Professor, Surgery, Tufts Medical Center
General Surgery
Dr. Michael L. Steer, MD
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Michael Steer is an expert in the field of General Surgery. He researched medicine at Duke University School of Medicine. Duke University School of Medicine is a top medical university. Duke University School of Medicine has a rank of 8 in research and a 29 in primary care He has 2 awards "Elected Member" and "Fellow (FACS)". Michael Steer is a published MD as well. He has 100 publications published. The latest was: Parallel secretion of digestive enzymes by the in vitro rabbit pancreas.
Publications
- Pharmacological inhibition of PAR2 with the pepducin P2pal-18S protects mice against acute experimental biliary pancreatitis.
- TNF-{alpha}-dependent Regulation of Acute Pancreatitis Severity by Ly-6Chi Monocytes in Mice.
- Surgeons' dispatch from Cange, Haiti.
- Biliary acute pancreatitis in mice is mediated by the G-protein-coupled cell surface bile acid receptor Gpbar1.
- Protease-activated receptor-2 exerts contrasting model-specific effects on acute experimental pancreatitis.
- Tumor progression locus-2 is a critical regulator of pancreatic and lung inflammation during acute pancreatitis.
- Cause-effect relationships between zymogen activation and other early events in secretagogue-induced acute pancreatitis.
- Calcium dependence of proteinase-activated receptor 2 and cholecystokinin-mediated amylase secretion from pancreatic acini.
- Protection against acute pancreatitis by activation of protease-activated receptor-2.
- Inhibition of cyclooxygenase-2 ameliorates the severity of pancreatitis and associated lung injury.
- In vivo evidence for the role of GM-CSF as a mediator in acute pancreatitis-associated lung injury.
- Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.
- Thermal stress-induced HSP70 mediates protection against intrapancreatic trypsinogen activation and acute pancreatitis in rats.
- Cell biology and genetics of root hair formation in Arabidopsis thaliana.
- Inhibitory effects of sodium and other monovalent cations on human platelet adenylate cyclase.
- Evidence for high and low affinity alpha 2-receptors. Comparison of [3H]norepinephrine and [3H]phentolamine binding to human platelet membranes.
- Regulation of human platelet adenylate cyclase by epinephrine, prostaglandin E1, and guanine nucleotides. Evidence for separate guanine nucleotide sites mediating stim...
- Preparation and characterization of hormone-sensitive, resealed erythrocyte ghosts.
- The control of adenylate cyclase by calcium in turkey erythrocyte ghosts.
- Endoscopically assisted direct pancreatic function testing: a simplified technique.
- A Rosetta Stone for chronic pancreatitis?
- Preoperative localization of nonpalpable breast lesions demonstrated by mammography.
- Inter-relations between beta-adrenergic receptors, adenylate cyclase and calcium.
- Diagnostic procedures in gastrointestinal hemorrhage.
- Classification and pathogenesis of pancreatitis.
- Chronic pancreatitis: a complication of systemic lupus erythematosus.
- The effects of ethionine administration and choline deficiency on protein carboxymethylase activity in mouse pancreas.
- The metal specificity of mammalian -amylase as revealed by enzyme activity and structural probes.
- The allosteric activation of mammalian alpha-amylase by chloride.
- The use of helical CT and CT angiography to predict vascular involvement from pancreatic cancer: correlation with findings at surgery.
- Pathogenesis of acute pancreatitis.
- Combined gastric and ileocecal toxicity (serpiginous ulcers) after oral kayexalate in sorbital therapy.
- Workshop on experimental pancreatitis.
- Direct effects of ethanol on exocrine secretion from the in vitro rabbit pancreas.
- Effects of ethionine on digestive enzyme synthesis and discharge by mouse pancreas.
- MR cholangiopancreatography (MRCP) in diagnosis of afferent loop syndrome presenting as cholangitis.
- Impact of CT on diagnosis and management of acute abdomen in patients initially treated without surgery.
- Pancreatic cystic lymphangioma in an adult.
- State-of-the-art ultrasonography is as accurate as helical computed tomography and computed tomographic angiography for detecting unresectable periampullary cancer.
- Is CT angiography sufficient for prediction of resectability of periampullary neoplasms?
- Pancreatitis. The role of lysosomes.
- Common bile duct biopsy with the Simpson atherectomy catheter.
- Protective effects of therapy with a protease and xanthine oxidase inhibitor in short form pancreatic biliary obstruction and ischemia in rats.
- Pancreatitis severity: who calls the shots?
- Parallel secretion of digestive enzymes by the in vitro rabbit pancreas.
- Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis.
- Proceedings: Parallel secretion of amylase, tryposinogen and chymotrypsinogen from the in vitro rabbit pancreas.
- Requirements for activation of trypsinogen and chymotrypsinogen in rabbit pancreatic juice.
- Diet-induced pancreatitis in mice: effect of glucagon on mortality and pancreatic function.
- Protease inhibitors and experimental acute hemorrhagic pancreatitis.
- Effects of glucagon on pancreatic content and secretion of amylase in mice.
- Chronic pancreatitis.
- Enhancement of pancreas and diagnosis of pancreatitis using manganese dipyridoxyl diphosphate.
- In vivo rat pancreatic acinar cell function during supramaximal stimulation with caerulein.
- Recent insights into the etiology and pathogenesis of acute biliary pancreatitis.
- Cyclosporin and chronic pancreatitis: a supermodel?
- Pancreatic secretion of lysosomal enzymes stimulated by intraduodenal instillation of a liquid meal in rabbits.
- In vivo and in vitro effects of the azidothymidine analog dideoxyinosine on the exocrine pancreas of the rat.
- Intracellular transport of pancreatic zymogens during caerulein supramaximal stimulation.
- How and where does acute pancreatitis begin?
- Regulation of pancreatic islet cell survival and replication by gamma-aminobutyric acid.
- Cholecystokinin/pancreozymin induces the parallel discharge of digestive enzymes from the in vitro rabbit pancreas.
- The cell biology of experimental pancreatitis.
- Pathobiology of experimental acute pancreatitis.
- Search for the trigger mechanism of pancreatitis.
- Protective effects of PGE2 on diet-induced acute pancreatitis in mice.
- Failure of extracellular digestive enzymes to alter in vitro secretion by rat pancreas.
- Experimental acute pancreatitis in mice. Protective effects of glucagon.
- Secretion of lysosomal and digestive enzymes into pancreatic juice under physiological and pathological conditions in rabbits.
- Subcellular redistribution of lysosomal enzymes during caerulein-induced pancreatitis.
- Evaluation of necrotizing pancreatitis in the opossum by dynamic contrast-enhanced computed tomography: correlation between radiographic and morphologic changes.
- Secretagogue-induced changes in intracellular pH and amylase release in mouse pancreatic acini.
- Effect of cerulein hyperstimulation on the paracellular barrier of rat exocrine pancreas.
- Repetitive short-term obstructions of the common bile-pancreatic duct induce severe acute pancreatitis in the opossum.
- Inhibition of ubiquitin-proteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide.
- Lysosomal enzymes and pancreatitis.
- Diminished agonist-stimulated inositol trisphosphate generation blocks stimulus-secretion coupling in mouse pancreatic acini during diet-induced experimental pancreati...
- Inositol trisphosphate production and amylase secretion in mouse pancreatic acini.
- A simple and efficient method of measuring in vitro amylase secretion by dispersed pancreatic acini.
- Intracellular Ca2+ levels and amylase secretion in Quin 2-loaded mouse pancreatic acini.
- Relationship between pancreatitis and lung diseases.
- Intravenous contrast medium does not increase the severity of acute necrotizing pancreatitis in the opossum.
- Early events in acute pancreatitis.
- Effects of chloroquine and methylamine on lysosomal enzyme secretion by rat pancreas.
- A plasma protease which is expressed during supramaximal stimulation causes in vitro subcellular redistribution of lysosomal enzymes in rat exocrine pancreas.
- Frank Brooks memorial Lecture: The early intraacinar cell events which occur during acute pancreatitis.
- Role of oxygen-derived free radicals in diet-induced hemorrhagic pancreatitis in mice.
- Inositol trisphosphate-independent agonist-stimulated calcium influx in rat pancreatic acinar cells.
- Effects of a choline-deficient ethionine-supplemented diet on phospholipase C activity in mouse pancreatic acinar cell membranes and in electropermeabilized mouse panc...
- Effects of cycloheximide on pancreatic endonuclease activity, apoptosis, and severity of acute pancreatitis.
- Early ductal decompression prevents the progression of biliary pancreatitis: an experimental study in the opossum.
- The role of oxygen-derived free radicals in two models of experimental acute pancreatitis: effects of catalase, superoxide dismutase, dimethylsulfoxide, and allopurinol.
- Acute necrotizing pancreatitis in the opossum: earliest morphological changes involve acinar cells.
- Failure of a potent cholecystokinin antagonist to protect against diet-induced pancreatitis in mice.
- Stimulation of pancreatic growth by cholecystokinin is mediated by high affinity receptors on rat pancreatic acinar cells.
- Inositol trisphosphate independent increase of intracellular free calcium and amylase secretion in pancreatic acini.
- Pancreatic duct obstruction in rabbits causes digestive zymogen and lysosomal enzyme colocalization.
- Water immersion stress induces heat shock protein 60 expression and protects against pancreatitis in rats.
- Luminal endocytosis and intracellular targeting by acinar cells during early biliary pancreatitis in the opossum.
Schools
Duke University
King Co Hospital
Beth Israel Harvard University Hospital
Calif Med Center
Doctors Specialties
- General Surgery
Accepted Insurances
Awards
- Elected Member
- Fellow (FACS)
Education
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Beth Israel Deaconess Medical Center -
UCSF -
Harborview Medical Center -
Duke University School of Medicine
Hospital
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Beth Israel Deaconess Medical Center
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