Professor, Medicine, Vanderbilt University School of Medicine
Hematology
Dr. Stephen Brandt, MD
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Stephen Brandt is an expert in the field of Hematology. He over the years received 1 awards: "Elected Member". Stephen Brandt is a published MD as well. He has 61 publications published. The latest was: Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems.
Publications
- Measurement of the Top Quark Pair Production Cross Section in Proton-Proton Collisions at sqrt[s]=13  TeV.
- Study of B Meson Production in p+Pb Collisions at sqrt[s_{NN}]=5.02  TeV Using Exclusive Hadronic Decays.
- Requirement for Ssbp2 in Hematopoietic Stem Cell Maintenance and Stress Response.
- A Single Nucleotide Polymorphism in SLC7A5 is Associated with Gastrointestinal Toxicity after High-Dose Melphalan and Autologous Stem Cell Transplantation for Multiple...
- Identification of the homologous beige and Chediak-Higashi syndrome genes.
- Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems.
- Human thymic epithelial cells produce granulocyte and macrophage colony-stimulating factors.
- Glucocorticoid-stimulated increase in chemotactic peptide receptors on differentiating human Myeloid leukemia (HL-60) cells.
- Constitutive production of macrophage colony-stimulating factor by human ovarian and breast cancer cell lines.
- Density heterogeneity of neutrophilic polymorphonuclear leukocytes: gradient fractionation and relationship to chemotactic stimulation.
- Fibrosarcoma cells transduced with the IL-6 gene exhibited reduced tumorigenicity, increased immunogenicity, and decreased metastatic potential.
- Conversion of intravenous insulin infusions to subcutaneously administered insulin glargine in patients with hyperglycemia.
- Inpatient management of hyperglycemia: the Northwestern experience.
- Retroviral-mediated transfer of interleukin-6 into hematopoietic cells of mice results in a syndrome resembling Castleman''s disease.
- Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation.
- Effect of recombinant human granulocyte-macrophage colony-stimulating factor on hematopoietic reconstitution after high-dose chemotherapy and autologous bone marrow tr...
- Identification of mutations in two major mRNA isoforms of the Chediak-Higashi syndrome gene in human and mouse.
- Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1.
- Donor origin of circulating endothelial progenitors after allogeneic bone marrow transplantation.
- TAL1/SCL is expressed in endothelial progenitor cells/angioblasts and defines a dorsal-to-ventral gradient of vasculogenesis.
- Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.
- SSBP2 is an in vivo tumor suppressor and regulator of LDB1 stability.
- Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.
- Valacyclovir for the prevention of cytomegalovirus infection after allogeneic stem cell transplantation: a single institution retrospective cohort analysis.
- Intensified preparative regimens and autologous transplantation in refractory or relapsed intermediate grade non-Hodgkin''s lymphoma.
- RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription.
- Histone deacetylase inhibitors induce the degradation of the t(8;21) fusion oncoprotein.
- Target-dependent effect of phosphorylation on the DNA binding activity of the TAL1/SCL oncoprotein.
- Age and cytogenetics as predictors of event free survival in patients with acute non-lymphocytic Leukemia receiving high dose cytosine arabinoside and daunorubicin as ...
- Limited efficacy of intensified preparative regimens and autologous transplantation as salvage therapy in high grade non-Hodgkin''s lymphoma.
- Is total body irradiation a necessary component of preparative therapy for autologous transplantation in non-Hodgkin''s lymphoma.
- Intensified preparative regimens and allogeneic transplantation in refractory or relapsed intermediate and high grade non-Hodgkin''s lymphoma.
- Mitogen-activated protein kinase mediates erythropoietin-induced phosphorylation of the TAL1/SCL transcription factor in murine proerythroblasts.
- p300 functions as a transcriptional coactivator for the TAL1/SCL oncoprotein.
- Expression of the TAL1/SCL transcription factor in physiological and pathological vascular processes.
- P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL.
- Erythropoietin stimulates transcription of the TAL1/SCL gene and phosphorylation of its protein products.
- The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis.
- mSin3A regulates murine erythroLeukemia cell differentiation through association with the TAL1 (or SCL) transcription factor.
- Spliced isoforms of LIM-domain-binding protein (CLIM/NLI/Ldb) lacking the LIM-interaction domain.
- Recruitment of the SWI/SNF protein Brg1 by a multiprotein complex effects transcriptional repression in murine erythroid progenitors.
- The TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursors.
- Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors.
- Transforming growth-interacting factor (TGIF) regulates proliferation and differentiation of human Myeloid leukemia cells.
- Regulation of LMO2 mRNA and protein expression in erythroid differentiation.
- GATA-1: one TEF customer.
- Histone deacetylase inhibitor romidepsin has differential activity in core binding factor acute Myeloid leukemia.
- Single-stranded DNA-binding proteins regulate the abundance and function of the LIM-homeodomain transcription factor LHX2 in pituitary cells.
- A computational model of quantitative chromatin immunoprecipitation (ChIP) analysis.
- Genomic structure, alternative splicing and expression of TG-interacting factor, in human Myeloid leukemia blasts and cell lines.
- BRCA1 accumulates in the nucleus in response to hypoxia and TRAIL and enhances TRAIL-induced apoptosis in breast cancer cells.
- High-dose chemotherapy followed by autologous stem cell transplantation for relapsed or refractory Hodgkin lymphoma: prognostic features and outcomes.
- Single-stranded DNA-binding proteins regulate the abundance of LIM domain and LIM domain-binding proteins.
- Transcriptional link between blood and bone: the stem cell Leukemia gene and its +19 stem cell enhancer are active in bone cells.
- Translating the histone code into Leukemia.
- Differential gene expression in anaplastic lymphoma kinase-positive and anaplastic lymphoma kinase-negative anaplastic large cell lymphomas.
- Tal1/SCL binding to pericentromeric DNA represses transcription.
- Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentiation.
- Phosphorylation by mitogen-activated protein kinase mediates the hypoxia-induced turnover of the TAL1/SCL transcription factor in endothelial cells.
- New insights into erythropoiesis.
Schools
Emory University
University Va Health Science Center
Duke University
Conditions Treated
- Chronic Myeloid Leukemia (CML)
- Myeloproliferative Disorders
Doctors Specialties
- Hematology
Accepted Insurances
Awards
- Elected Member
Education
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Duke University Hospital -
University of Virginia
Hospital
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Northside Hospital
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