophagitis and allergic rhinitis.
- The importance of TSLP in allergic disease and its role as a potential therapeutic target.
- Health Related Quality of Life Over Time in Children with Eosinophilic Esophagitis (EoE) and their Families.
- Eosinophilic Esophagitis: Clinical Presentation in Children.
- Resolution of acute IgE-mediated allergy with development of eosinophilic esophagitis triggered by the same Food.
- Immunotherapeutic approaches for the treatment of Eosinophilic esophagitis.
- Management of Difficult-to-Treat Atopic Dermatitis.
- Exposure to Food allergens through inflamed skin promotes intestinal Food allergy through the thymic stromal lymphopoietin-basophil axis.
- Omalizumab therapy is associated with reduced circulating basophil populations in Asthmatic children.
- Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.
- Basophils and allergic inflammation.
- Invariant Natural Killer T cells in children with Eosinophilic Esophagitis.
- Thymic stromal lymphopoietin-elicited basophil responses promote Eosinophilic esophagitis.
- PedsQL Eosinophilic esophagitis module: feasibility, reliability, and validity.
- Biphasic reactions in children undergoing oral Food challenges.
- Asthma and frequency of wheeze: risk factors for the persistence of atopic dermatitis in children.
- Relating microarray component testing and reported food allergy and food-triggered atopic Dermatitis: a real-world analysis.
- Natural history of cow's milk allergy.
- The natural history of Eosinophilic oesophagitis in the transition from childhood to adulthood.
- Esophageal epithelial and mesenchymal cross-talk leads to features of epithelial to mesenchymal transition in vitro.
- Identification of causative Foods in children with eosinophilic esophagitis treated with an elimination diet.
- Administration of influenza vaccine to pediatric patients with egg-induced anaphylaxis.
- Reslizumab in children and adolescents with Eosinophilic esophagitis: Results of a double-blind, randomized, placebo-controlled trial.
- TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation.
- Eosinophilic esophagitis: Updated consensus recommendations for children and adults.
- Invariant natural killer T cells from children with versus without Food allergy exhibit differential responsiveness to milk-derived sphingomyelin.
- Variation in prevalence, diagnostic criteria, and initial management options for Eosinophilic gastrointestinal diseases in the United States.
- Epidemiology of atopic Dermatitis and atopic march in children.
- From atopic dermatitis to Asthma: the atopic march.
- Common variants at 5q22 associate with pediatric Eosinophilic esophagitis.
- Variants of DENND1B associated with Asthma in children.
- A case-control study of sociodemographic and geographic characteristics of 335 children with Eosinophilic esophagitis.
- Food allergies and atopic Dermatitis: differentiating myth from reality.
- Association of Eosinophilic gastrointestinal disorders with other atopic disorders.
- 14 years of Eosinophilic esophagitis: clinical features and prognosis.
- Nutritional management of Eosinophilic esophagitis.
- Eosinophilic esophagitis in adults and children: evidence for a Food allergy component in many patients.
- Predictive values for skin prick test and atopy patch test for Eosinophilic esophagitis.
- Late diagnosis of tree nut and sesame allergy in patients previously sensitized but tolerant to peanut.
- Safety of topical calcineurin inhibitors in atopic Dermatitis: evaluation of the evidence.
- The black box warning for topical calcineurin inhibitors: looking outside the box.
- Authors' response to detection of causative Foods by skin prick and atopy patch tests in patients with eosinophilic esophagitis: things are not what they seem.
- Correlation of exhaled nitric oxide, spirometry and Asthma symptoms.
- Eosinophilic esophagitis: a 10-year experience in 381 children.
- Treatment of eosinophilic esophagitis with specific Food elimination diet directed by a combination of skin prick and patch tests.
- Atopic march: link to upper airways.
- Food allergy and additives: triggers in Asthma.
- The use of patch testing in the diagnosis of Food allergy.
- Effect of topical pimecrolimus on epicutaneous skin testing.
- Correlation of initial Food reactions to observed reactions on challenges.
- Atopic Dermatitis and the atopic march.
- Pollen and Eosinophilic esophagitis.
- Elemental diet is an effective treatment for Eosinophilic esophagitis in children and adolescents.
- Food allergy. Mechanisms, diagnosis, and management in children.
- The use of skin prick tests and patch tests to identify causative Foods in eosinophilic esophagitis.
- Filaggrin mutations and atopy: consequences for future therapeutics.
- Pimecrolimus cream in the management of patients with atopic eczema.
- Nonimmunoglobulin e-mediated immune reactions to Foods.
- Changing indications for upper endoscopy in children during a 20-year period.
- New genetic links in Eosinophilic esophagitis.
- The link between allergies and Eosinophilic esophagitis: implications for management strategies.
- Immunology and treatment of atopic Dermatitis.
- ORMDL3 variants associated with Asthma susceptibility in North Americans of European ancestry.
- 17q12-21 variants interact with smoke exposure as a risk factor for pediatric Asthma but are equally associated with early-onset versus late-onset Asthma in North Amer...
- Otolaryngologists may not be doing enough to diagnose pediatric Eosinophilic esophagitis.
- Food allergy: review, classification and diagnosis.
- Food Intolerance and childhood Asthma: what is the link?
- Addition of topical pimecrolimus to once-daily mid-potent steroid confers no short-term therapeutic benefit in the treatment of severe atopic Dermatitis; a randomized ...
- Atopy patch test for the diagnosis of Food protein-induced enterocolitis syndrome.
- Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Im...
- Eosinophilic oesophagitis and pollen.
- Eliminating Eosinophilic esophagitis.
- Report of the Topical Calcineurin Inhibitor Task Force of the American College of Allergy, Asthma and Immunology and the American Academy of Allergy, Asthma and Immuno...
- Immunomodulation and safety of topical calcineurin inhibitors for the treatment of atopic Dermatitis.
- Gene network analysis in a pediatric cohort identifies novel lung function genes.
- Food allergy presenting as a "septic"-appearing infant.
- Management of Food allergies.
- The Illness Management Survey: identifying adolescents' perceptions of barriers to adherence.
- NF-IL6, a member of the C/EBP family, regulates E1A-responsive promoters in the absence of E1A.
- Interleukin 6 enhances a cellular activity that functionally substitutes for E1A protein in transactivation.
- Epicutaneous sensitization with protein antigen induces localized allergic Dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized anti...
- Roles of TH1 and TH2 cytokines in a murine model of allergic Dermatitis.
- Resolution of childhood peanut allergy.
- An obligate role for T-cell receptor alphabeta+ T cells but not T-cell receptor gammadelta+ T cells, B cells, or CD40/CD40L interactions in a mouse model of atopic der...
- Anaphylaxis to raw potato.
- Natural history of peanut allergy.
- GWAS identifies four novel Eosinophilic esophagitis loci.
- Altered Esophageal Histamine Receptor Expression in Eosinophilic Esophagitis (EoE): Implications on Disease Pathogenesis.
- Food Protein-induced Enterocolitis Syndrome: Insights from Review of a Large Referral Population.
- The management of Eosinophilic esophagitis.
Schools
Mount Sinai School of Medicine
Yale New Haven Hospital
Chldns Hospital
Conditions Treated
- Asthma
- Dermatitis Due to Food
- Dermatitis Due to Substances Taken Internally
- Eosinophilic Esophagitis
Doctors Specialties
- Pediatrics
- Allergy
- Immunology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Local Value Network EPO
- Local Value Network HMO
- Local Value Network HMO+
- Local Value Network POS+
- Local Value Network PPO
- Personal Choice PPO
- Regional Pref Network EPO
- Regional Pref Network HMO
- Regional Pref Network HMO+
- Regional Pref Network POS+
- Regional Pref Network PPO
- Blue Card PPO
- Capital Blue Cross
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- Open Access Plus
- Commercial Insurance Company
- CoreSource
- Coventry Health America PPO
- Coventry Health Care of Delaware PPO
- Emblem Health
- GHI PPO
- Health Insurance Plan of Greater New York (HIP) PPO
- Fidelis Care HMO
- First Health (Coventry Health Care) PPO
- Geisinger Health Plan
- HealthPartners
- Community Blue PPO
- Advance EPO
- Direct Access
- Horizon Blue Cross Blue Shield HMO
- Horizon Blue Cross Blue Shield POS
- Horizon Blue Cross Blue Shield PPO
- Choice Care PPO
- Keystone Health Plan East HMO
- Medicare MCR
- MultiPlan PPO
- Freedom Plan
- PHP-Physicians Health Plan
- QualCare HMO
- QualCare PPO
- Tricare
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- Oxford Liberty
- United Healthcare
Awards
- Fellow (FAAAAI)
- Philadelphia Magazine
- America's Top Doctors
- Top Doctor
- Top Doc
- Top Docs
- Marquis “Who’s Who in Americaâ€Â
- American Academy of Pediatrics
- Marquis Who’s Who in Medicine and Healthcare 2004-07
- Top Physicians in America
- Fellow in American Academy of Allergy Asthma and Immunology
- Pennsylvania Allergy Education and Research Trust Award
- Ethel Brown Foerderer Award for Excellence
- Glaxo Wellcome Allergy Training Award
- Charles A. Janeway Scholarship
- Distinguished Accomplishment in the NIH Biomedical Sciences Research Award for Clinical Trainees Program
- Sigma Xi
- Magna cum laude in chemistry
- Castle Connolly’s America’s Top Doctor
- Stanley Weil Fellowship
- Super Doctor
- NIH Medical Scientist Training Program
Education
-
Boston Children's Hospital -
Yale New Haven Children's Center -
Icahn School of Medicine at Mount Sinai
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