Professor and Chairman Department of Pathology and Anatomical Sciences University of Missouri
Pathology
Dr. Lester J. Layfield, MD
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Lester J. Layfield, MD works in the field of Pathology. He researched medicine at David Geffen School of Medicine at UCLA. David Geffen School of Medicine at UCLA is one of the top medical schools in the US. David Geffen School of Medicine at UCLA is ranked 13/7 in Research/PrimaryCare. Lester Layfield is a published doctor. He published 99 publications, including: 'Cytologic separation of branchial cleft cyst from metastatic cystic squamous cell carcinoma: A multivariate analysis of nineteen cytomorphologic features.'
Publications
- Cytologic separation of branchial cleft cyst from metastatic cystic squamous cell carcinoma: A multivariate analysis of nineteen cytomorphologic features.
- Interobserver reproducibility for HER2/neu immunohistochemistry: A comparison of reproducibility for the HercepTest™ and the 4B5 antibody clone.
- Can imaging criteria distinguish enchondroma from grade 1 chondrosarcoma?
- Malignancy risk for the categories: Non-diagnostic, benign, atypical, suspicious, and malignant used in the categorization of endobronchial ultrasound guided-fine need...
- Axillary lymph node FNA in women with breast cancer is a highly accurate procedure, so why are core biopsies being done?
- Cancer tracking: clinician compliance and program outcome.
- Guidelines for pancreaticobiliary cytology from the Papanicolaou Society of Cytopathology: A review.
- Cervical neuroendocrine tumor in a young female with Lynch Syndrome.
- Standardized terminology and nomenclature for pancreatobiliary cytology: The Papanicolaou Society of Cytopathology guidelines.
- Utilization of ancillary studies in the cytologic diagnosis of biliary and pancreatic lesions: The papanicolaou society of cytopathology guidelines for pancreatobiliar...
- Increased Melanoma Risk in Individuals With Papillary Thyroid Carcinoma.
- Diagnostic accuracy and clinical utility of biopsy in musculoskeletal lesions: A comparison of fine-needle aspiration, core, and open biopsy techniques.
- Clinical evaluation, imaging studies, indications for cytologic study, and preprocedural requirements for duct brushing studies and pancreatic FNA: The papanicolaou so...
- Cytotechnologist screening of fine-needle aspiration specimens: Impact on turnaround time and diagnostic accuracy.
- Significance of the diagnostic categories "atypical" and "suspicious for malignancy" in the cytologic diagnosis of solid pancreatic masses.
- Critical values: Has their time arrived for cytopathology?
- Malignancy risk associated with diagnostic categories defined by the Papanicolaou Society of Cytopathology pancreaticobiliary guidelines.
- Juvenile Granulosa Cell Tumors: Immunoreactivity for CD99 and Fli-1 and EWSR1 Translocation Status: A Study of 11 Cases.
- Histologic, Serologic, and Tribologic Findings in Failed Metal-on-Metal Total Hip Arthroplasty: AAOS Exhibit Selection.
- Fine-Needle Aspiration Cytology for the Diagnosis of Metastatic Melanoma: Systematic Review and Meta-Analysis.
- Significance of atypia in pancreatic and bile duct brushings: Follow-Up analysis of the categories atypical and suspicious for malignancy.
- Identification of factors predictive of malignancy in patients with atypical biliary brushing results obtained via ERCP.
- Rapid On-Site Evaluation Reduces Needle Passes in Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Solid Pancreatic Lesions: A Risk-Benefit Analysis.
- Quality appraisal of diagnostic accuracy studies in fine-needle aspiration cytology: a survey of risk of bias and comparability.
- A comparative needle study: EUS-FNA procedures using the HD ProCore(™) and EchoTip(®) 22-gauge needle types.
- Risk-benefit analysis of sampling methods for fine-needle aspiration cytology: a mathematical modeling approach.
- The influence of rapid onsite evaluation on the adequacy rate of fine-needle aspiration cytology: a systematic review and meta-analysis.
- Solitary peripheral pulmonary papilloma evaluation on frozen section: A potential pitfall for the pathologist.
- Characterization of synovial sarcoma calcification.
- The comparative effectiveness of fine-needle aspiration cytology sampling policies: a simulation study.
- Gonadotroph Adenoma with Secondary Hypersecretion of Testosterone.
- Gastrointestinal Stromal Tumors: Clinical Significance of p53 Expression, MDM2 Amplification, and KIT Mutation Status.
- Rapid On-Site Evaluation Increases Endoscopic Ultrasound-Guided Fine-Needle Aspiration Adequacy for Pancreatic Lesions.
- Negative loop electrosurgical cone biopsy finding following a biopsy diagnosis of high-grade squamous intraepithelial lesion: frequency and clinical significance.
- Clinician compliance with laboratory regulations requiring submission of relevant clinical data: A one year retrospective analysis.
- Intraprocedural evaluation of fine-needle aspiration smears: How good are we?
- Atypical Intradermal Smooth Muscle Neoplasms (Formerly Cutaneous Leiomyosarcomas): Case Series, Immunohistochemical Profile and Review of the Literature.
- Respiratory cytology in the era of molecular diagnostics: a review.
- Bridging the gap: cytopathology at the threshold of personalized medicine.
- Diagnosis of gastrointestinal stromal tumors from minute specimens: cytomorphology, immunohistochemistry, and molecular diagnostic findings.
- Cytomorphologic diagnosis and HPV testing of metastatic and primary oropharyngeal squamous cell carcinomas: a review and summary of the literature.
- HER2/neu Gene Amplification Heterogeneity: The Significance of Cells With a 3: 1 HER2/CEP17 Ratio.
- Classification, molecular characterization, and the significance of pten alteration in leiomyosarcoma.
- Methods specification for diagnostic test accuracy studies in fine-needle aspiration cytology: a survey of reporting practice.
- MDM2 Amplification in Malignant Peripheral Nerve Sheath Tumors Correlates With p53 Protein Expression.
- Extraneous tissue: a potential source for diagnostic error in surgical pathology.
- A Systematic Review and Meta-analysis of the Diagnostic Accuracy of Frozen Section for Parotid Gland Lesions.
- A Systematic Review and Meta-analysis of the Diagnostic Accuracy of Ultrasound-Guided Core Needle Biopsy for Salivary Gland Lesions.
- Yolk Sac Tumor of the Thyroid Gland: A Case Report.
- A systematic review and meta-analysis of the diagnostic accuracy of fine-needle aspiration cytology for parotid gland lesions.
- Fine-needle aspiration diagnosis of an intraosseous amyloidoma.
- Inflammatory myxohyaline tumor of distal extremities:Cytologic findings in a lesion simulating a high-grade myxoid sarcoma.
- KIT mutations in ocular melanoma: frequency and anatomic distribution.
- Utilization of Unlabeled Probes for the Detection of Fibroblast Growth Factor Receptor 2 Exons 7 and 12 Mutations in Endometrial Carcinoma.
- C-KIT and PDGFRA zygosity in gastrointestinal stromal tumors: Correlation with tumor site, tumor size, exon, and CD117 immunohistochemistry.
- Metastatic disease to the pancreas documented by endoscopic ultrasound guided fine-needle aspiration: A seven-year experience.
- Metastatic pancreatic adenocarcinoma presenting as a large pelvic mass mimicking primary osteogenic sarcoma: a series of two patient cases.
- Specimen labeling errors in surgical pathology: an 18-month experience.
- Fibromatosislike metaplastic carcinoma of the breast as a diagnostic pitfall for fine needle aspiration cytology: a case report.
- Cytologic features of pancreatic intraepithelial neoplasia and pancreatitis: Potential pitfalls in the diagnosis of pancreatic ductal carcinoma.
- Follicular variant of papillary carcinoma: reproducibility of histologic diagnosis and utility of HBME-1 immunohistochemistry and BRAF mutational analysis as diagnosti...
- Fine-needle aspiration of primary osseous lesions: A cost effectiveness study.
- Cytopathology of the pancreas: neoplastic and nonneoplastic entities.
- Chondroid syringoma: case report of a highly unusual foot tumor.
- Initial margin status for invasive ductal carcinoma of the breast and subsequent identification of carcinoma in reexcision specimens.
- Implications of the proposed thyroid fine-needle aspiration category of "follicular lesion of undetermined significance": A five-year multi-institutional analysis.
- Cytologic diagnosis of osseous lesions: a review with emphasis on the diagnosis of primary neoplasms of bone.
- Lack of BRAF activating mutations in prostate adenocarcinoma: a study of 93 cases.
- Thyroid aspiration cytology: current status.
- Histologic, immunohistochemical, and molecular classification of 52 IPMNs of the pancreas.
- A gastrointestinal stromal tumor of the stomach morphologically resembling a neurofibroma: demonstration of a novel platelet-derived growth factor receptor alpha exon ...
- Monoplex LightCycler polymerase chain reaction quantitation of the HER2 gene for quality assurance of HER2/neu testing by immunohistochemistry and fluorescence in situ...
- Tyrosine kinase activating mutations in human malignancies: implications for diagnostic pathology.
- The use of EGFR exon 19 and 21 unlabeled DNA probes to screen for activating mutations in non-small cell lung cancer.
- Post-thyroid FNA testing and treatment options: a synopsis of the National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference.
- Translocations and amplifications of chromosome 12 in liposarcoma demonstrated by the LSI CHOP breakapart rearrangement probe.
- Giant-cell containing neoplasms of the pancreas: an aspiration cytology study.
- Cytologic fine needle aspiration findings by vegetant intravascular hemangioendothelioma.
- Fine-needle aspiration in the diagnosis of head and neck lesions: a review and discussion of problems in differential diagnosis.
- High-resolution melting amplicon analysis as a method to detect c-kit and platelet-derived growth factor receptor alpha activating mutations in gastrointestinal stroma...
- In situ and invasive components of mammary adenocarcinoma: comparison of Her-2/neu status.
- Molecular diagnostic testing as an adjunct to morphologic evaluation of pancreatic ductal system brushings: potential augmentation for diagnostic sensitivity.
- Effects of fixative and fixation protocols on assessment of Her-2/neu oncogene amplification status by fluorescence in situ hybridization.
- Cost efficiency analysis for fine-needle aspiration in the workup of parotid and submandibular gland nodules.
- Detection of c-kit exons 11- and 17-activating mutations in testicular seminomas by high-resolution melting amplicon analysis.
- Detection of epidermal growth factor receptor and human epidermal growth factor receptor 2 activating mutations in lung adenocarcinoma by high-resolution melting ampli...
- Detection of EGFR- and HER2-activating mutations in squamous cell carcinoma involving the head and neck.
- BRAF and c-kit gene copy number in mutation-positive malignant melanoma.
- Evaluation of Her-2/neu gene status in osteosarcoma by fluorescence in situ hybridization and multiplex and monoplex polymerase chain reactions.
- A c-kit-negative gastrointestinal stromal tumor with a platelet-derived growth factor receptor alpha mutation.
- Epidermal growth factor receptor gene amplification and protein expression in glioblastoma multiforme: prognostic significance and relationship to other prognostic fac...
- Interobserver agreement and reproducibility in classification of invasive breast carcinoma: an NCI breast cancer family registry study.
- A comparison of immunohistochemical stain quality in conventional and rapid microwave processed tissues.
- Quest for a uniform cyto-diagnostic approach to thyroid aspirates: a consensus proposal.
- Correlation of HER2 gene amplification with immunohistochemistry in breast cancer as determined by a novel monoplex polymerase chain reaction assay.
- HPV DNA testing in the triage of atypical squamous cells of undetermined significance (ASCUS): cost comparison of two methods.
- c-KIT mutation analysis for diagnosis of gastrointestinal stromal tumors in fine needle aspiration specimens.
- Human malignant melanoma: detection of BRAF- and c-kit-activating mutations by high-resolution amplicon melting analysis.
Schools
David Geffen School Of Medicine At UCLA University Of California Los Angeles
University Washington
University Of California Los Angeles
Doctors Specialties
- Cytopathology
- Pathology
Accepted Insurances
Education
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UCLA Medical Center -
University of Washington -
David Geffen School of Medicine at UCLA
Hospital
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Duke University Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1033209648 |
| Last Name Of The Provider | LAYFIELD |
| First Name Of The Provider | LESTER |
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