Professor Emeritus of Medicine, University Illinois at Chicago
Endocrinology
Dr. Lawrence A. Frohman, MD
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Lawrence Frohman is an expert in the field of Endocrinology. He attended University of Michigan Medical School. He has 3 awards "Regional Top Doctor", "Fellow (FACP)" and "Elected Member". Lawrence A. Frohman, MD is a published doctor and has 100 publications published. The lastest was: 'Hyperglycemia and hyperglucagonemia following neurotensin administration.'
Publications
- Efficacy and Safety of an Octreotide Implant in the Treatment of Patients with Acromegaly.
- Clinical, genetic and molecular characterization of patients with familial isolated pituitary adenomas (FIPA).
- Use of the metallothionein promoter-human growth hormone-releasing hormone (GHRH) mouse to identify regulatory pathways that suppress pituitary somatotrope hyperplasia...
- The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas.
- Normal physiology of hypothalamic pituitary regulation.
- Pituitary tumor enlargement in two patients with acromegaly during pegvisomant therapy.
- Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse.
- Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog.
- Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults.
- Tumor deletion mapping on chromosome 11q13 in eight families with isolated familial somatotropinoma and in 15 sporadic somatotropinomas.
- p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow.
- Isolated familial somatotropinoma.
- Isolated familial somatotropinomas: clinical and genetic considerations.
- Who needs growth hormone therapy? Growth hormone helps some, but its use as an "anti-aging" agent is dubious.
- Growth hormone-releasing hormone and pituitary development, hyperplasia and tumorigenesis.
- Controversy about treatment of growth hormone-deficient adults: a commentary.
- Two distinct insulin-related molecules in the guinea pig: immunological and biochemical characterization of insulin-like immunoactivity from extrapancreatic tissues of...
- Hyperphagia and obesity following ventromedial hypothalamic lesions in rats with subdiaphragmatic vagotomy.
- Hyperinsulinemia in tube-fed hypophysectomized rats bearing hypothalamic lesions.
- Effects of hypothalamic lesions at different loci on development of hyperinsulinemia and obesity in the weanling rat.
- Metabolism of intravenously injected 14 C-glucose in weanling rats with hypothalamic obesity.
- Gonadal function in women with chronic renal failure: a study of the hypothalamo-pituitary-ovarian axis.
- Concomitant association between high plasma levels of growth hormone and low hepatic mixed-function oxidase activity in the young rat.
- Radio-frequency vs. electrolytic VMH lesions: differential effects on plasma hormones.
- Effect of hypothalamic stimulation on plasma glucose, insulin, and glucagon levels.
- Food intake in hypothalamic obesity.
- Central glucoprivation: some physiological effects induced by the intraventricular administration of 2-deoxy-d-glucose.
- Plasma insulin and triglyceride levels after hypothalamic lesions in weanling rats.
- VMH obesity reduced but not reversed by scopolamine methyl nitrate.
- Hypothalamic obesity: comparison of radio-frequency and electrolytic lesions in weanling rats.
- Postabsorptive hyperinsulinemia in rats with subdiaphragmatic vagotomy.
- Hypothalamic obesity in female rats in absence of vagally mediated hyperinsulinemia.
- Aspirin reduces the incidence of second eye NAION: a retrospective study.
- Cortisol induction of growth hormone synthesis in a clonal line of rat pituitary tumor cells in culture.
- Clinical characteristics, diagnostic criteria and therapeutic outcomes in autoimmune optic neuropathy.
- Somatostatin secretion and action in the regulation of growth hormone secretion.
- Growth hormone: independent release of big and small forms from rat pituitary in vitro.
- Effect of vagotomy and vagal stimulation on insulin secretion.
- Effect of caloric restriction on the glucose tolerance and plasma insulin of the sand rat.
- The effect of lateral hypothalamic lesions in weanling rats bearing lesions in the ventromedial hypothalamic nuclei.
- Insulin responsiveness in vitro of diaphragm and adipose tissue from weanling rats with hypothalamic obesity.
- Studies of insulin sensitivity in vivo in weanling rats with hypothalamic obesity.
- Clinical neuropharmacology of hypothalamic releasing factors.
- Effect of dorsomedial hypothalamic lesions before and after placement of obesity-producing ventromedial hypothalamic lesions in the weanling male rat.
- Effects of glucocorticoid administration to rats on in vitro intermediary metabolism.
- Glucose and fatty acid utilization by tissues of weanling rats with ventromedial hypothalamic lesions.
- Nonirritative lesions of VMH: effects on plasma insulin, obesity, and hyperreactivity.
- Plasma growth hormone responses and growth retardation of hypothyroidism.
- Loss of central nervous system component of dopaminergic inhibition of prolactin secretion in patients with prolactin-secreting pituitary tumors.
- A neuroendocrine study of supersensitivity in tardive dyskinesia.
- Immunoreactive neurotensin in the pancreas of genetically obese and diabetic mice. A longitudinal study.
- Diurnal variation in release of somatostatin-like immunoreactivity from incubated, rat hypothalamus and cerebral cortex.
- Somatostatin-like immunoactivity and biological activity is present in Tetrahymena pyriformis, a ciliated protozoan.
- Multiphasic effect of porcine stalk-median eminence extract on growth hormone release from perifused rat pituitaries.
- Immunologic and biologic properties of antibodies to a glucagon-serum albumin polymer.
- Hypothalamic stimulation of growth hormone secretion.
- Stimulation of insulin secretion in rats by pargyline and mebanazine.
- Delayed TSH release in anorexia nervosa following injection of thyrotropin-releasing hormone (TRH).
- Evidence for possible precursors in the synthesis of growth hormone by rat and human fetal anterior pituitary in vitro.
- Production of transgenic sheep with growth-regulating genes.
- Hyperglycemia and hyperglucagonemia following neurotensin administration.
- Hypertriglyceridemia in weanling rats with hypothalamic obesity.
- The hypothalamus and metabolic control.
- Factors modifying plasma insulin and glucose responses to ventromedial hypothalamic stimulation.
- Inhibitory feedback effects of prolactin on its secretion involve central nervous system dopaminergic mediation.
- Effect of the dopa decarboxylase inhibitor MK-486 on L-dopa-induced inhibition of prolactin secretion: evidence for CNS participation in the L-dopa effects.
- Solution structures of cyclic and dicyclic analogues of growth hormone releasing factor as determined by two-dimensional NMR and CD spectroscopies and constrained mole...
- A RADIOIMMUNOLOGICAL ASSAY METHOD FOR INSULIN USING INSULIN-125I AND GEL FILTRATION.
- Evidence for lactotroph dopamine resistance in idiopathic hyperprolactinemia.
- Ovarian function in chronic renal failure: evidence suggesting hypothalamic anovulation.
- Metabolic clearance and secretion rates of human prolactin in normal subjects and in patients with chronic renal failure.
- Continuing occurrence of thyroid nodules after head and neck irradiation. Relation to plasma thyroglobulin concentration.
- Scintigraphic thyroid abnormalities after radiation. A controlled study with 99mTc pertechnetate scanning.
- Hypothalamic dysfunction associated with hemochromatosis.
- Salivary gland neoplasms as a late consequence of head and neck irradiation.
- Plasma thyroglobulin in detecting thyroid carcinoma after childhood head and neck irradiation.
- TRH immunoreactivity in human urine: evidence for dissociation from TRH.
- Neuropharmacologic control of neuroendocrine function in man.
- Diseases of hypothalamic releasing factors.
- Diethylstilbestrol inhibits tumor growth and prolactin production in rat pituitary tumors.
- A new familial syndrome characterized by pigmentary retinopathy, hypogonadism, mental retardation, nerve deafness and glucose intolerance.
- Six-month follow-up in weanling rats with ventromedial and dorsomedial hypothalamic lesions: somatic, endocrine, and metabolic changes.
- CNS peptides and glucoregulation.
- Temporal relationship of tissue somatostatin-like immunoreactivity to metabolic changes in genetically obese and diabetic mice.
- The role of neurotensin in the regulation of carbohydrate metabolism and in diabetes.
- Diagnosis and treatment of acromegaly complications.
- A neuroendocrine overview of aging.
- Dissociation of prolactin-releasing activity from thyrotropin-releasing hormone in porcine stalk median eminence.
- Differential effects of neonatal and adult androgen exposure on the growth hormone secretory pattern in male rats.
- Relationship of growth hormone to the growth retardation associated with maternal dietary restriction.
- The diurnal variation of immunoreactive thyrotropin-releasing hormone and somatostatin in the cerebrospinal fluid of the rhesus monkey.
- Release of somatostatin and thyrotropin-releasing hormone from rat hypothalamic fragments in vitro.
- Heterogeneity of purified human pituitary luteinizing hormone: effect on hormone measurement by radioimmunoassay.
- Effect of passive immunization with an antiserum to thyrotropin (TSH)-releasing hormone on plasma TSH levels in thyroidectomized rats.
- Characterization of growth hormone of different molecular weights in rat, dog and human pituitaries.
- Growth hormone releasing action of a Pseudomonas endotoxin (piromen).
- Effects of ventromedial hypothalamic destruction in rats with preexisting streptozotocin-induced diabetes.
- Prolactin-suppressive effects of two aminotetralin analogs of dopamine: their use in the characterization of the pituitary dopamine receptor.
- Acute effects of alloxan- and streptozotocin-induced insulin deficiency on somatostatin and glucagon secretion by the perfused isolated rat pancreatico-duodenal prepar...
Schools
University Of Michigan Medical School
Grace New Haven Community Hospital
Duke University Med Center
Doctors Specialties
- Internal Medicine
- Endocrinology
Accepted Insurances
Awards
- Regional Top Doctor
- Fellow (FACP)
- Elected Member
Education
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University of Michigan Medical School
Hospital
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University of Illinois Hospital & Health Sciences System -
Northwestern Memorial Hospital -
Jesse Brown Veterans Affairs Medical Center
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