Attending Physician/Hospitalist
Internal Medicine
Dr. Laine J. Murphey, MD
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Laine Murphey practices Internal Medicine. He went to medical school at Oregon Health & Science University School of Medicine. Doctor Laine J. Murphey, MD is also published. He has 38 publications published. The lastest publication: "Effects of morphine and cocaine on breathing control in neonatal animals: a minireview.'
Publications
- Urinary free cortisol: an intermediate phenotype and a potential genetic marker for a salt-resistant subset of essential hypertension.
- Bradykinin B(2) receptor does not contribute to blood pressure lowering during AT(1) receptor blockade.
- Urinary prostaglandin F2alpha is generated from the isoprostane pathway and not the cyclooxygenase in humans.
- Angiotensin II induces interleukin-6 in humans through a mineralocorticoid receptor-dependent mechanism.
- Bradykinin and its metabolite bradykinin 1-5 inhibit thrombin-induced platelet aggregation in humans.
- Bradykinin B2 receptor knockout mice are protected from thrombosis by increased nitric oxide and prostacyclin.
- Angiotensin-converting enzyme inhibition increases basal vascular tissue plasminogen activator release in women but not in men.
- A pilot study indicating that bradykinin B2 receptor antagonism attenuates protamine-related hypotension after cardiopulmonary bypass.
- Quantification of the major urinary metabolite of PGE2 by a liquid chromatographic/mass spectrometric assay: determination of cyclooxygenase-specific PGE2 synthesis in...
- The preparation and characterization of novel peptide antagonists to thrombin and factor VIIa and activation of protease-activated receptor 1.
- Uric acid and the state of the intrarenal renin-angiotensin system in humans.
- Angiotensin-converting enzyme inhibition and smoking potentiate the kinin response to cardiopulmonary bypass.
- Thyroid function and blood pressure homeostasis in euthyroid subjects.
- Loss of sodium modulation of plasma kinins in human hypertension.
- Angiotensin-converting enzyme inhibition alters the fibrinolytic response to cardiopulmonary bypass.
- Acute angiotensin II increases plasma F2-isoprostanes in salt-replete human hypertensives.
- Effect of combined AT1 receptor and aldosterone receptor antagonism on plasminogen activator inhibitor-1.
- Formation of highly reactive A-ring and J-ring isoprostane-like compounds (A4/J4-neuroprostanes) in vivo from docosahexaenoic acid.
- Ethnicity affects vasodilation, but not endothelial tissue plasminogen activator release, in response to bradykinin.
- Dipeptidyl peptidase IV activity in patients with ACE-inhibitor-associated angioedema.
- Interactive effect of PAI-1 4G/5G genotype and salt intake on PAI-1 antigen.
- Quantification of BK1-5, the stable bradykinin plasma metabolite in humans, by a highly accurate liquid-chromatographic tandem mass spectrometric assay.
- Angiotensin-(1-7) does not affect vasodilator or TPA responses to bradykinin in human forearm.
- Bradykinin stimulates tissue plasminogen activator release from human forearm vasculature through B(2) receptor-dependent, NO synthase-independent, and cyclooxygenase-...
- Endogenous bradykinin and the renin and pressor responses to furosemide in humans.
- Angiotensin-converting enzyme insertion/deletion polymorphism modulates the human in vivo metabolism of bradykinin.
- Metabolism of bradykinin In vivo in humans: identification of BK1-5 as a stable plasma peptide metabolite.
- Effects of morphine and cocaine on breathing control in neonatal animals: a minireview.
- Quantitation of benzoylnorecgonine and other cocaine metabolites in meconium by high-performance liquid chromatography.
- Morphine-6-beta-D-glucuronide respiratory pharmacodynamics in the neonatal guinea pig.
- In vitro hepatic biotransformation of cocaine in maternal and fetal guinea pigs. Induction of cocaine N-demethylation with cocaine pretreatment.
- Diffusion of morphine-6-beta-D-glucuronide into the neonatal guinea pig brain during drug-induced respiratory depression.
- Cocaine metabolites in the neonate: potential for toxicity.
- Developmental change of mu opioid receptors in neonatal guinea pig brain stem.
- Pharmacokinetics and metabolism of cocaine in maternal and fetal guinea pigs.
- Human colorectal cancer cells efficiently conjugate the cyclopentenone prostaglandin, prostaglandin J(2), to glutathione.
- A single dose, three-arm, placebo-controlled, phase I study of the bradykinin B2 receptor antagonist Anatibant (LF16-0687Ms) in patients with severe traumatic brain in...
Schools
Oregon Health Sciences University
Vanderbilt University Med Center
Doctors Specialties
- Internal Medicine
Accepted Insurances
Education
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Vanderbilt University -
Oregon Health & Science University School of Medicine
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1710957469 |
| Last Name Of The Provider | MURPHEY |
| First Name Of The Provider | LAINE |
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