Physician
Pathology
Dr. Megan S. Lim, MD
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Megan S. Lim is an expert in the field of Pathology. Dr. Megan S. Lim is a published physician. He has 102 publications published. The most current publication "Pathological findings in human autoimmune lymphoproliferative syndrome."
Publications
- Differential proteomic analysis of endemic and sporadic Epstein-Barr virus-positive and negative Burkitt Lymphoma.
- Evaluation of Allele-Specific PCR and Immunohistochemistry for the Detection of BRAF V600E Mutations in Hairy Cell Leukemia.
- A novel recurrent NPM1-TYK2 gene fusion in cutaneous CD30-positive lymphoproliferative Disorders.
- Fbxo45 Inhibits Calcium-Sensitive Proteolysis of N-cadherin and Promotes Neuronal Differentiation*
- Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer Cell survival.
- Activating FGFR2-RAS-BRAF Mutations in Ameloblastoma.
- High prevalence of somatic MAP2K1 mutations in BRAF V600E negative Langerhans Cell histiocytosis.
- Integrated genomic sequencing reveals mutational landscape of T-cell prolymphocytic Leukemia.
- Global Phosphoproteomic Profiling Reveals Distinct Signatures in B-Cell Non-Hodgkin Lymphomas.
- GATA-3 expression identifies a high-risk subset of PTCL, NOS with distinct molecular and clinical features.
- Requisite Analytic and Diagnostic Performance Characteristics for the Clinical Detection of BRAF V600E in Hairy Cell Leukemia: A Comparison of 2 Allele-specific PCR As...
- Oncogenic Y641 mutations in EZH2 prevent Jak2/β-TrCP-mediated degradation.
- Laboratory practice guidelines for detecting and reporting JAK2 and MPL mutations in Myeloproliferative neoplasms: a report of the Association for Molecular Pathology.
- Fusion peptides from oncogenic chimeric proteins as specific biomarkers of cancer.
- microRNA expression profiling identifies molecular signatures associated with anaplastic large cell Lymphoma.
- Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell Lymphoma: a Children's Oncology Group phase 1 consorti...
- Differential expression of aurora-A kinase in T-cell Lymphomas.
- Recurrent reciprocal RNA chimera involving YPEL5 and PPP1CB in chronic lymphocytic Leukemia.
- Image microarrays derived from tissue microarrays (IMA-TMA): New resource for computer-aided diagnostic algorithm development.
- Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone Lymphoma.
- NPM-ALK signals through glycogen synthase kinase 3β to promote oncogenesis.
- Concomitant BCR-ABL1 Translocation and JAK2V617F Mutation in Three Patients with Myeloproliferative Neoplasms.
- The B7 homologues and their receptors in hematologic malignancies.
- Conjugated Polyelectrolyte-Antibody Hybrid Materials for Highly Fluorescent Live Cell-Imaging.
- Sox17 expression confers self-renewal potential and fetal stem Cell characteristics upon adult hematopoietic progenitors.
- Anaplastic Lymphoma kinase-positive anaplastic large cell Lymphoma presenting as retroperitoneal fibrosis.
- Signet Ring Cell Lymphoma in a Patient With Elevated CA-125.
- Specificity of IRF4 translocations for primary cutaneous anaplastic large cell Lymphoma: a multicenter study of 204 skin biopsies.
- Spontaneous remission of congenital Acute myeloid leukemia with t(8;16)(p11;13).
- mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem Cells after Pten deletion.
- Expression of Grb2 distinguishes classical Hodgkin Lymphomas from primary mediastinal B-cell Lymphomas and other diffuse large B-cell Lymphomas.
- Immunomodulator agent-related lymphoproliferative Disorders.
- The proteomic signature of NPM/ALK reveals deregulation of multiple Cellular pathways.
- Commentary on the WHO 2008 classification of neoplasms arising from histiocytic and other accessory Cells.
- Commentary on the 2008 WHO classification of mature T- and NK-Cell neoplasms.
- Unraveling ALK signaling through phosphoproteomics.
- T Cell lymphoproliferative disorders associated with anti-tumor necrosis factor alpha antibody therapy for ulcerative colitis: literature summary.
- Apoptosis of t(14;18)-positive Lymphoma cells by a Bcl-2 interacting small molecule.
- Human Proteinpedia enables sharing of human protein data.
- Comprehensive identification of proteins in Hodgkin Lymphoma-derived Reed-Sternberg cells by LC-MS/MS.
- Chronic myeloid Leukemia as a secondary malignancy after ALK-positive anaplastic large cell lymphoma.
- NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell Lymphoma.
- Blastic transformation of low-grade follicular Lymphoma.
- Evaluation of enrichment techniques for mass spectrometry: identification of tyrosine phosphoproteins in cancer Cells.
- Mass spectrometry-based proteomic studies of human anaplastic large cell Lymphoma.
- Analytical characteristics of cleavable isotope-coded affinity tag-LC-tandem mass spectrometry for quantitative proteomic studies.
- Proteomic identification of oncogenic chromosomal translocation partners encoding chimeric anaplastic Lymphoma kinase fusion proteins.
- Re: Correlational of oral tongue cancer inversion with matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) expression, by Kim S-H, Cho NH, K...
- Analysis of BCL6-interacting proteins by tandem mass spectrometry.
- Annotated proteome of a human T-cell Lymphoma.
- Childhood and adolescent non-Hodgkin Lymphoma: new insights in biology and critical challenges for the future.
- Identification of proteins from formalin-fixed paraffin-embedded Cells by LC-MS/MS.
- State of the Art and Future Needs in Cytogenetic/Molecular Genetics/Arrays in childhood Lymphoma: summary report of workshop at the First International Symposium on ch...
- Proteomics in pathology research.
- Quantitative proteomic and transcriptional analysis of the response to the p38 mitogen-activated protein kinase inhibitor SB203580 in transformed follicular Lymphoma c...
- T-Cell posttransplant lymphoproliferative disorder occurring in a pediatric solid-organ transplant patient.
- Application of SELDI-TOF mass spectrometry for the identification of differentially expressed proteins in transformed follicular Lymphoma.
- The molecular pathology of primary immunodeficiencies.
- Utility of linearly amplified RNA for RT-PCR detection of chromosomal translocations: validation using the t(2;5)(p23;q35) NPM-ALK chromosomal translocation.
- BCL-2 is consistently expressed in hyperplastic Marginal zones of the spleen, abdominal lymph nodes, and ileal lymphoid tissue.
- Involvement of multiple signaling pathways in follicular Lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy.
- Comparative microarray analysis of gene expression during activation of human peripheral blood T Cells and leukemic Jurkat T Cells.
- Analysis of the PI-3-Kinase-PTEN-AKT pathway in human lymphoma and Leukemia using a cell line microarray.
- High-throughput analysis of protein/peptide complexes by immunoprecipitation and automated LC-MS/MS.
- 5'-(RACE) identification of rare ALK fusion partner in anaplastic large cell Lymphoma.
- T-cell/histiocyte-rich large B-cell Lymphoma: a heterogeneous entity with derivation from germinal center B cells.
- Expression of Skp2, a p27(Kip1) ubiquitin ligase, in malignant Lymphoma: correlation with p27(Kip1) and proliferation index.
- Microarray analysis of B-cell Lymphoma cell lines with the t(14;18).
- Fluorescence PCR quantification of cyclin D1 expression.
- Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2-MALT1 in MALT Lymphoma.
- The role of front-line anthracycline-containing chemotherapy regimens in peripheral T-cell Lymphomas.
- ALK-driven tumors and targeted therapy: focus on crizotinib.
- Phosphorylation of skeletal and cardiac muscle C-proteins by the catalytic subunit of cAMP-dependent protein kinase.
- Phosphorylation of bovine cardiac C-protein by protein kinase C.
- Difficult airway management in the intensive care unit: alternative techniques.
- Difficult airway management in the intensive care unit: practical guidelines.
- The use of the oesophageal Doppler monitor in the intensive care unit.
- Rdp1, a novel zinc finger protein, regulates the DNA damage response of rhp51(+) from Schizosaccharomyces pombe.
- The role of metalloproteinases and their inhibitors in hematological Disorders.
- Frequency of CYP2C9 variant alleles, including CYP2C9*13 in a Korean population and effect on glimepiride pharmacokinetics.
- Chilean miners: raising awareness of the plight of miners worldwide.
- Proteolytic activity of human non-Hodgkin's Lymphomas.
- The dual PI3K/mTOR inhibitor, NVP-BEZ235, is efficacious against follicular Lymphoma.
- Teaching pediatric laboratory medicine to pathology residents.
- TIMP-1 expression in anaplastic large cell Lymphoma is usually restricted to macrophages and only seldom observed in tumour cells.
- Tissue inhibitor of metalloproteinase-2 induces apoptosis in human T lymphocytes.
- Detection of the c-kit D816V mutation in Systemic mastocytosis by allele-specific PCR.
- Loss of Ubr1 promotes aneuploidy and accelerates B-cell Lymphomagenesis in TLX1/HOX11-transgenic mice.
- Dysregulated expression of mitotic regulators is associated with B-cell Lymphomagenesis in HOX11-transgenic mice.
- Primary Hodgkin's disease of the CNS in an immunocompetent patient: a case study and review of the literature.
- High expression of calcium-binding proteins, S100A10, S100A11 and CALM2 in anaplastic large cell Lymphoma.
- The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem Cells.
- Frequent cyclin D1 gene amplification and protein overexpression in oral epithelial dysplasias.
- Enhanced case detection for newly acquired hepatitis C infection: epidemiological findings and health service implications.
- Pathological findings in human autoimmune lymphoproliferative Syndrome.
- EBV-associated perianal Hodgkin's disease in an HIV-positive individual.
- Validation of cDNA microarray gene expression data obtained from linearly amplified RNA.
- A randomised controlled trial using mobile advertising to promote safer sex and sun safety to young people.
- Tissue inhibitor of metalloproteinases 1 regulation of interleukin-10 in B-cell differentiation and Lymphomagenesis.
- Using a surveillance System to identify and treat newly acquired hepatitis C infection.
- Precision Medicine for Diffuse Large B-cell Lymphoma.
Conditions Treated
- Acute Leukemia
- Anemia
- Antiphospholipid Syndrome (APS)
- Central Nervous System Lymphoma
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Doctors Specialties
- Hematology
- Hematopathology
- Molecular Genetic Pathology
- Pathology
Accepted Insurances
Hospital
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University of Michigan Hospitals and Health Centers
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1467522888 |
| Last Name Of The Provider | LIM |
| First Name Of The Provider | MEGAN |
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