Professor, Medicine, Loyola University Chicago Stritch School of Medici
Gastroenterology
Dr. Thomas Layden, MD
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Thomas Layden practices Gastroenterology. He attended Loyola University Chicago Stritch School of Medicine. He received 2 awards: "Fellow (FACP)" and "Super Doctor". Thomas Layden is a published physician. He has 101 publications published. The most current publication "Disseminated histoplasmosis after orthotopic liver transplantation."
Publications
- Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the Hepatitis C virus half-life.
- Liver transplantation for propylthiouracil-induced acute hepatic failure.
- Chronic active Hepatitis associated with etretinate therapy.
- Reversal of growth arrest in adolescents with Crohn''s Disease after parenteral alimentation.
- Retroperitoneal mass and elevation of alpha-fetoprotein following lymphadenectomy and adjuvant chemotherapy for nonseminomatous testicular Cancer.
- Pharmacokinetics and safety of tiagabine in subjects with various degrees of hepatic function.
- Peliosis hepatis in a living related liver transplantation donor candidate.
- Disseminated histoplasmosis after orthotopic liver transplantation.
- Dose-dependent acute clearance of Hepatitis C genotype 1 virus with interferon alfa.
- Salvage of a twisted distal splenorenal shunt graft by using metallic endoprosthesis.
- Identification of two gene variants associated with risk of advanced fibrosis in patients with chronic Hepatitis C.
- Ethnic differences in the presentation of chronic Hepatitis C.
- Hepatitis C virus genotype 1a NS5A pretreatment sequence variation and viral kinetics in African American and white patients.
- p53, Ki-67, and serum alpha feto-protein as predictors of hepatocellular carcinoma recurrence in liver transplant patients.
- Modelling how ribavirin improves interferon response rates in Hepatitis C virus infection.
- Hepatic decompensation after gastric bypass surgery for severe obesity.
- RNA interference as a new strategy against viral Hepatitis.
- Liver transplantation for disulfiram-induced fulminant hepatic failure.
- Viral kinetics in Hepatitis C virus: special patient populations.
- Dynamics of alanine aminotransferase during Hepatitis C virus treatment.
- Modulation of the peripheral T-Cell response by CD4 mutants of Hepatitis C virus: transition from a Th1 to a Th2 response.
- Viral dynamics and Response differences in HCV-infected African American and white patients treated with IFN and ribavirin.
- Mathematical modeling of viral kinetics: a tool to understand and optimize therapy.
- Characterizing Hepatitis B stigma in Chinese immigrants.
- Hepatocyte proliferation and Hepatitis C virus kinetics during treatment.
- Pharmacodynamics of PEG-IFN-[alpha]-2a and HCV Response as a function of IL28B polymorphism in HIV/HCV-coinfected patients.
- Very early prediction of Response to HCV treatment with PEG-IFN-alfa-2a and ribavirin in HIV/HCV-coinfected patients.
- Pharmacodynamics of PEG-IFN-alpha-2a in HIV/HCV co-infected patients: implications for treatment outcomes.
- Liver Injury with Features Mimicking Autoimmune Hepatitis following the Use of Black Cohosh.
- Ethnicity and body mass index are associated with Hepatitis C presentation and progression.
- The prevalence and clinical correlates of elevated ALT levels in an urban Chinatown community.
- Modelling Hepatitis C virus kinetics: the relationship between the infected cell loss rate and the final slope of viral decay.
- Hepatitis B virus clearance rate estimates.
- Hepatitis B seroprevalence and Disease characteristics in an urban Chinatown community.
- Our new president--Gail A. Hecht, MD, MS.
- A mathematical model of hepatitis C virus dynamics in patients with high baseline viral loads or advanced liver Disease.
- The histologic spectrum of liver Disease in African-American, non-Hispanic white, and Hispanic obesity surgery patients.
- Does nonalcoholic fatty liver disease predispose patients to hepatocellular carcinoma in the absence of Cirrhosis?
- Diabetes and hepatic oxidative damage are associated with Hepatitis C progression after liver transplantation.
- Immunohistochemical expression of components of the Akt-mTORC1 pathway is associated with hepatocellular carcinoma in patients with chronic liver Disease.
- Ribavirin: is it a mutagen for Hepatitis C virus?
- A 7 gene signature identifies the risk of developing Cirrhosis in patients with chronic hepatitis C.
- Measurement of liver fat content using selective saturation at 3.0 T.
- A novel antiCancer agent ARC antagonizes HIV-1 and HCV.
- Viral kinetics in the treatment of chronic Hepatitis C.
- Effect of obesity on pharmacokinetics and biologic effect of interferon-alpha in Hepatitis C.
- Intestinal distribution of human Na+/H+ exchanger isoforms NHE-1, NHE-2, and NHE-3 mRNA.
- Calcium regulated chloride permeabilities in primary cultures of rabbit colonocytes.
- Rabbit Esophageal cells show regulatory volume decrease: ionic basis and effect of pH.
- Rabbit Esophageal cells possess K+ channels: effect of hyposmotic stress on channel activity.
- Constipation: is it a risk factor for cholesterol Gallstones?
- Gallstones: choosing the right therapy despite vague clinical clues.
- Cyclic AMP- and phorbol ester-regulated Cl- permeabilities in primary cultures of human and rabbit colonocytes.
- The esophageal mucosal resistance: structure and function of an unique gastroIntestinal epithelial barrier.
- Diagnosis of acute Hepatitis E infection utilizing enzyme immunoassay.
- Clinical and histologic predictors of response to interferon-alpha in patients with chronic Hepatitis C viral infection.
- Escherichia coli heat-stable enterotoxin-mediated colonic Cl- secretion is absent in cystic fibrosis.
- Diagnosis and management of fulminant hepatic failure.
- NHE-1 isoform of the Na+/H+ antiport is expressed in the rat and rabbit esophagus.
- Hepatitis C infection in potential recipients with normal liver biochemistry does not preclude renal transplantation.
- Hepatotoxicity following enflurane anesthesia.
- Edwardsiella tarda gastroEnteritis associated with a pet turtle.
- Cholestatic Hepatitis from use of sulfanilamide vaginal cream.
- Inferior vena cava Obstruction complicating amebic liver abscess.
- Emergency transumbilical embolization of bleeding Esophageal varices.
- An evaluation of total parenteral nutrition in the management of inflammatory bowel Disease.
- Endoscopic control of upper gastroIntestinal hemorrhage with a bipolar coagulation device.
- Limitations of 24-hour intraEsophageal pH monitoring in the hospital setting.
- Erythromycin stearate as prokinetic agent in postvagotomy Gastroparesis.
- Esophageal mucosal resistance. A factor in esophagitis.
- Rabbit Esophageal cells possess an Na+,H+ antiport.
- Age-related effects of chronic ethanol intake on vitamin A status in Fisher 344 rats.
- Diarrhea associated with tube feeding: the importance of using objective criteria.
- In vitro formation of retinoic acid from retinal in rat liver.
- In vivo evidence of altered chloride but not potassium secretion in cystic fibrosis rectal mucosa.
- Isolation, characterization, and attachment of rabbit distal colon epithelial cells.
- Epidemiology considerations in peptic ulcer Disease.
- Rabbit esophageal cell cytoplasmic pH regulation: role of Na(+)-H+ antiport and Na(+)-dependent HCO3- transport Systems.
- Scanning electron microscopy of the rat liver. Studies of the effect of taurolithocholate and other models of cholestasis.
- Taurolithocholate-induced cholestasis: taurocholate but not dehydrocholate, reverses cholestasis and bile canalicular membrane injury.
- Plasma trace metals during total parenteral alimentation.
- Bile formation in the rat: the role of the paracellular shunt pathway.
- [Effect of insulin on bile flow and on enzymes of the hepatic plasma membrane].
- Influence of bile acids on bile canalicular membrane morphology and the lobular gradient in canalicular size.
- Percutaneous needle biopsy specimens. Sampling variability in patients with chronic hepatitis and Cirrhosis.
- The paracellular pathway and bile formation.
- The histopathologic progression of vitamin A-induced hepatic injury.
- Effects of chronic choleretic infusions of bile acids on the membrane of the bile canaliculus. A biochemical and morphologic study.
- The effect of thyroid hormone on bile salt-independent bile flow and Na+, K+ -ATPase activity in liver plasma membranes enriched in bile canaliculi.
- Viral kinetics of Hepatitis C: new insights and remaining limitations.
- Risk factors for failure to meet listing requirements in liver transplant candidates with alcoholic Cirrhosis.
- How can mathematics help us understand HCV?
- Hepatitis C viral dynamics.
- The human Na(+)/H(+) exchanger NHE2 gene: genomic organization and promoter characterization.
- Human Intestinal anion exchanger isoforms: expression, distribution, and membrane localization.
- Mechanism(s) of butyrate transport in Caco-2 cells: role of monocarboxylate transporter 1.
- Hepatitis C kinetics: mathematical modeling of viral response to therapy.
- Differences in viral dynamics between genotypes 1 and 2 of Hepatitis C virus.
- The 20th United States-Japan Joint Hepatitis Panel Meeting.
- Principles of interferon induction therapy.
Schools
Loyola University Of ChicagoStritch School Of Medicine
Barnes Jewish Hospital
University of Chicago
Procedures Preformed
- Colonoscopy, Proctosigmoidoscopy, and Sigmoidoscopy
- Endoscopy (Esophagus, Stomach, Small Intestine)
- Liver Biopsy
Conditions Treated
- Abdominal Pain
- Anemia
- Benign Neoplasm of the Digestive System
- Cholecystitis and Gallstones
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Doctors Specialties
- Gastroenterology
Accepted Insurances
Awards
- Fellow (FACP)
- Super Doctor
Education
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University of Chicago -
Washington University - Barnes-Jewish Hospital -
Loyola University Chicago Stritch School of Medicine
Hospital
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University of Illinois Hospital & Health Sciences System
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