Professor, Anesthesiology and Critical Care, Perelman School of Medicine
Anesthesiology
Dr. Roderic G. Eckenhoff, MD
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Roderic Eckenhoff practices Anesthesiology. He studied medicine at Northwestern University Feinberg School of Medicine. Northwestern University Feinberg School of Medicine is ranked 19 in research and 29 in primary care medicine Roderic G. Eckenhoff, MD is a published MD. He published 100 publications, including: 'Do specific or nonspecific interactions with proteins underlie inhalational anesthetic action?' Roderic G. Eckenhoff, MD is registered with Medicare and accepts Medicare payments.
Publications
- Mechanistic Insights into the Modulation of Voltage-Gated Ion Channels by Inhalational Anesthetics.
- Potential Adverse Effects of Anesthesia in Children.
- Role for the Propofol Hydroxyl in Anesthetic Protein Target Molecular Recognition.
- Forward to the past.
- Discovery of a novel general anesthetic chemotype using high-throughput screening.
- Sites and functional consequence of VDAC-alkylphenol anesthetic interactions.
- Modulation of a voltage-gated Na+ channel by sevoflurane involves multiple sites and distinct mechanisms.
- Mechanisms revealed through general anesthetic photolabeling.
- Photoaffinity Labeling the Propofol Binding Site in GLIC.
- Anesthesia, surgery, illness and Alzheimer's disease.
- Propofol Shares the Binding Site with Isoflurane and Sevoflurane on Leukocyte Function-Associated Antigen-1.
- Using the problem-based learning discussion (PBLD) to facilitate research.
- Direct modulation of microtubule stability contributes to anthracene general anesthesia.
- Identification of propofol binding sites in a nicotinic acetylcholine receptor with a photoreactive propofol analog.
- Modulation of murine Alzheimer pathogenesis and behavior by surgery.
- Differential general anesthetic effects on microglial cytokine expression.
- In Vivo Activation of Azi-propofol Prolongs Anesthesia and Reveals Synaptic Targets.
- A novel fluorescent general anesthetic enables imaging of sites of action in vivo.
- Ferritin couples iron and fatty acid metabolism.
- General Anesthetics Predicted to Block the GLIC Pore with Micromolar Affinity.
- Postoperative cognitive decline: where art tau?
- NMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptor.
- Human Alzheimer and Inflammation Biomarkers after Anesthesia and Surgery.
- Anesthesia in presymptomatic Alzheimer's disease: a study using the triple-transgenic mouse model.
- Anesthetic modulation of neuroinflammation in Alzheimer's disease.
- m-Azipropofol (AziPm) a photoactive analogue of the intravenous general anesthetic propofol.
- Multiple binding sites for the general anesthetic isoflurane identified in the nicotinic acetylcholine receptor transmembrane domain.
- Anesthetic-induced neurodegeneration mediated via inositol 1,4,5-trisphosphate receptors.
- Azi-isoflurane, a Photolabel Analog of the Commonly Used Inhaled General Anesthetic Isoflurane.
- Anesthesia and the old brain.
- Inhaled anesthetic potency in aged Alzheimer mice.
- Inhalational anesthetic photolabeling.
- A conserved behavioral state barrier impedes transitions between anesthetic-induced unconsciousness and wakefulness: evidence for neural inertia.
- A unitary anesthetic binding site at high resolution.
- Identification of a fluorescent general anesthetic, 1-aminoanthracene.
- A high-throughput approach for identification of novel general anesthetics.
- Why can all of biology be anesthetized?
- Does it add up?
- Brain and behavior changes in 12-month-old Tg2576 and nontransgenic mice exposed to anesthetics.
- The common inhalational anesthetic isoflurane induces apoptosis via activation of inositol 1,4,5-trisphosphate receptors.
- A presenilin-1 mutation renders neurons vulnerable to isoflurane toxicity.
- Thermodynamics of xenon binding to cryptophane in water and human plasma.
- Limitations of microarray studies.
- Risk factors for venous gas emboli after decompression from prolonged hyperbaric exposures.
- Halothane binding proteome in human brain cortex.
- Partitioning of anesthetics into a lipid bilayer and their interaction with membrane-bound peptide bundles.
- Image not living up to goal.
- Photoactive analogues of the haloether anesthetics provide high-resolution features from low-affinity interactions.
- Interactions of volatile anesthetics with neurodegenerative-disease-associated proteins.
- Rat brain DNA transcript profile of halothane and isoflurane exposure.
- Anesthetic potency of two novel synthetic polyhydric alkanols longer than the n-alkanol cutoff: evidence for a bilayer-mediated mechanism of anesthesia?
- Weak polar interactions confer albumin binding site selectivity for haloether anesthetics.
- Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein.
- Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity.
- Inhalational anesthetic-binding proteins in rat neuronal membranes.
- Independent cerebral vasoconstrictive effects of hyperoxia and accompanying arterial hypocapnia at 1 ATA.
- Identification of nicotinic acetylcholine receptor amino acids photolabeled by the volatile anesthetic halothane.
- The role of electrostatic interactions in human serum albumin binding and stabilization by halothane.
- Chromatographic approach for determining the relative membrane permeability of drugs.
- G protein-coupled receptors as direct targets of inhaled anesthetics.
- Halogenated diazirines as photolabel mimics of the inhaled haloalkane anesthetics.
- Low-affinity analytical chromatography for measuring inhaled anesthetic binding to isolated proteins.
- Multiple specific binding targets for inhaled anesthetics in the mammalian brain.
- Stereoselectivity of isoflurane in adhesion molecule leukocyte function-associated antigen-1.
- Anesthetic drug development: Novel drugs and new approaches.
- Volatile Anesthetics, Not Intravenous Anesthetic Propofol Bind to and Attenuate the Activation of Platelet Receptor Integrin ?IIb?3.
- Differential effects of volatile and intravenous anesthetics on the activity of human TASK-1.
- Anesthetic stabilization of protein intermediates: myoglobin and halothane.
- Determination of the hydrophobicity of local anesthetic agents.
- Predictability of weak binding from X-ray crystallography: inhaled anesthetics and myoglobin.
- Cooperative binding of inhaled anesthetics and ATP to firefly luciferase.
- Halothane binding to a G protein coupled receptor in retinal membranes by photoaffinity labeling.
- Inhaled anesthetic binding sites in human serum albumin.
- Gamma-aminobutyric acid enhancement of halothane binding in rat cerebellum.
- General anesthetic binding to gramicidin A: the structural requirements.
- A designed four-alpha-helix bundle that binds the volatile general anesthetic halothane with high affinity.
- On the relevance of "clinically relevant concentrations" of inhaled anesthetics in in vitro experiments.
- Steric hindrance is not required for n-alkanol cutoff in soluble proteins.
- Halothane, an inhalational anesthetic agent, increases folding stability of serum albumin.
- Volatile anesthetics alter protein stability.
- Do specific or nonspecific interactions with proteins underlie inhalational anesthetic action?
- A noble approach to mechanisms.
- Differential halothane binding and effects on serum albumin and myoglobin.
- Quantitative autoradiography of halothane binding in rat brain.
- Molecular interactions between inhaled anesthetics and proteins.
- Heterogeneous halothane binding in the SR Ca2+-ATPase.
- Amino acid resolution of halothane binding sites in serum albumin.
- Minimum structural requirement for an inhalational anesthetic binding site on a protein target.
- An inhalational anesthetic binding domain in the nicotinic acetylcholine receptor.
- Inhibition of dopamine transport in rat brain synaptosomes by volatile anesthetics.
- Inhalation anaesthetic competition at high-affinity cocaine binding sites in rat brain synaptosomes.
- Absence of pressure antagonism of ethanol narcosis in C. elegans.
- Halothane binding to soluble proteins determined by photoaffinity labeling.
- Binding of halothane to serum albumin demonstrated using tryptophan fluorescence.
- Tests of anesthesia relevance.
- Violence in America. Effective solutions.
- Elemental composition of lamellar bodies from fetal and adult human lung.
- Latency in onset of decompression sickness on direct ascent from air saturation.
- Hematologic and hemostatic changes with repetitive air diving.
Schools
Northwestern University The Feinberg School Of Medicine
Evanston Hospital
Hospital Of The University Of Pennsylvania
Penn Muscle Institute University Penn
Doctors Specialties
- Anesthesiology
Accepted Insurances
Education
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McGaw Medical Center of Northwestern University -
Northwestern University Feinberg School of Medicine
Hospital
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Hospital of the University of Pennsylvania
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1497791446 |
| Last Name Of The Provider | ECKENHOFF |
| First Name Of The Provider | RODERIC |
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