Physician
Oncology
Dr. Patrick Hwu, MD
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Patrick is an expert in the field of Oncology. He received 5 awards: "America's Top Doctors", "Top Doctors:SE Texas", "America's Top Doctors for Cancer", "Elected Member" and "Whos Who in Medicine and Healthcare". Patrick is also a published doctor. He has 44 paper published. The most recent paper is: De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute. Patrick is registered with Medicare and accepts Medicare payments.
Publications
- Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
- Correlation of BRAF Mutation Status in Circulating-Free DNA and Tumor and Association with Clinical Outcome across Four BRAFi and MEKi Clinical Trials.
- Epithelial-mesenchymal transition is associated with a distinct tumor microenvironment including elevation of inflammatory signals and multiple immune checkpoints in l...
- Intrathecal Administration of Tumor-Infiltrating Lymphocytes Is Well Tolerated in a Patient with Leptomeningeal Disease from Metastatic Melanoma: A Case Report.
- Reduced adenosine-to-inosine miR-455-5p editing promotes Melanoma growth and metastasis.
- BRAF(V600E) co-opts a conserved MHC class I internalization pathway to diminish antigen presentation and CD8+ T-cell recognition of Melanoma.
- Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced Melanoma.
- Phase I study of pazopanib and vorinostat: a therapeutic approach for inhibiting mutant p53-mediated angiogenesis and facilitating mutant p53 degradation.
- Manipulating the tumor microenvironment ex vivo for enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy.
- Effective Innate and Adaptive AntiMelanoma Immunity through Localized TLR7/8 Activation.
- Phase I/II Study of the Antibody-Drug Conjugate Glembatumumab Vedotin in Patients With Advanced Melanoma.
- Complete loss of PTEN protein expression correlates with shorter time to Brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations.
- Tumor-Infiltrating Lymphocyte Therapy for Melanoma: Rationale and Issues for Further Clinical Development.
- PD-L1 Expression in Triple-Negative Breast Cancer.
- Phase I trial of biochemotherapy with cisplatin, temozolomide, and dose escalation of nab-paclitaxel combined with interleukin-2 and interferon-α in patients with meta...
- Pathways and therapeutic targets in Melanoma.
- Antagonist Antibodies to PD-1 and B7-H1 (PD-L1) in the Treatment of Advanced Human Cancer--Letter.
- Clinical characteristics and outcomes with specific BRAF and NRAS mutations in patients with metastatic Melanoma.
- Chemical Castration of Melanoma Patients Does Not Increase the Frequency of Tumor-specific CD4 and CD8 T Cells After Peptide Vaccination.
- Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion.
- Advances in the development of Cancer immunotherapies.
- Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against Cancer.
- Phase II Study of the MEK1/MEK2 Inhibitor Trametinib in Patients With Metastatic BRAF-Mutant Cutaneous Melanoma Previously Treated With or Without a BRAF Inhibitor.
- Strong emerging rationale for combining oncogene-targeted agents with immunotherapy.
- BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice.
- BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma.
- Specific Lymphocyte Subsets Predict Response to Adoptive Cell Therapy Using Expanded Autologous Tumor-Infiltrating Lymphocytes in Metastatic Melanoma Patients.
- Broad Cross-Presentation of the Hematopoietically Derived PR1 Antigen on Solid Tumors Leads to Susceptibility to PR1-Targeted Immunotherapy.
- Antitumor T-cell responses contribute to the effects of dasatinib on c-KIT mutant murine mastocytoma and are potentiated by anti-OX40.
- Differential Expression of the G-Protein-Coupled Formyl Peptide Receptor in Melanoma Associates With Aggressive Phenotype.
- Harnessing the Power of the Immune System to Target Cancer.
- New insights on the role of CD8(+)CD57(+) T-cells in Cancer.
- A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy.
- BRAF, NRAS and KIT sequencing Analysis of spindle cell melanoma.
- Risk of intracranial hemorrhage with anticoagulation therapy in melanoma patients with Brain metastases.
- Advances in the treatment of metastatic Melanoma: adoptive T-cell therapy.
- Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic Melanoma: current status and future outlook.
- Biochemotherapy in patients with advanced head and neck mucosal Melanoma.
- Analysis of the intratumoral adaptive immune response in well differentiated and dedifferentiated retroperitoneal liposarcoma.
- Activation and Propagation of Tumor-infiltrating Lymphocytes on Clinical-grade Designer Artificial Antigen-presenting Cells for Adoptive Immunotherapy of Melanoma.
- Co-Stimulation through 4-1BB/CD137 Improves the Expansion and Function of CD8(+) Melanoma Tumor-Infiltrating Lymphocytes for Adoptive T-Cell Therapy.
- Next generation sequencing of exceptional responders with BRAF-mutant Melanoma: implications for sensitivity and resistance.
- De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute.
Schools
Medical College of Pennsylvania
Clinical Center At The Nih
Procedures Preformed
- Cardiac MRI (Magnetic Resonance Imaging) of Heart or Chest
- Thoracentesis
Conditions Treated
- Adrenal Gland Cancer
- Anal and Rectal Cancer
- Anemia
- Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
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Doctors Specialties
- Medical Oncology
- Oncology
Accepted Insurances
- Assurant Health
- Blue Card PPO
- Blue Choice
- CHAMPVA
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- LocalPlus
- Open Access Plus
- Commercial Insurance Company
- Coventry Health Care
- First Health (Coventry Health Care) PPO
- GEHA
- Choice Care PPO
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- MVP Health Care
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
Awards
- America's Top Doctors
- Top Doctors:SE Texas
- America's Top Doctors for Cancer
- Elected Member
- Whos Who in Medicine and Healthcare
Education
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National Institutes of Health Clinical Center -
Johns Hopkins University
Hospital
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University of Texas M.D. Anderson Cancer Center
Drug Facts
| NPI NUMBER | 1407949944 | |
| NPPES Provider LastName | HWU | |
| NPPES Provider FirstName | PATRICK | |
| NPPES Provider ZIPCode | 770304009 | |
| NPPES Provider State | TX | |
| Specialty Description | Medical Oncology | |
| Total Claim Count | 60.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1407949944 |
| Last Name Of The Provider | HWU |
| First Name Of The Provider | PATRICK |
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