Professor of Medicine, University Tex Houston
Oncology
Dr. Waun K. Hong, MD
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Dr. Waun K. Hong practices Oncology. He graduated from Yonsei University College of Medicine. He has 5 awards "America's Top Doctors", "Top Doctors:SE Texas", "America's Top Doctors for Cancer", "Fellow (FASCO)" and "Super Doctor". Dr. Waun K. Hong is also a published physician. He has 101 publication published. The most recent publication is: New DNA Methylation Markers and Global DNA Hypomethylation Are Associated with Oral Cancer Development.
Publications
- From Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology.
- New DNA Methylation Markers and Global DNA Hypomethylation Are Associated with Oral Cancer Development.
- Vandetanib and Indwelling Pleural Catheter for Non-Small-Cell Lung Cancer With Recurrent Malignant Pleural Effusion.
- Prediction of survival in resected non-small cell lung Cancer using a protein-expression based risk model: Implications for personalized chemoprevention and therapy.
- Evaluating physician performance in oncology: moneyball becomes impactball.
- Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs.
- Feasibility of image-guided transthoracic core-needle biopsy in the BATTLE Lung trial.
- An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhi...
- Personalizing Lung Cancer Prevention Through a Reverse Migration Strategy.
- Effect of KRAS Oncogene Substitutions on Protein Behavior: Implications for Signaling and Clinical Outcome.
- Dual inhibition of Tumor Energy Pathway by 2-deoxy glucose and metformin Is Effective Against a Broad Spectrum of Preclinical Cancer Models.
- Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung Cancer.
- Phase II Trials of Imatinib Mesylate and Docetaxel in Patients with Metastatic Non-small Cell Lung Cancer and Head and Neck Squamous Cell Carcinoma.
- The BATTLE to Personalize Lung Cancer Prevention through Reverse Migration.
- Evaluation of Difluoromethylornithine for the Chemoprevention of Barrett's Esophagus and Mucosal Dysplasia.
- Immunohistochemical Overexpression of Platelet-Derived Growth Factor Receptor-Beta (PDGFR-?) is Associated With PDGFRB Gene Copy Number Gain in Sarcomatoid Non-Small-C...
- Prevention of Bronchial Hyperplasia by EGFR Pathway Inhibitors in an Organotypic Culture Model.
- Abnormalities of the TITF-1 Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis.
- Genome-Wide Association Study of Survival in Non-Small Cell Lung Cancer Patients Receiving Platinum-Based Chemotherapy.
- Erratum to: Assessing environmental and occupational risk factors for lung Cancer in Mexican-Americans.
- Gene expression signature-based prognostic risk score in gastric Cancer.
- Global assessment of genetic variation influencing response to retinoid chemoprevention in head and neck Cancer patients.
- Validation of a novel statistical model for assessing the synergy of combined-agent Cancer chemoprevention.
- Epidermal growth factor receptor expression and gene copy number in the risk of oral Cancer.
- Phase 2 study of carboplatin, docetaxel, and bevacizumab as frontline treatment for advanced nonsmall-cell lung Cancer.
- Influence of technologic advances on outcomes in patients with unresectable, locally advanced non-small-cell lung Cancer receiving concomitant chemoradiotherapy.
- Biological activity of celecoxib in the bronchial epithelium of current and former smokers.
- Reduced DNA repair capacity for removing tobacco carcinogen-induced DNA adducts contributes to risk of head and neck Cancer but not tumor characteristics.
- Induction chemotherapy and cetuximab for locally advanced squamous cell carcinoma of the head and neck: results from a phase II prospective trial.
- Expression of interleukin-1 receptor-associated kinase-1 in non-small cell Lung carcinoma and preneoplastic lesions.
- Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the Lung.
- Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung Cancer.
- Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral preMalignant lesions.
- DeltaNp63 overexpression, alone and in combination with other biomarkers, predicts the development of oral Cancer in patients with leukoplakia.
- Elevated epithelial insulin-like growth factor expression is a risk factor for lung Cancer development.
- HER family receptor abnormalities in lung Cancer brain metastases and corresponding primary tumors.
- Identification of gene signatures and molecular markers for human lung Cancer prognosis using an in vitro lung carcinogenesis system.
- Novel susceptibility loci for second primary tumors/recurrence in head and neck Cancer patients: large-scale evaluation of genetic variants.
- A phase II study of Lonafarnib (SCH66336) in patients with chemorefractory, advanced squamous cell carcinoma of the head and neck.
- A phase 2 study of cetuximab in combination with docetaxel in chemotherapy-refractory/resistant patients with advanced nonsmall cell lung Cancer.
- Liposomal encapsulation of deguelin: evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced Lung tumorigenesis.
- Algorithmic guided screening of drug combinations of arbitrary size for activity against Cancer cells.
- Targeting heat shock protein 90 overrides the resistance of lung Cancer cells by blocking radiation-induced stabilization of hypoxia-inducible factor-1alpha.
- Randomized trial of 13-cis retinoic acid compared with retinyl palmitate with or without beta-carotene in Oral premalignancy.
- Phase I trial of weekly topotecan and gemcitabine in patients with solid Tumors.
- Dose escalation of gemcitabine is possible with concurrent chest three-dimensional rather than two-dimensional radiotherapy: a phase I trial in patients with stage III...
- Cyclin D1 and Cancer development in laryngeal premalignancy patients.
- A novel derivative of the natural agent deguelin for Cancer chemoprevention and therapy.
- Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung Cancer treated with platinum-based chemotherapy.
- Immunohistochemical expression of basic fibroblast growth factor and fibroblast growth factor receptors 1 and 2 in the pathogenesis of lung Cancer.
- An expanded risk prediction model for lung Cancer.
- Development and validation of a lung Cancer risk prediction model for African-Americans.
- Impact of smoking cessation on global gene expression in the bronchial epithelium of chronic smokers.
- Clinical prevention of recurrence of Colorectal adenomas by the combination of difluoromethylornithine and sulindac: an important milestone.
- Oral epithelium as a surrogate tissue for assessing smoking-induced molecular alterations in the Lungs.
- Podoplanin: a novel marker for oral Cancer risk in patients with oral premalignancy.
- Identification of novel antiangiogenic antiCancer activities of deguelin targeting hypoxia-inducible factor-1 alpha.
- Proliferative changes in the bronchial epithelium of former smokers treated with retinoids.
- Proteomics-based identification of proteins secreted in apical surface fluid of squamous metaplastic human tracheobronchial epithelial cells cultured by three-dimensio...
- Inhibition of c-Src expression and activation in Malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion.
- Structural basis for depletion of heat shock protein 90 client proteins by deguelin.
- A risk model for prediction of lung Cancer.
- Implication of the insulin-like growth factor-IR pathway in the resistance of non-small cell lung Cancer cells to treatment with gefitinib.
- Nuclear factor-kappaB (NF-kappaB) is frequently expressed in lung Cancer and preneoplastic lesions.
- Identification and validation of differences in protein levels in normal, premalignant, and malignant Lung cells and tissues using high-throughput Western Array and im...
- Joint effect of mutagen sensitivity and insulin-like growth factors in predicting the risk of developing secondary primary Tumors and tumor recurrence in patients with...
- Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlo...
- Involvement of mitochondrial and Akt signaling pathways in augmented apoptosis induced by a combination of low doses of celecoxib and N-(4-hydroxyphenyl) retinamide in...
- Polymorphisms of FAS and FAS ligand genes involved in the death pathway and risk and progression of squamous cell carcinoma of the head and neck.
- Evaluation of glutathione S-transferase polymorphisms and mutagen sensitivity as risk factors for the development of second primary Tumors in patients previously diagn...
- Smoking affects treatment outcome in patients with advanced nonsmall cell lung Cancer.
- Fenretinide activity in retinoid-resistant Oral leukoplakia.
- Randomized phase III trial of low-dose isotretinoin for prevention of second primary tumors in stage I and II head and neck Cancer patients.
- Clinicopathologic characteristics of the EGFR gene mutation in non-small cell lung Cancer.
- Association between glutathione S-transferase pi polymorphisms and survival in patients with advanced nonsmall cell Lung carcinoma.
- Identification of insulin-like growth factor binding protein-3 as a farnesyl transferase inhibitor SCH66336-induced negative regulator of angiogenesis in head and neck...
- Phase II study of pemetrexed in combination with carboplatin in the first-line treatment of advanced nonsmall cell lung Cancer.
- The evolution of treatment outcomes for resected stage IIIA non-small cell lung Cancer over 16 years at a single institution.
- Phenotypic diversity of the Lung vasculature in experimental models of metastases.
- Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced Lung tumorigenesis.
- A phase I/II study of neoadjuvant chemotherapy followed by radiation with boost chemotherapy for advanced T-stage nasopharyngeal carcinoma.
- Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyltransferase inhibitor SCH66336 in human aerodigestive tract Cancer.
- EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung Cancer patients.
- Phase II multicenter study of the epidermal growth factor receptor antibody cetuximab and cisplatin for recurrent and refractory squamous cell carcinoma of the head an...
- Response of non-small cell lung Cancer cells to the inhibitors of phosphatidylinositol 3-kinase/Akt- and MAPK kinase 4/c-Jun NH2-terminal kinase pathways: an effective...
- Effects of 9-cis-retinoic acid on the insulin-like growth factor axis in former smokers.
- Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis.
- Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with Malignant pleural mesotheli...
- Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor ...
- An apple a day...does it really keep the doctor away? The current state of Cancer chemoprevention.
- Phase 2 bioadjuvant study of interferon alfa-2a, isotretinoin, and vitamin E in locally advanced squamous cell carcinoma of the head and neck: long-term follow-up.
- Enhanced growth inhibition and apoptosis induction in NSCLC cell lines by combination of celecoxib and 4HPR at clinically relevant concentrations.
- 9-cis-retinoic acid treatment increases serum concentrations of alpha-tocopherol in former smokers.
- Loss of E-cadherin and p27 expression is associated with head and neck squamous tumorigenesis.
- Oral Cancer prevention and the evolution of molecular-targeted drug development.
- Results of a phase II double-blinded randomized clinical trial of difluoromethylornithine for cervical intraepithelial neoplasia grades 2 to 3.
- Longitudinal study of smoking patterns in relation to the development of smoking-related secondary primary Tumors in patients with upper aerodigestive tract malignancies.
- Thymidylate synthase 5'- and 3'-untranslated region polymorphisms associated with risk and progression of squamous cell carcinoma of the head and neck.
- Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung Cancer cells.
- Prognostic factors in resected stage I non-small-cell lung Cancer: a multivariate analysis of six molecular markers.
Schools
Yonsei University College of Medicine
Bronx Lebanon Hospital
Boston Va Hospital
Sloan Kettering Cancer Center
Procedures Preformed
- Thoracentesis
Conditions Treated
- Adrenal Gland Cancer
- Anemia
- Breast Cancer
- Colorectal Cancer
- View All
Doctors Specialties
- Medical Oncology
- Oncology
Accepted Insurances
Awards
- America's Top Doctors
- Top Doctors:SE Texas
- America's Top Doctors for Cancer
- Fellow (FASCO)
- Super Doctor
Education
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Memorial Sloan-Kettering Cancer Center -
Bronx-Lebanon Hospital Center -
Yonsei University College of Medicine
Hospital
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University of Texas M.D. Anderson Cancer Center -
Baylor St. Luke's Medical Center
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