Nesbitt Chair and Head, Department of Medicine, University of Minnesota Medical School
Nephrology
Dr. Peter Igarashi, MD
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Dr. Peter Igarashi works in the field of Nephrology. He graduated from David Geffen School of Medicine at UCLA. David Geffen School of Medicine at UCLA is one of the top medical schools in the US. David Geffen School of Medicine at UCLA is ranked 13/7 in Research/PrimaryCare. He received awards:"Elected Member" and "Fellow (ASNF)". Doctor Peter Igarashi, MD has written publications. He has 95 publications published with PubMed. The lastest paper is: 'Immunochemical characterization of Na+/H+ exchanger isoform NHE4.' He accepts Medicare.
Publications
- Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1.
- Tissue-specific regulation of the Pkhd1 (ARPKD) gene promoter.
- Filling the Holes in Cystic Kidney Disease Research.
- Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic Kidney disease.
- miR-17~92 miRNA cluster promotes Kidney cyst growth in polycystic Kidney disease.
- Zyxin regulates migration of Renal epithelial cells through activation of hepatocyte nuclear factor-1β
- Generation and characterization of KsprtTA and KsptTA transgenic mice.
- Inducible expression of kallikrein in Renal tubular cells protect mice from spontaneous lupus nephritis.
- MicroRNAs Regulate Renal Tubule Maturation through Modulation of Pkd1.
- Tubule-specific ablation of endogenous β-catenin aggravates Acute kidney injury in mice.
- In utero diethylstilbestrol (DES) exposure alters Hox gene expression in the developing müllerian system.
- Uncompensated polyuria in a mouse model of Bartter's syndrome.
- The basic-helix-loop-helix protein pod1 is critically important for Kidney and lung organogenesis.
- Ksp-cadherin gene promoter. II. Kidney-specific activity in transgenic mice.
- Ksp-cadherin gene promoter. I. Characterization and Renal epithelial cell-specific activity.
- Sex steroids mediate HOXA11 expression in the human peri-implantation endometrium.
- Immunochemical characterization of Na+/H+ exchanger isoform NHE4.
- cDNA cloning and chromosomal localization of the human and mouse isoforms of Ksp-cadherin.
- HOXA10 is expressed in response to sex steroids at the time of implantation in the human endometrium.
- Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed in mesenchymal and glomerular epithelial cells in the developing Kidney.
- A conserved Hox axis in the mouse and human female reproductive system: late establishment and persistent adult expression of the Hoxa cluster genes.
- Antisense oligonucleotides to Cux-1, a Cut-related homeobox gene, cause increased apoptosis in mouse embryonic Kidney cultures.
- A unique variant of a homeobox gene related to Drosophila cut is expressed in mouse testis.
- Expression of a cut-related homeobox gene in developing and polycystic mouse Kidney.
- Primary structure, neural-specific expression, and chromosomal localization of Cux-2, a second murine homeobox gene related to Drosophila cut.
- Cloning and Kidney cell-specific activity of the promoter of the murine renal Na-K-C1 cotransporter gene.
- Localization of the Renal Na-K-Cl cotransporter gene (Slc12a1) on mouse chromosome 2.
- NHE3: a Na+/H+ exchanger isoform of Renal brush border.
- Transcription factors and apoptosis in Kidney development.
- Isolation and cDNA cloning of Ksp-cadherin, a novel Kidney-specific member of the cadherin multigene family.
- Phylogenetically conserved sequences in the promoter of the rabbit sodium-hydrogen exchanger isoform 1 gene (NHE1/SLC9A1).
- Cloning, embryonic expression, and alternative splicing of a murine Kidney-specific Na-K-Cl cotransporter.
- Arginine-specific modification of rabbit muscle phosphoglucose isomerase: differences in the inactivation by phenylglyoxal and butanedione and in the protection by sub...
- Unsuspected mediastinal hematoma diagnosed by computed tomography.
- Plasma hippurate in renal Failure: high-performance liquid chromatography method and clinical application.
- Preparation of 6-125I-labeled amiloride derivatives.
- Covalent modification of the Renal Na+/H+ exchanger by N,N'-dicyclohexylcarbodiimide.
- Identification and purification of a renal amiloride-binding protein With properties of the Na+-H+ exchanger.
- Cloning of cDNAs encoding a rabbit renal brush border membrane protein immunologically related to band 3. Sequence similarity With microsomal dipeptidase.
- Isolation of putative voltage-gated epithelial K-channel isoforms from rabbit Kidney and LLC-PK1 cells.
- Cloning, sequence, and tissue distribution of a rabbit Renal Na+/H+ exchanger transcript.
- cDNA cloning and immunolocalization of a Na(+)-H+ exchanger in LLC-PK1 Renal epithelial cells.
- Molecular biology of Renal Na(+)-H+ exchangers.
- cDNA cloning and localization of a band 3-related protein from ileum.
- Effects of chronic metabolic Acidosis on Na(+)-H+ exchangers in LLC-PK1 renal epithelial cells.
- Immunocytochemical characterization of Na(+)-H+ exchanger isoform NHE-1 in rabbit Kidney.
- Genetic Basis of Prune Belly Syndrome: Screening for HNF1? Gene.
- Increased hedgehog signaling in postnatal Kidney results in aberrant activation of nephron developmental programs.
- Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic Kidney diseases.
- Primary cilia regulate mTORC1 activity and cell size through Lkb1.
- Smad2 protects against TGF-beta/Smad3-mediated Renal fibrosis.
- Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathway.
- A mitotic transcriptional switch in polycystic Kidney disease.
- Loss of oriented cell division does not initiate cyst formation.
- Wnt9b signaling regulates planar cell polarity and Kidney tubule morphogenesis.
- Advances in the pathogenesis and treatment of polycystic Kidney disease.
- Collecting duct-specific Rh C glycoprotein deletion alters basal and Acidosis-stimulated renal ammonia excretion.
- CXCR4/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus.
- Basolateral expression of the ammonia transporter family member Rh C glycoprotein in the mouse Kidney.
- HNF-1beta regulates transcription of the PKD modifier gene Kif12.
- Triptolide reduces cystogenesis in a model of ADPKD.
- Impaired sodium excretion and increased blood pressure in mice With targeted deletion of renal epithelial insulin receptor.
- Kidney cysts, pancreatic cysts, and biliary disease in a mouse model of autosomal recessive polycystic Kidney disease.
- Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.
- Cyst formation and activation of the extracellular regulated kinase pathway after Kidney specific inactivation of Pkd1.
- Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic Kidneys.
- Multiple Renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.
- Mutations of HNF-1beta inhibit epithelial morphogenesis through dysregulation of SOCS-3.
- Renal and bone marrow cells fuse after Renal ischemic injury.
- Gastrointestinal amyloidosis associated With transthyretin Phe64Ser mutation.
- The role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells.
- Targeted inactivation of fh1 causes proliferative Renal cyst development and activation of the hypoxia pathway.
- Proteolytic cleavage and nuclear translocation of fibrocystin is regulated by intracellular Ca2+ and activation of protein kinase C.
- Expression of the basolateral Na-K-Cl cotransporter during mouse nephrogenesis and embryonic development.
- Roles of HNF-1beta in Kidney development and congenital cystic diseases.
- Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic Kidney.
- Elucidating the function of primary cilia by conditional gene inactivation.
- Overview: nonmammalian organisms for studies of Kidney development and disease.
- Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and Renal cystogenesis.
- Cystic Renal neoplasia following conditional inactivation of apc in mouse Renal tubular epithelium.
- Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus.
- Kidney-specific gene targeting.
- Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces Renal cysts in mice.
- A transcriptional network in polycystic Kidney disease.
- Loss of NFAT5 results in Renal atrophy and lack of tonicity-responsive gene expression.
- Searching for stem/progenitor cells in the adult mouse Kidney.
- Following the expression of a Kidney-specific gene from early development to adulthood.
- Hematopoietic stem cells contribute to the regeneration of Renal tubules after Renal ischemia-reperfusion injury in mice.
- Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic Kidney disease.
- Regulation of Kidney-specific Ksp-cadherin gene promoter by hepatocyte nuclear factor-1beta.
- Genetics and pathogenesis of polycystic Kidney disease.
- Epithelial-specific Cre/lox recombination in the developing Kidney and genitourinary tract.
- A minimal Ksp-cadherin promoter linked to a green fluorescent protein reporter gene exhibits tissue-specific expression in the developing Kidney and genitourinary tract.
- Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in downregulation of p27(kip1) expression during nephrogenesis, glomerular abnormalities, ...
Schools
David Geffen School Of Medicine At UCLA University Of California Los Angeles
University Of California Davis
Yale University
Procedures Preformed
- Hemodialysis
- Peritoneal Dialysis
Conditions Treated
- Acidosis
- Acute Kidney Failure
- Chronic Kidney Diseases
- Diabetes With Renal Manifestations
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Doctors Specialties
- Nephrology
Accepted Insurances
Awards
- Elected Member
- Fellow (ASNF)
Education
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Yale University School of Medicine -
University of California Davis -
David Geffen School of Medicine at UCLA
Hospital
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University of Minnesota Medical Center, Fairview
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1225007792 |
| Last Name Of The Provider | IGARASHI |
| First Name Of The Provider | PETER |
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