Physician

Internal Medicine

Dr. Steven C. Griffen, MD

Doctor Steven C. Griffen, MD practices Internal Medicine. He attended Medical College of Wisconsin. Medical College of Wisconsin has a rank of 54 in research and a 62 in primary care Steven Griffen is also a published physician. He has 33 paper published. The most recent paper is: A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets.

Publications

Clinical Pharmacokinetics and Pharmacodynamics of Dapagliflozin, a Selective Inhibitor of Sodium-Glucose Co-transporter Type 2.
Characterization of Renal Glucose Reabsorption in Response to Dapagliflozin in Healthy Subjects and Subjects With Type 2 Diabetes.
Effects of sugar-sweetened beverages on plasma acylation stimulating protein, leptin & adiponectin and metabolic parameters.
Effects of rifampin and mefenamic acid on the pharmacokinetics and pharmacodynamics of dapagliflozin.
Loss of coupling between calcium influx, energy consumption and insulin secretion associated with development of hyperglycaemia in the UCD-T2DM rat model of type 2 dia...
Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humans.
Homozygosity mapping places the acrodermatitis enteropathica gene on chromosomal region 8q24.3.
A model for the evolution of polyubiquitin genes from the study of Arabidopsis thaliana ecotypes.
Insulin exerts metabolic and growth-promoting effects by a direct action on the liver in vivo: clarification of the functional significance of the portal vascular link...
Consumption of fructose-sweetened beverages for 10 weeks reduces net fat oxidation and energy expenditure in overweight/obese men and women.
A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets.
Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in h...
A genetic defect in beta-cell gene expression segregates independently from the fa locus in the ZDF rat.
Increased monocytic activity and biomarkers of inflammation in patients with type 1 diabetes.
Lack of Pharmacokinetic Interactions Between Dapagliflozin and Simvastatin, Valsartan, Warfarin, or Digoxin.
Circulating Concentrations of Monocyte Chemoattractant Protein-1, Plasminogen Activator Inhibitor-1, and Soluble Leukocyte Adhesion Molecule-1 in Overweight/Obese Men ...
Metabolic responses to prolonged consumption of glucose- and fructose-sweetened beverages are not associated with postprandial or 24-h glucose and insulin excursions.
Supplementation with EPA or fish oil for 11 months lowers circulating lipids, but does not delay the onset of diabetes in UC Davis-type 2 diabetes mellitus rats.
Chronic administration of the glucagon-like peptide-1 analog, liraglutide, delays the onset of diabetes and lowers triglycerides in UCD-T2DM rats.
Dietary fructose accelerates the development of diabetes in UCD-T2DM rats: amelioration by the antioxidant, alpha-lipoic acid.
Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans.
Development and characterization of a novel rat model of type 2 diabetes mellitus: the UC Davis type 2 diabetes mellitus UCD-T2DM rat.
Twenty-four-hour endocrine and metabolic profiles following consumption of high-fructose corn syrup-, sucrose-, fructose-, and glucose-sweetened beverages with meals.
Consumption of fructose-sweetened beverages for 10 weeks increases postprandial triacylglycerol and apolipoprotein-B concentrations in overweight and obese women.
Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state.
Evidence of increased inflammation and microcirculatory abnormalities in patients with type 1 diabetes and their role in microvascular complications.
Concomitant reduction of low-density lipoprotein-cholesterol and biomarkers of inflammation with low-dose simvastatin therapy in patients with type 1 diabetes.
Administration of Lispro insulin with meals improves glycemic control, increases circulating leptin, and suppresses ghrelin, compared with regular/NPH insulin in femal...
Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formati...
MAP kinases and their roles in pancreatic beta-cells.
Neurogenin3 and hepatic nuclear factor 1 cooperate in activating pancreatic expression of Pax4.
Regulation of insulin gene transcription by ERK1 and ERK2 in pancreatic beta cells.

Schools

Medical College of Wisconsin
University Of Mi Hosps and Health Ctrs
Vet Affairs Med Center

Doctors Specialties

Internal Medicine

Accepted Insurances

Blue Card PPO
Choice Plus POS
Navigate HMO
Navigate POS
Options PPO

Education

University of Michigan Hospitals and Health Centers
Medical College of Wisconsin

Helpful Reviews

Give Anonymous Review

Similar Doctors

	Dr. Pradeep Mohanroy, MD This Doctor is OpenDoctor Recommended.
	Dr. Michael C. Ullery, MD This Doctor is OpenDoctor Recommended.
	Dr. Schonze F. Del Pozo, MD This Doctor is OpenDoctor Recommended.
	Dr. Ricky W. Winardi, MD This Doctor is OpenDoctor Recommended.
	Dr. Sarah E. Turgasen, MD
	Dr. Marshall H. Lee, MD
	Dr. Gregory P. Marelich, MD This Doctor is OpenDoctor Recommended.
	Dr. Scott A. Fujimoto, MD