Professor of Medicine; Marian A. and Rodney P. Burgenske Chair; Chief, Division of Endocrinology, Diabetes and Metabolism, University of Wisconsin School of Medicine and Public Health
Endocrinology
Dr. Vincent Cryns, MD
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Dr. Vincent Cryns practices Endocrinology. He graduated from Harvard Medical School. Harvard Medical School is a top medical college. Harvard Medical School is ranked 1/12 in Research/PrimaryCare. He over the years received 2 awards: "Best Doctors in America" and "Elected Member". Dr. Vincent Cryns is also published. He has 63 publications published. The lastest publication: "Proteases to die for.' He accepts Medicare payments and is registered with Medicare.gov.
Publications
- Esterase- and pH-responsive poly(β-amino ester)-capped mesoporous silica nanoparticles for drug delivery.
- ERK-regulated αB-crystallin induction by matrix detachment inhibits anoikis and promotes lung metastasis in vivo.
- Methionine Deprivation Induces a Targetable Vulnerability in Triple-negative Breast Cancer Cells by Enhancing TRAIL Receptor-2 Expression.
- NanoFlares for the detection, isolation, and culture of live Tumor cells from human blood.
- pH and Amphiphilic Structure Direct Supramolecular Behavior in Biofunctional Assemblies.
- αB-crystallin: a Novel Regulator of Breast Cancer Metastasis to the Brain.
- Photoexpulsion of surface-grafted ruthenium complexes and subsequent release of cytotoxic cargos to cancer cells from mesoporous silica nanoparticles.
- ?B-Crystallin promotes oncogenic transformation and inhibits caspase activation in cells primed for apoptosis by Rb inactivation.
- Biotargeted nanomedicines for cancer: six tenets before you begin.
- Small pool expression screening: identification of genes involved in cell cycle control, apoptosis, and early development.
- Specific cleavage of alpha-fodrin during Fas- and Tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct...
- Genomic localization of novel candidate tumor suppressor gene loci in human paraThyroid adenomas.
- p53 Abnormalities in human parathyroid carcinoma.
- Loss of the retinoblastoma tumor-suppressor gene in paraThyroid carcinoma.
- The retinoblastoma gene in human pituitary Tumors.
- Frequent loss of chromosome arm 1p DNA in paraThyroid adenomas.
- Specific proteolysis of the kinase protein kinase C-related kinase 2 by caspase-3 during apoptosis. Identification by a novel, small pool expression cloning strategy.
- Caspases as targets for anti-inflammatory and anti-apoptotic drug discovery.
- The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes.
- Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo.
- Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis.
- The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic ma...
- Inhibition of tau polymerization by its carboxy-terminal caspase cleavage fragment.
- Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis.
- The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation.
- Caspase proteolysis of the cohesin component RAD21 promotes apoptosis.
- AntiTumor activity of peptide amphiphile nanofiber-encapsulated camptothecin.
- American journal of cancer research: editorial board (2011).
- Catechol polymers for pH-responsive, targeted drug delivery to cancer cells.
- Enhanced metastasis suppression by targeting TRAIL receptor 2 in a murine model of triple-negative breast cancer.
- Minireview: Basal-like breast cancer: from molecular profiles to targeted therapies.
- Biological evaluation of pH-responsive polymer-caged nanobins for breast cancer therapy.
- A novel nanoparticulate formulation of arsenic trioxide With enhanced therapeutic efficacy in a murine model of breast cancer.
- Induction of cancer cell death by self-assembling nanostructures incorporating a cytotoxic peptide.
- The small heat shock protein HspB2 is a novel anti-apoptotic protein that inhibits apical caspase activation in the extrinsic apoptotic pathway.
- Induction of the small heat shock protein alphaB-crystallin by genotoxic stress is mediated by p53 and p73.
- Regulation of alphaB-crystallin gene expression by the transcription factor Ets1 in breast cancer.
- Aspirin sensitizes cancer cells to TRAIL-induced apoptosis by reducing survivin levels.
- Caspase cleavage of HER-2 releases a Bad-like cell death effector.
- AlphaB-crystallin: a novel marker of invasive basal-like and metaplastic breast carcinomas.
- Triple negative breast carcinoma and the basal phenoType: from expression profiling to clinical practice.
- alphaB-crystallin is a novel predictor of resistance to neoadjuvant chemOtherapy in breast cancer.
- Caspase proteolysis of the integrin beta4 subunit disrupts hemidesmosome assembly, promotes apoptosis, and inhibits cell migration.
- Plakoglobin Deficiency protects keratinocytes from apoptosis.
- Deconstructing the molecular portrait of basal-like breast cancer.
- Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo.
- AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer.
- The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes.
- Synthetic triterpenoids cooperate With tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells.
- The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.
- A tetracycline-regulated adenovirus encoding dominant-negative caspase-9 is regulated in rat brain and protects against neurotoxin-induced cell death in vitro, but not...
- Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest.
- Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's Disease.
- Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis.
- Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's Disease.
- Crucial role of the specificity-determining loop of the integrin beta4 subunit in the binding of cells to laminin-5 and outside-in signal transduction.
- In vitro models of prostate apoptosis: clusterin as an antiapoptotic mediator.
- C-terminal inhibition of tau assembly in vitro and in Alzheimer's Disease.
- Proteases to die for.
- Activation of caspase-2 in apoptosis.
- Molecular cloning by hybrid arrest of translation in Xenopus laevis oocytes. Identification of a cDNA encoding the Type I iodothyronine 5'-deiodinase from rat liver.
- The effect of cigarette smoking on Adrenal cortical hormones.
Schools
Harvard Medical School
Massachusetts General Hospital
Dartmouth Hitchcock Mc
Mass Genl Hospital Harvard
Conditions Treated
- Abnormal Thyroid
- Adrenal Incidentaloma
- Calcium Metabolism Disorders
- Diabetes Type 1
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Doctors Specialties
- Endocrinology
Accepted Insurances
Awards
- Best Doctors in America
- Elected Member
Education
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Massachusetts General Hospital -
Dartmouth-Hitchcock Medical Center -
Harvard Medical School
Hospital
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University of Wisconsin Hospital and Clinics -
William S. Middleton Memorial Veterans Hospital
Drug Facts
| NPI NUMBER | 1639235039 | |
| NPPES Provider LastName | CRYNS | |
| NPPES Provider FirstName | VINCENT | |
| NPPES Provider ZIPCode | 537172656 | |
| NPPES Provider State | WI | |
| Specialty Description | Endocrinology | |
| Total Claim Count | 128.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1639235039 |
| Last Name Of The Provider | CRYNS |
| First Name Of The Provider | VINCENT |
| View All |
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