Medical Director, Oncology Drug Development Abbvie Biotherapeutics
Pediatric Hematology & Oncology
Dr. Louie Naumovski, MD
Louie Naumovski practices Pediatric Hematology & Oncology. He studied medicine at Stanford University School of Medicine. Stanford University School of Medicine is a top medical college. Stanford University School of Medicine is ranked 2/25 in Research/PrimaryCare. Louie Naumovski is a published doctor and has 68 publications published. The lastest was: 'Endothelial cell apoptosis in capillary network remodeling.'
Publications
- Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification.
- Glembatumumab vedotin, a conjugate of an anti-glycoprotein non-metastatic melanoma protein B mAb and monomethyl auristatin E for the treatment of melanoma and breast c...
- Effects of motexafin gadolinium in a phase II trial in refractory chronic lymphocytic leukemia.
- The novel expanded porphyrin, motexafin gadolinium, combined with [90Y]ibritumomab tiuxetan for relapsed/refractory non-Hodgkin's lymphoma: preclinical findings and re...
- Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds.
- Synthesis and biologic properties of hydrophilic sapphyrins, a new class of tumor-selective inhibitors of gene expression.
- Tumor localization and antitumor efficacy of novel sapphyrin compounds.
- Motexafin gadolinium-induced cell death correlates with heme oxygenase-1 expression and inhibition of P450 reductase-dependent activities.
- Motexafin gadolinium modulates levels of phosphorylated Akt and synergizes with inhibitors of Akt phosphorylation.
- New polyethyleneglycol-functionalized texaphyrins: synthesis and in vitro biological studies.
- Motexafin gadolinium and zinc induce oxidative stress responses and apoptosis in B-cell lymphoma lines.
- A practical guideline for calculating parenteral nutrition cycles.
- Motexafin gadolinium induces mitochondrially-mediated caspase-dependent apoptosis.
- Control of ASPP2/(53BP2L) protein levels by proteasomal degradation modulates p53 apoptotic function.
- Sapphyrins induce apoptosis in hematopoietic tumor-derived cell lines and show in vivo antitumor activity.
- ARMER, apoptotic regulator in the membrane of the endoplasmic reticulum, a novel inhibitor of apoptosis.
- ASPP2 inhibits APP-BP1-mediated NEDD8 conjugation to cullin-1 and decreases APP-BP1-induced cell proliferation and neuronal apoptosis.
- Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding sites.
- Inhibition of cell death by ribosomal protein L35a.
- Intracellular redistribution of interferon-inducible proteins Nmi and IFP 35 in apoptotic cells.
- ASPP proteins specifically stimulate the apoptotic function of p53.
- Two-hybrid interactions confirmed by coimmunoprecipitation of epitope-tagged clones.
- p53-interacting protein 53BP2 inhibits clonogenic survival and sensitizes cells to doxorubicin but not paclitaxel-induced apoptosis.
- Imaging cyclophosphamide-induced intramedullary apoptosis in rats using 99mTc-radiolabeled annexin V.
- Proapoptotic p53-interacting protein 53BP2 is induced by UV irradiation but suppressed by p53.
- Interferon-inducible Myc/STAT-interacting protein Nmi associates with IFP 35 into a high molecular mass complex and inhibits proteasome-mediated degradation of IFP 35.
- Interferon-alpha induces nmi-IFP35 heterodimeric complex formation that is affected by the phosphorylation of IFP35.
- Subcellular localization of interferon-inducible Myc/stat-interacting protein Nmi is regulated by a novel IFP 35 homologous domain.
- Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic mice.
- Vascular cell apoptosis: cell type-specific modulation by transforming growth factor-beta1 in endothelial cells versus smooth muscle cells.
- Endothelial cell apoptosis in capillary network remodeling.
- Imaging of apoptosis (programmed cell death) with 99mTc annexin V.
- Interferon-induced upregulation and cytoplasmic localization of Myc-interacting protein Nmi.
- In vivo detection and imaging of phosphatidylserine expression during programmed cell death.
- BCL-2 expression does not not correlate with patient outcome in pediatric acute myelogenous leukemia.
- Method to screen for relevant yeast two-hybrid-derived clones by coimmunoprecipitation and colocalization of epitope-tagged fragments--application to Bcl-xL.
- Quantitative analysis of apoptotic cell death using proton nuclear magnetic resonance spectroscopy.
- Nucleotide excision repair capacity is attenuated in human promyelocytic HL60 cells that overexpress BCL2.
- The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M.
- The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties.
- Detection of apoptotic cell death by proton nuclear magnetic resonance spectroscopy.
- Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells.
- Bcl2 inhibits apoptosis associated with terminal differentiation of HL-60 myeloid leukemia cells.
- Appendix: a model of plaque formation.
- Chromogenic detection of antigen in bacteriophage plaques: a microplaque method applicable to large-scale screening.
- Molecular cloning of eucaryotic genes required for excision repair of UV-irradiated DNA: isolation and partial characterization of the RAD3 gene of Saccharomyces cerev...
- Use of plasmid-mediated resistance to the antibiotic G418 for the rapid screening of a yeast mutant library.
- Saccharomyces cerevisiae RAD2 gene: isolation, subcloning, and partial characterization.
- A DNA repair gene required for the incision of damaged DNA is essential for viability in Saccharomyces cerevisiae.
- Construction of plasmid vectors that facilitate subcloning and recovery of yeast and Escherichia coli DNA fragments.
- Physical mapping and complete nucleotide sequence of the denV gene of bacteriophage T4.
- RAD3 gene of Saccharomyces cerevisiae: nucleotide sequence of wild-type and mutant alleles, transcript mapping, and aspects of gene regulation.
- Molecular approaches to the study of nucleotide excision repair in eukaryotes.
- Partial complementation of the UV sensitivity of E. coli and yeast excision repair mutants by the cloned denV gene of bacteriophage T4.
- The RAD3 gene of Saccharomyces cerevisiae: isolation and characterization of a temperature-sensitive mutant in the essential function and of extragenic suppressors of ...
- Philadelphia chromosome-positive acute lymphoblastic leukemia cell lines without classical breakpoint cluster region rearrangement.
- Nucleotide excision repair genes from the yeast Saccharomyces cerevisiae.
- Analysis of the essential and excision repair functions of the RAD3 gene of Saccharomyces cerevisiae by mutagenesis.
- A new DNA-dependent ATPase which stimulates yeast DNA polymerase I and has DNA-unwinding activity.
- Partial suppression of an ochre mutation in Saccharomyces cerevisiae by multicopy plasmids containing a normal yeast tRNAGln gene.
- Rad3 protein of Saccharomyces cerevisiae: overexpression and preliminary characterization using specific antibodies.
- Purification and characterization of Rad3 ATPase/DNA helicase from Saccharomyces cerevisiae.
- SUP-HD1: a new Hodgkin's disease-derived cell line with lymphoid features produces interferon-gamma.
- Current therapy for chronic granulomatous disease.
- Ingestion of a laryngoscope light bulb during delivery room resuscitation.
- Treatment of thrombotic thrombocytopenic purpura with cryosupernatant.
- Outbreak of ceftazidime resistance due to a novel extended-spectrum beta-lactamase in isolates from cancer patients.
Schools
Stanford University
Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Education
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Stanford University School of Medicine