Professor, Psychiatry, UCSD School of Medicine
Psychiatry
Dr. Neal R. Swerdlow, MD
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Neal R. Swerdlow is an expert in the field of Psychiatry. He went to University of California San Diego School of Medicine. University of California San Diego School of Medicine is ranked 17/19 in Research/PrimaryCare. Neal Swerdlow is a published doctor. He published 101 publications, including: 'Seroquel, clozapine and chlorpromazine restore sensorimotor gating in ketamine-treated rats.'
Publications
- Attention/vigilance in schizophrenia: Performance results from a large multi-site study of the Consortium on the Genetics of Schizophrenia (COGS).
- Factor structure and heritability of endophenotypes in schizophrenia: Findings from the Consortium on the Genetics of Schizophrenia (COGS-1).
- Robust differences in antisaccade performance exist between COGS schizophrenia cases and controls regardless of recruitment strategies.
- California Verbal Learning Test-II performance in schizophrenia as a function of ascertainment strategy: Comparing the first and second phases of the Consortium on the...
- Validation of mismatch negativity and P3a for use in multi-site studies of schizophrenia: Characterization of demographic, clinical, cognitive, and functional correlat...
- Paternal age of schizophrenia probands and endophenotypic differences from unaffected siblings.
- Forebrain gene expression predicts deficits in sensorimotor gating after isolation rearing in male rats.
- Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network.
- Coupling of gene expression in medial prefrontal cortex and nucleus accumbens after neonatal ventral hippocampal lesions accompanies deficits in sensorimotor gating an...
- Opposite effects of tolcapone on amphetamine-disrupted startle gating in low vs. high COMT-expressing rat strains.
- Sex Differences in Familiality Effects on Neurocognitive Performance in Schizophrenia.
- Towards medication-enhancement of cognitive interventions in schizophrenia.
- Update: Studies of prepulse inhibition of startle, with particular relevance to the pathophysiology or treatment of Tourette Syndrome.
- Characterization of neurophysiologic and neurocognitive biomarkers for use in genomic and clinical outcome studies of schizophrenia.
- Fronto-temporal-mesolimbic gene expression and heritable differences in amphetamine-disrupted sensorimotor gating in rats.
- Disentangling early sensory information processing deficits in schizophrenia.
- Association analysis of 94 candidate genes and schizophrenia-related endophenotypes.
- Stereochemical and neuroanatomical selectivity of pramipexole effects on sensorimotor gating in rats.
- Disparate effects of pramipexole on locomotor activity and sensorimotor gating in Sprague-Dawley rats.
- Are we studying and treating schizophrenia correctly?
- Analysis of 94 Candidate Genes and 12 Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia.
- Probing the molecular basis for an inherited sensitivity to the startle-gating disruptive effects of apomorphine in rats.
- Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS study.
- Electroencephalography (EEG) and event-related potentials (ERPs) with human participants.
- Parametric approaches towards understanding the effects of the preferential D3 receptor agonist pramipexole on prepulse inhibition in rats.
- Using prepulse inhibition to detect functional D3 receptor antagonism: effects of WC10 and WC44.
- Effects of the first prepulse on the blink response to a startling noise.
- Abnormal auditory N100 amplitude: a heritable endophenotype in first-degree relatives of schizophrenia probands.
- Quinelorane, a dopamine D3/D2 receptor agonist, reduces prepulse inhibition of startle and ventral pallidal GABA efflux: time course studies.
- Strain differences in the gating-disruptive effects of apomorphine: relationship to gene expression in nucleus accumbens signaling pathways.
- A novel rat strain with enhanced sensitivity to the effects of dopamine agonists on startle gating.
- Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia.
- Preattentive sensory processing as indexed by the MMN and P3a brain responses is associated with cognitive and psychosocial functioning in healthy adults.
- Prepulse inhibition and P50 suppression are both deficient but not correlated in schizophrenia patients.
- Strain differences in the disruption of prepulse inhibition of startle after systemic and intra-accumbens amphetamine administration.
- The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration.
- Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures.
- Gamma band oscillations reveal neural network cortical coherence dysfunction in schizophrenia patients.
- Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function.
- Antipsychotic effects on prepulse inhibition in normal 'low gating' humans and rats.
- Heritable differences in the dopaminergic regulation of behavior in rats: relationship to D2-like receptor G-protein function.
- Effects of background and prepulse characteristics on prepulse inhibition and facilitation: implications for neuropsychiatric research.
- Convergence and divergence in the neurochemical regulation of prepulse inhibition of startle and N40 suppression in rats.
- Prepulse-elicited motor reactions do not differ between schizophrenia patients and control subjects.
- Preclinical models relevant to Tourette syndrome.
- Reduced startle gating after D1 blockade: effects of concurrent D2 blockade.
- Tourette syndrome: current controversies and the battlefield landscape.
- Female schizophrenia patients have prepulse inhibition deficits.
- Neurochemical analysis of rat strain differences in the startle gating-disruptive effects of dopamine agonists.
- Reduced N-acetylaspartate in the temporal cortex of rats reared in isolation.
- Weak prepulses inhibit but do not elicit startle in rats and humans.
- Sensitivity to drug effects on prepulse inhibition in inbred and outbred rat strains.
- Amphetamine effects on prepulse inhibition across-species: replication and parametric extension.
- Heritable differences in the effects of amphetamine but not DOI on startle gating in albino and hooded outbred rat strains.
- Sensitivity to sensorimotor gating-disruptive effects of apomorphine in two outbred parental rat strains and their F1 and N2 progeny.
- Quetiapine produces a prolonged reversal of the sensorimotor gating-disruptive effects of basolateral amygdala lesions in rats.
- Isolation rearing-induced deficits in prepulse inhibition and locomotor habituation are not potentiated by water deprivation.
- Prestimulus effects on startle magnitude: sensory or motor?
- Genetic differences in startle gating-disruptive effects of apomorphine: evidence for central mediation.
- Is There an Association between Advanced Paternal Age and Endophenotype Deficit Levels in Schizophrenia?
- Effects of alpha-flupenthixol and naloxone on CRF-induced locomotor activation.
- Behavioral changes following central injection of cysteamine in rats.
- Aggressive treatment of a patient with the acquired immunodeficiency syndrome.
- Effects of pergolide on sensorimotor gating of the startle reflex in rats.
- Sensitivity to the dopaminergic regulation of prepulse inhibition in rats: evidence for genetic, but not environmental determinants.
- Tactile prepuff inhibition of startle in children with Tourette's syndrome: in search of an "fMRI-friendly" startle paradigm.
- Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies.
- Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges.
- Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review.
- Neuropathology in Tourette syndrome: an update.
- Lesion size and amphetamine hyperlocomotion after neonatal ventral hippocampal lesions: more is less.
- Obsessive-compulsive disorder and tic syndromes.
- Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia.
- Regulation of sensorimotor gating in rats by hippocampal NMDA: anatomical localization.
- Matching strategies for drug studies of prepulse inhibition in humans.
- Animal models of deficient sensorimotor gating: what we know, what we think we know, and what we hope to know soon.
- Regulation of sensorimotor gating of the startle reflex by serotonin 2A receptors. Ontogeny and strain differences.
- "Early" and "late" effects of sustained haloperidol on apomorphine- and phencyclidine-induced sensorimotor gating deficits.
- Effects of caffeine on sensorimotor gating of the startle reflex in normal control subjects: impact of caffeine intake and withdrawal.
- Modulation of the startle response and startle laterality in relatives of schizophrenic patients and in subjects with schizotypal personality disorder: evidence of inh...
- Distributed neurodegenerative changes 2-28 days after ventral hippocampal excitotoxic lesions in rats.
- Toward understanding the biology of a complex phenotype: rat strain and substrain differences in the sensorimotor gating-disruptive effects of dopamine agonists.
- Hippocampal lesions enhance startle gating-disruptive effects of apomorphine in rats: a parametric assessment.
- Ontogeny of phencyclidine and apomorphine-induced startle gating deficits in rats.
- Preliminary findings with a new Vietnamese Stroop test.
- Sex differences in sensorimotor gating of the human startle reflex: all smoke?
- Attitudes toward psychiatry as a prospective career among students entering medical school.
- Is there a "subcortical" profile of attentional dysfunction? A comparison of patients with Huntington''s and Parkinson''s diseases on a global-local focused attention ...
- Visuospatial priming and stroop performance in patients with obsessive compulsive disorder.
- Cross-species studies of sensorimotor gating of the startle reflex.
- Effects of LU-111995 in three models of disrupted prepulse inhibition in rats.
- Effects of sustained phencyclidine exposure on sensorimotor gating of startle in rats.
- Effects of sustained cocaine exposure on sensorimotor gating of startle in rats.
- Symptom correlates of prepulse inhibition deficits in male schizophrenic patients.
- Saccadic performance characteristics and the behavioural neurology of Tourette's syndrome.
- Enhanced visual latent inhibition in obsessive-compulsive disorder.
- Prepulse inhibition and habituation of the startle response are stable neurobiological measures in a normal male population.
- Seroquel, clozapine and chlorpromazine restore sensorimotor gating in ketamine-treated rats.
- What role models? Commentary on Robbins'' homology in behavioural pharmacology: an approach to animal models of human cognition.
- Towards a cross-species pharmacology of sensorimotor gating: effects of amantadine, bromocriptine, pergolide and ropinirole on prepulse inhibition of acoustic startle ...
Schools
University of California At San Diego
Doctors Specialties
- Psychiatry
Accepted Insurances
- First Health (Coventry Health Care) PPO
- Kaiser PHCS Network PPO
- MultiPlan PPO
- PHCS Network PPO
Education
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University of California San Diego School of Medicine
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