Professor of Pediatrics, University Mass School of Medicine
Pediatric Hematology & Oncology
Dr. Peter E. Newburger, MD
|
|
Give Review
Dr. Peter E. Newburger works in the field of Pediatric Hematology & Oncology. He graduated from Harvard Medical School. Harvard Medical School is a one of the best medicals schools. Harvard Medical School is ranked 1 in research and 12 in primary care medicine He received awards:"Regional Top Doctor", "Elected Member", "Deputy editor", "Phi Beta Kappa" and "Alpha Omega Alpha". Peter Newburger has written publications. He has 99 publications published with PubMed. The lastest publication is: 'Esophagitis due to adriamycin and radiation therapy for childhood malignancy.'
Publications
- Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9.
- Use of granulocyte colony-stimulating factor during pregnancy in women with chronic Neutropenia.
- The diversity of mutations and clinical outcomes for ELANE-associated Neutropenia.
- Long intergenic non-coding RNA HOTAIRM1 regulates cell cycle progression during myeloid maturation in NB4 human promyelocytic leukemia cells.
- Evaluation and management of patients with isolated Neutropenia.
- Novel deletion of RPL15 identified by array-comparative genomic hybridization in Diamond-Blackfan anemia.
- HOX antisense lincRNA HOXA-AS2 is an apoptosis repressor in all trans retinoic acid treated NB4 promyelocytic leukemia cells.
- Advances in understanding the pathogenesis of HLH.
- Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan an...
- Hemophagocytic lymphohistiocytosis with MUNC13-4 gene mutation or reduced natural killer cell function prior to onset of childhood leukemia.
- Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease.
- Cyclic Neutropenia and severe congenital Neutropenia in patients with a shared ELANE mutation and paternal haplotype: evidence for phenotype determination by modifying...
- X chromosome-wide analyses of genomic DNA methylation states and gene expression in male and female neutrophils.
- Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia.
- Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS).
- Cyclic Neutropenia in animals.
- A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster.
- Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients.
- Toll-like receptor-mediated activation of neutrophils by influenza A virus.
- Essential role of nuclear factor-kappaB for NADPH oxidase activity in normal and anhidrotic ectodermal dysplasia leukocytes.
- The American Society of Pediatric Hematology/Oncology distinguished career award goes to Laurence A. Boxer, MD.
- IL6 to the rescue.
- Mosaic tetraploidy and transient GFI1 mutation in a patient with severe chronic Neutropenia.
- Up-regulation of NADPH oxidase components and increased production of interferon-gamma by leukocytes from sickle cell disease patients.
- A molecular classification of congenital Neutropenia syndromes.
- RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells.
- Temporal evolution of gene expression in rat carotid artery following balloon angioplasty.
- A limited number of genes are involved in the differentiation of germinal center B cells.
- Nuclease sensitive element binding protein 1 gene disruption results in early embryonic lethality.
- Nuclease sensitive element binding protein 1 associates with the selenocysteine insertion sequence and functions in mammalian selenoprotein translation.
- Chronic granulomatous disease in Latin American patients: clinical spectrum and molecular genetics.
- Disorders of neutrophil number and function.
- The effect of IFN-gamma and TNF-alpha on the NADPH oxidase system of human colostrum macrophages, blood monocytes, and THP-1 cells.
- The role of toll-like receptors in herpes simplex infection in neonates.
- Hematology and oncology.
- A panorama of lineage-specific transcription in hematopoiesis.
- p47(phox) PX domain of NADPH oxidase targets cell membrane via moesin-mediated association with the actin cytoskeleton.
- Lineage specificity of gene expression patterns.
- Association of glucose-6-phosphate dehydrogenase deficiency and X-linked chronic granulomatous disease in a child with anemia and recurrent infections.
- Gene expression in mature neutrophils: early responses to inflammatory stimuli.
- The effect of IFN-gamma and TNF-alpha on the eosinophilic differentiation and NADPH oxidase activation of human HL-60 clone 15 cells.
- Gene expression in human neutrophils during activation and priming by bacterial lipopolysaccharide.
- Genomic and proteomic analysis of the myeloid differentiation program: global analysis of gene expression during induced differentiation in the MPRO cell line.
- Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils.
- Adolescents with cancer: access to clinical trials and age-appropriate care.
- Local arterial nanoparticle delivery of siRNA for NOX2 knockdown to prevent restenosis in an atherosclerotic rat model.
- The human NADPH oxidase: primary and secondary defects impairing the respiratory burst function and the microbicidal ability of phagocytes.
- Acute lymphocytic leukemia with eosinophilia and unusual karyotype.
- Superoxide release and cellular gluthatione peroxidase activity in leukocytes from children with persistent asthma.
- Prenatal diagnosis of chronic granulomatous disease.
- Improved fluorescent staining of interphase nuclei for prenatal diagnosis.
- Esophagitis due to adriamycin and radiation therapy for childhood malignancy.
- Esophagitis induced by combined radiation and adriamycin.
- Constitutive and inducible granulocyte-macrophage functions in mouse, rat, and human myeloid leukemia-derived continuous tissue culture lines.
- Functional changes in human leukemic cell line HL-60. A model for myeloid differentiation.
- O2- production by B lymphocytes lacking the respiratory burst oxidase subunit p47phox after transfection with an expression vector containing a p47phox cDNA.
- Human immunodeficiency virus type 1-infected HL-60 cells are capable of both monocytic and granulocytic differentiation.
- In vitro regulation of human phagocyte cytochrome b heavy and light chain gene expression by bacterial lipopolysaccharide and recombinant human cytokines.
- Chronic granulomatous disease presenting in a 69-year-old man.
- Measurement of superoxide release in the phagovacuoles of immune complex-stimulated human neutrophils.
- Restoration of phagocyte function by interferon-gamma in X-linked chronic granulomatous disease occurs at the level of a progenitor cell.
- Isolation and chromosomal localization of the human glutathione peroxidase gene.
- Simultaneous flow cytometric measurements of cytoplasmic Ca++ and membrane potential changes upon FMLP exposure as HL-60 cells mature into granulocytes: using [Ca++]in...
- Relationships between the cell cycle and the expression of c-myc and transferrin receptor genes during induced myeloid differentiation.
- Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location.
- Infection of hematopoietic and stromal cells in human continuous bone marrow cultures by a retroviral vector containing the neomycin resistance gene.
- Differentiation of human hematopoietic cells increases expression of a gene transferred by a retroviral vector.
- Post-transcriptional regulation of glutathione peroxidase gene expression by selenium in the HL-60 human myeloid cell line.
- Recombinant interferon gamma augments phagocyte superoxide production and X-chronic granulomatous disease gene expression in X-linked variant chronic granulomatous dis...
- Partial correction of the phagocyte defect in patients with X-linked chronic granulomatous disease by subcutaneous interferon gamma.
- Cellular and molecular effects of recombinant interferon gamma in chronic granulomatous disease.
- Induction of phagocyte cytochrome b heavy chain gene expression by interferon gamma.
- New perspectives in chronic granulomatous disease.
- Marrow donors and international cooperation.
- Chediak-Higashi syndrome: studies in long-term bone marrow culture.
- Modulation of mononuclear phagocyte cytotoxicity by alpha-tocopherol (vitamin E).
- Relationships between in vitro selenium supply, glutathione peroxidase activity, and phagocytic function in the HL-60 human myeloid cell line.
- Characterization of a spontaneous mutation to a beta-thalassemia allele.
- Variant chronic granulomatous disease: modulation of the neutrophil defect by severe infection.
- Neutrophil defect associated with malignant infantile osteopetrosis.
- Biochemical and morphological characterization of basophilic leukocytes from two patients with myelogenous leukemia.
- Expression of the X-CGD gene during induced differentiation of myeloid leukemia cell line HL-60.
- Glutathione peroxidase protein. Absence in selenium deficiency states and correlation with enzymatic activity.
- Changes in superoxide dismutase, catalase, and the glutathione cycle during induced myeloid differentiation.
- Cloning the gene for the inherited disorder chronic granulomatous disease on the basis of its chromosomal location.
- Pseudomonas cepacia pneumonia in chronic granulomatous disease.
- Hapten-specific IgE antibody responses in mice. IV. Evidence for distinctive sensitivities of IgE and IgG B lymphocytes to the regulatory influence of T cells.
- Hapten-specific IgE antibody responses in mice. 3. Establishment of parameters for generation of helper T cell function regulating the primary and secondary responses ...
- Potentiation of helper T cell function in IgE antibody responses by bacterial lipolysaccharide (LPS).
- Characterization of an immune response gene in mice controlling IgE and IgM antibody responses to ragweed pollen extract and its 2,4-dinitrophenylated derivative.
- Studies on low-dose hydroxyethyl starch leukapheresis. Rate of elimination of HES in vivo and function of the harvested granulocytes in vitro.
- Activity and activation of the granulocyte superoxide-generating system.
- NAD(P)H-dependent superoxide production by phagocytic vesicles from guinea pig and human granulocytes.
- Dissociation of opsonized particle phagocytosis and respiratory burst activity in an Epstein-Barr virus-infected myeloid cell line.
- Chronic granulomatous disease. Expression of the metabolic defect by in vitro culture of bone marrow progenitors.
- Chronic pain: principles of management.
- Functionally deficient differentiation of HL-60 promyelocytic leukemia cells induced by phorbol myristate acetate.
- Splenic progenitors aid in maintaining high neutrophil numbers at sites of sterile chronic inflammation.
Schools
Harvard Medical School
Chldns Hospital Med Center
Conditions Treated
- Neutropenia
Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Blue Card PPO
- BlueConnect HMO
- Blue with Managed Care Behavioral Health HMO
- Preferred Blue PPO
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- LocalPlus
- Open Access Plus
- GHI PPO
- Fallon Community Health Plan
- First Health (Coventry Health Care) PPO
- Medicare MCR
- MultiPlan PPO
- PHCS Network PPO
- Network Health
- Tufts PPO
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
Awards
- Regional Top Doctor
- Elected Member
- Deputy editor
- Phi Beta Kappa
- Alpha Omega Alpha
Education
-
Boston Children's Hospital -
Harvard Medical School
Hospital
-
UMass Memorial Medical Center
Helpful Reviews
Similar Doctors
|
|
Dr. Christopher P. Keuker, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Indrani Malkani, MB
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Martha I. Sacoto, MD
This Doctor is OpenDoctor Recommended.
|