Professor of Anesthesiology and Critical Care Medicine, Professor of Neurology, Johns Hopkins University School of Medicine; Director, Division of Pain Medicine, Department of Anesthesiology and Critical Care Medicine, Director of Pain Research, Departmen

Anesthesiology

Srinivasa Raja works in the field of Anesthesiology. He went to Patna Medical College. He received awards:"America's Top Doctors", "CMS Meaningful Use Stage 1 Certification", "Top Doctors:Baltimore Area", "Top Doctors:Washington-Baltimore" and "Super Doctor". Srinivasa N. Raja, MD is a published doctor. He published 74 publications, including: 'Mas-Related G Protein-Coupled Receptors Offer Potential New Targets for Pain Therapy.' Srinivasa N. Raja, MD accepts Medicare payments and is registered with Medicare.gov.

Publications

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• Activation of Peripheral μ-opioid Receptors by Dermorphin [D-Arg2, Lys4] (1-4) Amide Leads to Modality-preferred Inhibition of Neuropathic Pain.
• Research design considerations for single-dose analgesic clinical trials in acute pain: IMMPACT recommendations.
• An introduction to the biennial review of pain.
• Injury-specific promoters enhance herpes simplex virus-mediated gene therapy for treating neuropathic pain in rodents.
• Electrical stimulation of low-threshold afferent fibers induces a prolonged synaptic depression in lamina II dorsal horn neurons to high-threshold afferent inputs in m...
• Dynamic Pain Phenotypes are Associated with Spinal Cord Stimulation-Induced Reduction in Pain: A Repeated Measures Observational Pilot Study.
• Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis.
• Lenalidomide for Complex Regional Pain Syndrome Type 1: Lack of Efficacy in a Phase II Randomized Study.
• Improved Upper Limits on the Stochastic Gravitational-Wave Background from 2009-2010 LIGO and Virgo Data.
• Electrical Stimulation of Dorsal Root Entry Zone Attenuates Wide-Dynamic-Range Neuronal Activity in Rats.
• A sore spot: Central or peripheral generation of chronic neuropathic spontaneous pain?
• Research designs for proof-of-concept chronic pain clinical trials: IMMPACT recommendations.
• Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice.
• Modulating the delicate glial-neuronal interactions in neuropathic pain: Promises and potential caveats.
• Intrathecal carbenoxolone inhibits neuropathic pain and spinal wide-dynamic range neuronal activity in rats after an L5 spinal nerve injury.
• MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain.
• Temporal changes in MrgC expression after spinal nerve injury.
• Abuse liability measures for use in analgesic clinical trials in patients with pain: IMMPACT recommendations.
• Tolerance to the antiallodynic effects of the peripherally acting opioid loperamide hydrochloride develops in nerve-injured rats.
• Interventional management of neuropathic pain: NeuPSIG recommendations.
• Prevention of chronic postsurgical pain: the ongoing search for the holy grail of anesthesiology.
• Research design considerations for clinical studies of abuse-deterrent opioid analgesics: IMMPACT recommendations.
• Local loperamide injection reduces mechanosensitivity of rat cutaneous, nociceptive C-fibers.
• Considerations for improving assay sensitivity in chronic pain clinical trials: IMMPACT recommendations.
• Testing the Link between Sympathetic Efferent and Sensory Afferent Fibers in Neuropathic Pain.
• Modulating Pain in the Periphery: Gene-Based Therapies to Enhance Peripheral Opioid Analgesia: Bonica Lecture, ASRA 2010.
• Preventing Chronic Pain following Acute Pain: Risk Factors, Preventive Strategies, and their Efficacy.
• TRP Vanilloid 2 Knock-Out Mice Are Susceptible to Perinatal Lethality But Display Normal Thermal and Mechanical Nociception.
• A Peripheral Adrenoceptor-mediated Sympathetic Mechanism Can Transform Stress-induced Analgesia into Hyperalgesia.
• The contribution of sympathetic mechanisms to postamputation phantom and residual limb pain: a pilot study.
• Considerations for extrapolating evidence of acute and chronic pain analgesic efficacy.
• Dynamic temporal and spatial regulation of mu opioid receptor expression in primary afferent neurons following spinal nerve injury.
• Painful sequelae following limb salvage: etiology and management.
• Spinal cord stimulation-induced analgesia: electrical stimulation of dorsal column and dorsal roots attenuates dorsal horn neuronal excitability in neuropathic rats.
• Mas-related G-protein-coupled receptors inhibit pathological pain in mice.
• A role for acid-sensing ion channel 3, but not acid-sensing ion channel 2, in sensing dynamic mechanical stimuli.
• Wide-dynamic-range neurons are heterogeneous in windup responsiveness to changes in stimulus intensity and isoflurane anesthesia level in mice.
• Predicting postoperative pain based on preoperative pain perception: are we doing better than the weatherman?
• Preventing chronic postsurgical pain: how much of a difference makes a difference?
• Treatment considerations for patients with neuropathic pain and other medical comorbidities.
• Recommendations for the pharmacological management of neuropathic pain: an overview and literature update.
• A web-based cross-sectional epidemiological survey of complex regional pain syndrome.
• Morphine versus mexiletine for treatment of postamputation pain: a randomized, placebo-controlled, crossover trial.
• What can we learn from failed neuropathic pain trials?
• An update on the treatment of postherpetic neuralgia.
• Diagnosis and assessment of pain associated with herpes zoster and postherpetic neuralgia.
• Predictors and consequences of multiple persistent postmastectomy pains.
• Lumbar sympathectomy attenuates cold allodynia but not mechanical allodynia and hyperalgesia in rats with spared nerve injury.
• Transdermal fentanyl reduces pain and improves functional activity in neuropathic pain states.
• Pathogenesis, diagnosis, and treatment of lumbar zygapophysial (facet) joint pain.
• Advances in treatment of complex regional pain syndrome: recent insights on a perplexing disease.
• Local administration of norepinephrine in the stump evokes dose-dependent pain in amputees.
• Windup in dorsal horn neurons is modulated by endogenous spinal mu-opioid mechanisms.
• Combination therapy for neuropathic pain--which drugs, which combination, which patients?
• Severing the link between acute and chronic pain: the anesthesiologist's role in preventive medicine.
• Postoperative cognitive function as an outcome of regional anesthesia and analgesia.
• The birth of opioid anesthesia.
• Antiallodynic effects of systemic and intrathecal morphine in the spared nerve injury model of neuropathic pain in rats.
• Nerve injury induces a tonic bilateral mu-opioid receptor-mediated inhibitory effect on mechanical allodynia in mice.
• Analgesic effects of a soy-containing diet in three murine bone cancer pain models.
• Dietary constituents as novel therapies for pain.
• Role of micro-opioid receptors in formalin-induced pain behavior in mice.
• Spinal cord stimulation for complex regional pain syndrome: an evidence-based medicine review of the literature.
• A mouse model of incisional pain.
• Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein.
• Opioids: more to learn, improvements to be made.
• Drug infusions for the diagnosis and treatment of chronic pain.
• Current management of postherpetic neuralgia.
• Optimizing postoperative analgesia: the use of global outcome measures.
• Complex regional pain syndrome I (reflex sympathetic dystrophy).
• Analgesic effects of intravenous lidocaine and morphine on postamputation pain: a randomized double-blind, active placebo-controlled, crossover trial.
• The correlation between dietary soy phytoestrogens and neuropathic pain behavior in rats after partial denervation.
• Mas-Related G Protein-Coupled Receptors Offer Potential New Targets for Pain Therapy.

Schools

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• Patna University Patna Medical College

• Middlesex Genl Hospital

• University of Washington

• University Of Virginia

Doctors Specialties

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• Anesthesiology
• Pain Medicine Anesthesiology

Accepted Insurances

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Awards

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• America's Top Doctors
• CMS Meaningful Use Stage 1 Certification
• Top Doctors:Baltimore Area
• Top Doctors:Washington-Baltimore
• Super Doctor

Education

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• University of Virginia
• University of Washington
• Patna Medical College

Hospital

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• Johns Hopkins Hospital

Drug Facts

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NPI NUMBER		1609813567
NPPES Provider LastName		RAJA
NPPES Provider FirstName		SRINIVASA
NPPES Provider ZIPCode		212870005
NPPES Provider State		MD
Specialty Description		Anesthesiology
Total Claim Count		133.0
Distinct Opioid Count		0.0
Opioid Claim Count		0.0
Percent Opioid Claims		0.0

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Medicare Facts

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National Provider Identifier [NPI]	1609813567
Last Name Of The Provider	RAJA
First Name Of The Provider	SRINIVASA
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