Professor, Internal Medicine, University of Texas Southwestern Medical Center, Southwestern Medical School
Endocrinology
Dr. Roger H. Unger, MD
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Roger H. Unger, MD works in the field of Endocrinology. He graduated from Columbia University College of Physicians & Surgeons. Columbia University College of Physicians & Surgeons is a top medical university. Columbia University College of Physicians & Surgeons has a rank of 8 in research and a 52 in primary care He received awards:"Whos Who in Medicine and Healthcare" and "Elected Member". Doctor Roger H. Unger, MD is a published physician. He published 102 publications, including: 'The effects of acute and chronic insulin administration on plasma IRG levels in human diabetes.'
Publications
- MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival and Intra-Insular Crosstalk.
- Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway.
- A New Biology of Diabetes Revealed by Leptin.
- Alveolar-capillary adaptation to chronic hypoxia in the fatty lung.
- Noninvasive assessment of alveolar microvascular recruitment in conscious non-sedated rats.
- Dichotomous roles of leptin and adiponectin as enforcers against lipotoxicity during feast and famine.
- Role of fibroblast growth factor 21 in biology of glucagon.
- Iatrogenic hyperinsulinemia in type 1 diabetes: Its effect on atherogenic risk markers.
- Pancreatic steatosis and its relationship to β-cell dysfunction in humans: racial and ethnic variations.
- Metabolic manifestations of insulin deficiency do not occur without glucagon action.
- Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover.
- Glucagon Responses of Isolated ? Cells to Glucose, Insulin, Somatostatin, and Leptin.
- Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice.
- Fatty diabetic lung: functional impairment in a model of metabolic syndrome.
- Paracrinology of islets and the paracrinopathy of diabetes.
- Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity.
- Leptin therapy in insulin-deficient type I diabetes.
- Fatty diabetic lung: altered alveolar structure and surfactant protein expression.
- Diabetes and apoptosis: lipotoxicity.
- Noninvasive quantification of pancreatic fat in humans.
- Making insulin-deficient type 1 diabetic rodents thrive without insulin.
- Noninvasive tracking of gene expression by reporter transgene imaging.
- Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome.
- Reinventing type 2 diabetes: pathogenesis, treatment, and prevention.
- Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America.
- Metabolic mechanisms of failure of intraportally transplanted pancreatic beta-cells in rats: role of lipotoxicity and prevention by leptin.
- Combined leptin actions on adipose tissue and hypothalamus are required to deplete adipocyte fat in lean rats: implications for obesity treatment.
- Alpha-lipoic acid prevents lipotoxic cardiomyopathy in acyl CoA-synthase transgenic mice.
- Movin' on up: adipocytes become regulators of nutrient homeostasis.
- Klotho-induced insulin resistance: a blessing in disguise?
- Fat storage in adipocytes requires inactivation of leptin's paracrine activity: implications for treatment of human obesity.
- Hyperleptinemia: protecting the heart from lipid overload.
- Role of PP2C in cardiac lipid accumulation in obese rodents and its prevention by troglitazone.
- Demonstration of reverse fatty acid transport from rat cardiomyocytes.
- Independence of hyperleptinemia-induced fat disappearance from thyroid hormone.
- Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice.
- Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue.
- Hepatic insig-1 or -2 overexpression reduces lipogenesis in obese Zucker diabetic fatty rats and in fasted/refed normal rats.
- The hyperleptinemia of obesity-regulator of caloric surpluses.
- Rapid transformation of white adipocytes into fat-oxidizing machines.
- Increased expression and activity of 11beta-HSD-1 in diabetic islets and prevention with troglitazone.
- Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome.
- Lipid overload and overflow: metabolic trauma and the metabolic syndrome.
- Insig-1 "brakes" lipogenesis in adipocytes and inhibits differentiation of preadipocytes.
- The physiology of cellular liporegulation.
- Effects of leptin, troglitazone, and dietary fat on stearoyl CoA desaturase.
- Gene expression profile of rat adipose tissue at the onset of high-fat-diet obesity.
- Lipotoxic diseases.
- The molecular forms of immunoreactive glucagon secreted by the isolated, perfused dog pancreas.
- Age-dependence of lipid parameters in the general population and vegetarians.
- Muscle capillary basement membrane width in normal, diabetic and prediabetic patients.
- Childhood obesity. Medical and familial correlates and age of onset.
- [Effects of gut hormone on insulin and glucagon secretion].
- Effect of acute hyperkalemia on plasma insulin and glucagon.
- Characterization of immunoreactive components of insulin and somatostatin in canine pancreatic juice.
- Active hepatic glycogen synthesis from gluconeogenic precursors despite high tissue levels of fructose 2,6-bisphosphate.
- A glucagon-secreting alpha-cell carcinoma of the pancreas.
- Further electron microscopic studies of diabetic microangiopathy.
- Gastric function and obesity: gastric emptying, gastric acid secretion, and plasma pepsinogen.
- Nocturnal hypoglycemia in aggressively controlled diabetes.
- Possible role of insulin-stimulating hormones in disturbances of nutrient tolerance.
- The organ of Langerhans in new perspective.
- Lack of a "big plasma glucagon" response during arginine stimulation of glucagon secretion.
- Effect of prostaglandin E2 upon release of pancreatic somatostatin-like immunoreactivity.
- Morphine and beta-endorphin influence the secretion of the endocrine pancreas.
- The relationship between the mechanism of action of the sulfonylureas and the secretion of insulin into the portal circulation.
- Release of somatostatin-like immunoreactivity from the lower gut.
- Relation between glycaemic control, hyperinsulinaemia and plasma concentrations of soluble adhesion molecules in patients with impaired glucose tolerance or Type II di...
- Immunoreactive somatostatin levels in plasma of normal and alloxan diabetic dogs.
- Measurements of somatostatin-like immunoreactivity in plasma.
- Somatostatin is decreased in the neurohypophysis of the Brattleboro rat and may play a role in the regulation of vasopressin secretion.
- Tolbutamide-phenformin in ketoacidosis-resistant patients.
- Free somatostatin in the circulation: amounts and molecular sizes of somatostatin-like immunoreactivity in portal, aortic, and vena caval plasma of fasting and meal-st...
- Effect of exogenous and endogenous prostaglandin E upon gastric endocrine function in dogs.
- Evidence for the presence of glucagon-like immunoreactivity (GLI) in the pancreas.
- Plasma somatostatin-like immunoreactivity in depancreatized dogs.
- Properties of somatostatin-like immunoreactive polypeptides in the canine extrahypothalamic brain and stomach.
- Glucagon and diabetes.
- Evidence for an insulin-independent alpha-cell abnormality in human diabetes.
- The effects of glucagon administration to nondiabetics and diabetics.
- Effects of carbohydrate deprivation.
- Insulin glucagon ration.
- Glucagon and diabetes mellitus.
- Feedback inhibition of insulin secretion by insulin: relation to the hyperinsulinemia of obesity.
- Beta-endorphin and the endocrine pancreas. Studies in healthy and diabetic human beings.
- Inhibitory effect of intragastric glucose on gastric acid secretion and gastric emptying of liquids in man. Role of endogenous somatostatin, gastrin, and insulin.
- THE EFFECTS OF COCL-2 ON GLUCAGON LEVELS IN PLASMA AND PANCREAS OF THE RAT.
- Radioimmunoassay of glucagon.
- How pancreatic glucagon can affect health.
- The milieu interieur and the islets of Langerhans.
- Characteristics of tissue IRGs in the dog.
- The effects of acute and chronic insulin administration on plasma IRG levels in human diabetes.
- Hyperglucagonaemia after burns.
- Nonthyroidal control of metabolism after burn injury: possible role of glucagon.
- Glucagon physiology and pathophysiology in the light of new advances.
- [New findings on the mechanisms of secretion of glucagon].
- Response of plasma somatostatin-like immunoreactivity to the administration of alloxan in dogs.
- Effect of bombesin upon plasma somatostatin-like immunoreactivity, insulin and glucagon in normal and chemically sympathectomized dogs.
- Sympathectomy and prostaglandin deficiency do not prevent gastrogenic hyperglycaemia and hyperinsulinaemia.
- Dermorphin: an opioid peptide from amphibian skin which affects endocrine pancreatic function.
- An AlphaScreen Assay for the Discovery of Synthetic Chemical Inhibitors of Glucagon Production.
Schools
Columbia University College of Physicians And Surgeons
Bellevue Hospital Center
Doctors Specialties
- Internal Medicine
- Endocrinology
Accepted Insurances
Awards
- Whos Who in Medicine and Healthcare
- Elected Member
Education
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NYU School of Medicine -
Columbia University College of Physicians & Surgeons
Hospital
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University of Texas Southwestern Medical Center
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