Professor, Anesthesiology and Critical Care, Perelman School of Medicine
Anesthesiology
Dr. William A. Kofke, MD
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William A. Kofke practices Anesthesiology. He went to medical school at University of Pittsburgh School of Medicine. William Kofke is a published doctor. He published 91 publications, including: 'Correlation of transcranial Doppler sonography mean flow velocity with cerebral blood flow in patients with intracranial pathology.' He is registered with Medicare.
Publications
- 2013 Meeting Report: Society for Neuroscience in Anesthesiology and Critical Care.
- Alternative BIS Montage Positions: Caution Still Warranted.
- Much ado about checklists: who says I need them and who moved my cheese?
- Brief report: a comparison of clinical and research practices in measuring cerebral perfusion pressure: a literature review and practitioner survey.
- Response of Brain Oxygen to Therapy Correlates with Long-Term Outcome After Subarachnoid Hemorrhage.
- Revisiting Gastric Decompression Tube Insertion After Endonasal Neurosurgery: Blamed if You do, Blamed if You Do Not.
- An Alternative Position for the BIS-Vista Montage in Frontal Approach Neurosurgical Cases.
- Striatal extracellular dopamine levels are not increased by hyperglycemic exacerbation of ischemic brain damage in rats.
- Transcranial Doppler ultrasonography with induction of anesthesia for neurosurgery.
- Substantia nigra damage after fluorothyl-induced seizures in rats worsens after post-seizure recovery: no exacerbation with hyperglycaemia.
- Middle cerebral artery blood flow velocity and stable xenon-enhanced computed tomographic blood flow during balloon test occlusion of the internal carotid artery.
- The Anesthesiology Discussion Group: development of a new method of communication between anesthesiologists.
- Cesarean section following ruptured cerebral aneurysm and neuroresuscitation.
- Prolonged low flow isoflurane anesthesia for status epilepticus.
- Comparison of isoflurane, halothane, and nitrous oxide in status epilepticus.
- The occurrence of obstructive sleep apnea in a recovery room patient.
- Continuous hypopharyngeal pH during anesthesia via mask.
- Comparison of the effects of volatile anesthetics on brain glucose metabolism in rats.
- Combined carotid endarterectomy, coronary revascularization, and hypernephroma excision with hypothermic circulatory arrest.
- Neuronal lesions in mercaptopropionic acid-induced status epilepticus.
- Venovenous perfusion of adults and children with severe acute respiratory distress syndrome. The Pennsylvania State University experience from 1982-1987.
- Isoflurane for refractory status epilepticus: a clinical series.
- Substantia nigra lesions in mercaptopropionic acid induced status epilepticus: a light and electron microscopic study.
- Induction of thiopental anesthesia without tracheal intubation in a patient with hiatal hernia: use of esophageal pH monitoring.
- Comparison of the effects of volatile anesthetics in varying concentrations on brain energy metabolism with brain ischemia in rats.
- Alfentanil-induced hypermetabolism, seizure, and histopathology in rat brain.
- Rat muscle 5''-adenylic acid aminohydrolase. I. Purification and subunit structure.
- Studies on the pathogenesis of ischemic brain damage and the mechanism of its amelioration by thiopental.
- Brain blood flow and metabolism after global ischemia and post-insult thiopental therapy in monkeys.
- Transcranial Doppler ultrasonography with induction of anesthesia and neuromuscular blockade in surgical patients.
- Acute care crisis simulation for jury education.
- Phenytoin, midazolam, and naloxone protect against fentanyl-induced brain damage in rats.
- Opioid neurotoxicity: role of neurotransmitter systems.
- The value of acute care simulation.
- Anaesthetic complications of acromegaly.
- Opioid neurotoxicity: fentanyl-induced exacerbation of cerebral ischemia in rats.
- Correlation of transcranial Doppler sonography mean flow velocity with cerebral blood flow in patients with intracranial pathology.
- Anesthetic implications of epilepsy, status epilepticus, and epilepsy surgery.
- Regional cerebral blood flow after subarachnoid hemorrhage (SAH) in the rat.
- Electrographic tachyphylaxis to etomidate and ketamine used for refractory status epilepticus controlled with isoflurane.
- Transcranial Doppler ultrasonography in neurosurgery: effects of intracranial tumour on right middle cerebral artery flow velocity during induction of anaesthesia.
- Opioid neurotoxicity: fentanyl dose-response effects in rats.
- Monitoring for cerebrovascular surgery.
- Making clinical decisions based on animal research data: pro.
- Opioid neurotoxicity: neuropathologic effects in rats of different fentanyl congeners and the effects of hexamethonium-induced normotension.
- Suspended animation for delayed resuscitation.
- Comparison of extracellular dopamine concentration in awake unstressed and postsurgical nitrous oxide sedated rats.
- Increased intracranial pressure in head trauma patients given fentanyl or sufentanil.
- Mannitol: potential for rebound intracranial hypertension?
- Anesthetic care during thiopental tests to evaluate epileptic patients for surgical therapy.
- Effect of anesthetics on neuropathologic sequelae of status epilepticus in rats.
- Glucose utilization during alfentanil-induced seizures in rats.
- Effect of mannitol and hypertonic saline on cerebral oxygenation in patients with severe traumatic brain injury and refractory intracranial hypertension.
- Viable oxygenation with cannula-over-needle cricothyrotomy for asphyxial airway occlusion.
- On a not-dead horse: CPP deserves more respect.
- Detection of cerebral compromise with multimodality monitoring in patients with subarachnoid hemorrhage.
- Brain hypoxia is associated with short-term outcome after severe traumatic brain injury independent of intracranial hypertension and low cerebral perfusion pressure.
- So you think you can safely extubate your patient?
- Potential non-hypoxic/ischemic causes of increased cerebral interstitial fluid lactate/pyruvate ratio: a review of available literature.
- Portable head CT scan and its effect on intracranial pressure, cerebral perfusion pressure, and brain oxygen.
- Phenylephrine infusion prevents impairment of ATP- and calcium-sensitive potassium channel-mediated cerebrovasodilation after brain injury in female, but aggravates im...
- Acute lung injury is an independent risk factor for brain hypoxia after severe traumatic brain injury.
- Impaired cerebral blood flow autoregulation during posttraumatic arterial hypotension after fluid percussion brain injury is prevented by phenylephrine in female but e...
- Successful management of refractory intracranial hypertension from acute hyperammonemic encephalopathy in a woman with ornithine transcarbamylase deficiency.
- Anesthetic management of the patient with epilepsy or prior seizures.
- Brain tissue oxygen-directed management and outcome in patients with severe traumatic brain injury.
- Patient transport and brain oxygen in comatose patients.
- SNP improves cerebral hemodynamics during normotension but fails to prevent sex dependent impaired cerebral autoregulation during hypotension after brain injury.
- Adrenomedullin prevents sex-dependent impairment of autoregulation during hypotension after piglet brain injury through inhibition of ERK MAPK upregulation.
- Incrementally applied multifaceted therapeutic bundles in neuroprotection clinical trials...time for change.
- Disclosure of industry relationships by anesthesiologists: is the conflict of interest resolved?
- Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults.
- Hemoglobin concentration and cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage.
- Induced normothermia attenuates cerebral metabolic distress in patients with aneurysmal subarachnoid hemorrhage and refractory Fever.
- Brain oxygen tension and outcome in patients with aneurysmal subarachnoid hemorrhage.
- Monitoring and intraoperative management of elevated intracranial pressure and decompressive craniectomy.
- Remifentanil-induced cerebral blood flow effects in normal humans: dose and ApoE genotype.
- Nontherapeutic quality improvement: The conflict of organizational ethics and societal rule of law.
- S-100 and NSE changes after cardiac surgery: evaluation of multiple single nucleotide polymorphisms.
- Customized anesthetic preservation of ictal threshold in electroconvulsive therapy: role of adjunctive remifentanil with etomidate.
- Highlights from the 2004 Annual Meeting of the American Society of Anesthesiologists (ASA).
- A retrospective comparison of remifentanil versus methohexital for anesthesia in electroconvulsive therapy.
- The effect of apolipoprotein E genotype on neuron specific enolase and S-100beta levels after cardiac surgery.
- Human serum albumin.
- Second annual meeting of the Neurocritical Care Society: San Diego, California February 7-8, 2004.
- Research ethics and law of healthcare system quality improvement: the conflict of cost containment and quality.
- Toxicity of compound A to C6 rat glioma cells.
- Primarily generalized seizures are more effective than partial seizures in arousing patients from sleep.
- The neuropathologic effects in rats and neurometabolic effects in humans of large-dose remifentanil.
- Evaluation of the thiopental test in epilepsy surgery patients.
Schools
University of Pittsburgh School of Medicine
Mercy Hospital
Mass Genl Hospital
Doctors Specialties
- Critical Care Medicine
- Anesthesiology
Accepted Insurances
Education
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Massachusetts General Hospital -
University of Pittsburgh Medical Center-Mercy Hospital -
University of Pittsburgh School of Medicine
Hospital
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Hospital of the University of Pennsylvania -
Pennsylvania Hospital -
Penn Presbyterian Medical Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1689616005 |
| Last Name Of The Provider | KOFKE |
| First Name Of The Provider | WILLIAM |
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