Professor of Urology in Surgery, The Perelman School of Medicine at The University of Pennsylvania The John W. Duckett Endowed Chair in Pediatric Urology at the Children's Hospital of Philadelphia
Urology
Dr. Stephen A. Zderic, MD
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Stephen Zderic works in the field of Urology. He studied medicine at David Geffen School of Medicine at UCLA. David Geffen School of Medicine at UCLA is a top medical university. David Geffen School of Medicine at UCLA is ranked 13 in research and 7 in primary care medicine He over the years received 3 awards: "Whos Who in Medicine and Healthcare", "Super Doctor" and "Fellow (FACS)". Stephen Zderic is also a published MD. He has 101 paper published. The most recent paper is: Surgical management of the nonpalpable testis: the Children's Hospital of Philadelphia experience.
Publications
- Voiding Dysfunction: What Can Radiologists Tell Patients and Pediatric Urologists?
- Mechanical stretch up-regulates proteins involved in Ca2+-sensitization in Urinary bladder smooth muscle hypertrophy.
- Active surveillance of the adolescent with varicocele: predicting semen outcomes from ultrasound.
- Renal parenchymal area and risk of ESRD in boys with posterior urethral valves.
- Comparison of testicular volume differential calculations in adolescents with varicoceles.
- Effects of Rho-kinase inhibition on myosin light chain phosphorylation and obstruction-induced detrusor overactivity.
- Amino acid mutations in the caldesmon C-terminal functional domain increases force generation in bladder smooth muscle.
- Reproducibility and reliability of semen analysis in youths at risk for infertility.
- GATA-6 and NF-?B Activate CPI-17 Gene Transcription and Regulate Ca2+ Sensitization of Smooth Muscle Contraction.
- Comparison of Semen Analyses in Youths with a History of Cryptorchidism or Varicocele.
- SPONTANEOUS AND EVOKED CONTRACTIONS ARE REGULATED BY PKC MEDIATED SIGNALING IN DETRUSOR SMOOTH MUSCLE: INVOLVEMENT OF BK CHANNELS.
- Water avoidance stress results in an altered voiding phenotype in male mice.
- Calcineurin Mediates Bladder Wall Remodeling Secondary to Partial Outlet Obstruction.
- Alterations in the contractile phenotype of the bladder; lessons for understanding physiological and pathological remodeling of smooth muscle.
- Transcriptional repression of Caveolin-1 (CAV1) gene expression by GATA-6 in bladder smooth muscle hypertrophy in mice and human beings.
- Detrusor overactivity is associated with downregulation of large-conductance calcium- and voltage-activated potassium channel protein.
- Alterations in caveolin expression and ultrastructure after bladder smooth muscle hypertrophy.
- Alteration of the PKC-mediated signaling pathway for smooth muscle contraction in obstruction-induced hypertrophy of the Urinary bladder.
- Impact of overactive bladder on the brain: central sequelae of a visceral pathology.
- Intracytoplasmic sperm injection (ICSI) with transmission of a ring(Y) chromosome and ovotesticular disorder of sex development in offspring.
- Deletion of one SERCA2 allele confers protection against bladder wall hypertrophy in a murine model of partial bladder outlet obstruction.
- Partial bladder outlet obstruction selectively abolishes protein kinase C induced contraction of rabbit detrusor smooth muscle.
- Activation of the calcineurin pathway is associated with detrusor decompensation: a potential therapeutic target.
- Partial bladder outlet obstruction induces urethral smooth muscle hypertrophy and decreased force generation.
- Altered expression of thin filament-associated proteins in hypertrophied Urinary bladder smooth muscle.
- Testicular microlithiasis and antisperm antibodies following testicular biopsy in boys with cryptorchidism.
- Increased corpus cavernosum smooth muscle tone associated with partial bladder outlet obstruction is mediated via Rho-kinase.
- Overnight catheter drainage in children with poorly compliant bladders improves post-obstructive diuresis and Urinary incontinence.
- Prenatally detected primary megaureter: a role for extended followup.
- The value of imaging at the time of symptomatic presentation.
- Regional alterations in the expression of smooth muscle myosin isoforms in response to partial bladder outlet obstruction.
- Giant bladder diverticula causing bladder outlet obstruction in children.
- Partial bladder outlet obstruction abolishes the receptor- and G protein-dependent increase in calcium sensitivity in rabbit bladder smooth muscle.
- A male murine model of partial bladder outlet obstruction reveals changes in detrusor morphology, contractility and Myosin isoform expression.
- Renal and adrenal tumors in children.
- Over expression of smooth muscle specific caldesmon by transfection and intermittent agonist induced contraction alters cellular morphology and restores differentiated...
- Persistent Mullerian duct syndrome associated with 47,XXY genotype.
- Decrease in maximal force generation in the neonatal mouse bladder corresponds to shift in myosin heavy chain isoform composition.
- Smooth muscle hypertrophy following partial bladder outlet obstruction is associated with overexpression of non-muscle caldesmon.
- Experience with testis sparing surgery for testicular teratoma.
- Murine in vitro whole bladder model: a method for assessing phenotypic responses to pharmacologic stimuli and hypoxia.
- Obstruction-induced changes in Urinary bladder smooth muscle contractility: a role for Rho kinase.
- Partial bladder outlet obstruction alters Ca2+ sensitivity of force, but not of MLC phosphorylation, in bladder smooth muscle.
- Testis histopathology in boys with cryptorchidism correlates with future fertility potential.
- The fate of Urinary bladder smooth muscle after outlet obstruction--a role for the sarcoplasmic reticulum.
- Murine in vitro whole bladder physiology.
- The ascending testis and the testis Undescended since birth share the same histopathology.
- Generation of a cell line with smooth muscle phenotype from hypertrophied Urinary bladder.
- Enhanced force generation by corpus cavernosum smooth muscle in rabbits with partial bladder outlet obstruction.
- The CHOP experience with cloacal exstrophy and gender reassignment.
- Bilateral pelvi-ureteric junction obstruction in a neonate presenting with sudden anuria.
- Insight on pathogenesis of varicoceles: relationship of varicocele and body mass index.
- Quantifying demographic, urological and behavioral characteristics of children with lower Urinary tract symptoms.
- Cryptorchid testis histopathology in myelomeningocele patients.
- Lipid signaling changes in smooth muscle remodeling associated with partial Urinary bladder outlet obstruction.
- Smooth muscle trans-membrane sarcoglycan complex in partial bladder outlet obstruction.
- Impact of state of arousal and stress neuropeptides on urodynamic function in freely moving rats.
- A second leiomyosarcoma in the Urinary bladder of a child with a history of retinoblastoma 12 years following partial cystectomy.
- The physical characteristics of young males with varicocele.
- Molecular response of the bladder to obstruction.
- Alteration in expression of myosin isoforms in detrusor smooth muscle following bladder outlet obstruction.
- Effect of partial outlet obstruction on rabbit Urinary bladder smooth muscle function.
- Development factors in the contractile response of the rabbit bladder to both autonomic and non-autonomic agents.
- Developmental aspects of bladder contractile function: sensitivity to extracellular calcium.
- Effects of pregnancy on muscarinic receptor density and function in the rabbit Urinary bladder.
- Effect of pregnancy on rabbit Urinary bladder physiology. 1. Effects of extracellular calcium.
- Urological applications of human papillomavirus typing using deoxyribonucleic acid probes for the diagnosis and treatment of genital condyloma.
- Bladder calculi in women after urethrovesical suspension.
- Results of carbon dioxide laser therapy and topical 5-fluorouracil treatment for subclinical condyloma found by magnified penile surface scanning.
- Carbon dioxide laser therapy of subclinical condyloma found by magnified penile surface scanning.
- Transcystoscopic Ureteral dilatation and ureteroscopy.
- Use of injectable fat to obstruct the urethra in rabbits.
- Developmental factors in the contractile response of rabbit Urinary bladder: effect of anoxia and extracellular acidosis.
- The ontogeny of bladder function in the fetal calf.
- Ontogeny of the ryanodine receptor in rabbit Urinary bladder smooth muscle.
- Effect of partial outlet obstruction of the rabbit Urinary bladder on ryanodine binding to microsomal membranes.
- Effect of partial outlet obstruction on the biphasic response to field stimulation at different concentrations of calcium.
- Primary dilated megaureter: long-term followup.
- Developmental aspects of excitation contraction coupling of rabbit bladder smooth muscle.
- Bovine bladder compliance increases with normal fetal development.
- What is the most accurate way to study the active properties of bladder smooth muscle?
- Nonoperative management of blunt pediatric major renal trauma.
- Effect of ryanodine on the contractile response of the normal and hypertrophied rabbit Urinary bladder to field stimulation.
- Developmental aspects of bladder contractile function: evidence for an intracellular calcium pool.
- Developmental aspects of excitation contraction coupling in Urinary bladder smooth muscle.
- The decompensated detrusor I: the effects of bladder outlet obstruction on the use of intracellular calcium stores.
- The decompensated detrusor II: evidence for loss of sarcoplasmic reticulum function after bladder outlet obstruction in the rabbit.
- 10-year experience with prenatal intervention for Hydronephrosis.
- Increased prevalence of Urinary symptoms and voiding dysfunction in Williams syndrome.
- Effect of thapsigargin on the contractile response of the normal and obstructed rabbit Urinary bladder.
- Properties of Ca2(+)-Mg2+ ATP-ase in rabbit bladder muscle and mucosa: effect of Urinary outlet obstruction.
- Brachytherapy for residual intra-renal Wilms' tumor.
- Compliance of the obstructed fetal rabbit bladder.
- Contractile protein changes in Urinary bladder smooth muscle during obstruction-induced hypertrophy.
- Lateral meningocele syndrome: three new patients and review of the literature.
- Skin flap closure by dermal laser soldering: a wound healing model for sutureless hypospadias repair.
- Partial bladder outlet obstruction in the fetal rabbit.
- The operative management of recurrent ureteropelvic junction obstruction.
- Laser soldering technique for sutureless urethral surgery.
- Surgical management of the nonpalpable testis: the Children's Hospital of Philadelphia experience.
Schools
David Geffen School Of Medicine At UCLA University Of California Los Angeles
University Of Pa Health System
Procedures Preformed
- Cystourethroscopy and Transurethral Resection of Bladder Neck
- Destruction or Excision of Vaginal Lesions
- Excision of Testicular Lesion
- Orchiectomy
Conditions Treated
- Hydronephrosis
- Kidney Stones
- Undescended Testicles
- Ureteral Stones
- View All
Doctors Specialties
- Pediatric Urology
- Urology
Accepted Insurances
Awards
- Whos Who in Medicine and Healthcare
- Super Doctor
- Fellow (FACS)
Education
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University of Pennsylvania Health System -
David Geffen School of Medicine at UCLA
Hospital
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Hospital of the University of Pennsylvania
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