professor of medicine at University of Michigan Health System
Internal Medicine
Dr. William D. Ensminger, MD
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William Ensminger practices Internal Medicine. He researched medicine at Harvard Medical School. Harvard Medical School is one of the top medical schools in the US. Harvard Medical School is ranked 1/12 in Research/PrimaryCare. He has 1 awards "CMS Meaningful Use Stage 1 Certification". William Ensminger is also a published physician. He has 101 paper published. The most recent paper is: Treatment of intrahepatic cancers with radiation doses based on a normal tissue complication probability model.
Publications
- Phase I Trial of Dose-escalated Whole Liver Irradiation With Hepatic Arterial Fluorodeoxyuridine/Leucovorin and Streptozotocin Followed by Fluorodeoxyuridine/Leucovori...
- Low Dose Rate Radiosensitization of Hepatocellular Carcinoma In Vitro and in Patients.
- Targeting Hepatic Cancer Cells with PEGylated Dendrimers Displaying N-Acetylgalactosamine and SP94 Peptide Ligands.
- Dosimetric Analysis of Radiation-induced Gastric Bleeding.
- A Phase I Clinical and Pharmacology Study Using Amifostine as a Radioprotector in Dose-escalated Whole Liver Radiation Therapy.
- From the guest editors: introduction to local therapies in the treatment of liver Cancer.
- NCCN clinical practice guidelines in oncology: hepatobiliary Cancers.
- Hypoxia-inducible factor-1 target genes as indicators of tumor vessel response to vascular endothelial growth factor inhibition.
- Phase II trial of high-dose conformal radiation therapy with concurrent hepatic artery floxuridine for unresectable intrahepatic Malignancies.
- A role for hepatic-directed chemotherapy in coloRectal liver metastases.
- Ionizing radiation increases adenovirus uptake and improves transgene expression in intrahepatic colon Cancer xenografts.
- Regional delivery and selective expression of a high-activity yeast cytosine deaminase in an intrahepatic colon Cancer model.
- Regional pharmacokinetics of amifostine in anesthetized dogs: role of the liver, gastrointestinal Tract, lungs, and kidneys.
- Intrahepatic arterial infusion of chemotherapy: pharmacologic principles.
- Radiotherapy for pancreatic Neuroendocrine tumors.
- N-acetylgalactosamine-functionalized dendrimers as hepatic Cancer cell-targeted carriers.
- Hepatobiliary Cancers. Clinical practice guidelines in oncology.
- Effects of dexamethasone or celecoxib on Biliary toxicity after hepatic arterial infusion of 5-fluorodeoxyuridine in a canine model.
- Disposition of WR-1065 in the Liver of tumor-bearing rats following regional vs systemic administration of amifostine.
- Selective radioprotection of hepatocytes by systemic and portal vein infusions of amifostine in a rat Liver tumor model.
- Escalated focal Liver radiation and concurrent hepatic artery fluorodeoxyuridine for unresectable intrahepatic malignancies.
- New sources for accessing and interpreting electronic information.
- Interaction between gemcitabine and mitomycin-C in vitro.
- Treatment of intrahepatic Cancers with radiation doses based on a normal tissue complication probability model.
- Regional pharmacokinetics of 5-fluorouracil in dogs: role of the liver, gastrointestinal Tract, and lungs.
- A phase I trial of hepatic arterial bromodeoxyuridine and conformal radiation therapy for patients with primary hepatobiliary cancers or coloRectal liver metastases.
- Teaching skills for accessing and interpreting information from systematic reviews/meta-Analyses, practice guidelines, and the Internet.
- A phase I trial of intravenous bromodeoxyuridine and radiation therapy for pancreatic Cancer.
- Long-term results of hepatic artery fluorodeoxyuridine and conformal radiation therapy for primary hepatobiliary Cancers.
- Effect of irradiation on bromodeoxyuridine incorporation in human colon Cancer xenografts.
- Regional chemotherapy.
- Hepatic parenchymal changes after intraarterial Y-90 therapy: CT findings.
- Treatment of primary hepatobiliary Cancers with conformal radiation therapy and regional chemotherapy.
- Kinetics of bromodeoxyuridine elimination from human colon Cancer cells in vitro and in vivo.
- Clinical pharmacology of hepatic arterial infusions of 5-bromo-2'-deoxyuridine.
- Immunotherapy for Cancer by direct gene transfer into tumors.
- Mutual kinetic interaction between 5-fluorouracil and bromodeoxyuridine or iododeoxyuridine in dogs.
- Radiosensitization with carotid intra-arterial bromodeoxyuridine +/- 5-fluorouracil biomodulation for malignant gliomas.
- Hepatic radioembolization with yttrium-90 containing glass microspheres: preliminary results and clinical follow-up.
- The treatment of coloRectal liver metastases with conformal radiation therapy and regional chemotherapy.
- Hepatic toxicity resulting from Cancer treatment.
- Incorporation of 5-bromo-2'-deoxyuridine into coloRectal liver metastases and liver in patients receiving a 7-day hepatic arterial infusion.
- Thymidine arrest and synchrony of Cellular growth in vivo.
- Radionuclide angiography to predict patient response to hepatic artery chemotherapy.
- Comparison of pharmacokinetics of 5-fluorouracil and 5-fluorouracil with concurrent thymidine infusions in a Phase I trial.
- Pharmacologic studies on the dibutyl and gamma-monobutyl esters of methotrexate in the rhesus monkey.
- Ocular toxicity associated with high-dose carmustine.
- Totally implanted venous and arterial access system to replace external catheters in Cancer treatment.
- Benefit from and tolerance to continuous intrathecal infusion of morphine for intractable Cancer pain.
- High-dose doxorubicin: an exploration of the dose-response curve in human neoplasia.
- Improved regional selectivity of hepatic arterial BCNU with degradable microspheres.
- Intra-arterial BCNU chemotherapy for the treatment of malignant gliomas of the central nervous system: a preliminary report.
- Treatment of central nervous system Tumors with methotrexate.
- Totally implanted system for intravenous chemotherapy in patients with Cancer.
- Ambulatory pump infusion devices for hepatic artery infusion.
- Intra-arterial BCNU chemotherapy for treatment of malignant gliomas of the central nervous system.
- BCNU solubility and toxicity in the treatment of malignant astrocytomas.
- A totally implanted injection port system for blood sampling and chemotherapy administration.
- Regional Cancer chemotherapy.
- Constant intraperitoneal 5-fluorouracil infusion through a totally implanted system.
- Intraarterial infusion chemotherapy for head and neck Cancer using a totally implantable infusion pump.
- The use and limitations of serial plasma carcinoembryonic antigen (CEA) levels as a monitor of changing metastatic Liver tumor volume in patients receiving chemotherapy.
- Improved regional selectivity of hepatic arterial mitomycin by starch microspheres.
- Regional chemotherapy of neoplastic diseases.
- Clinical pharmacology of hepatic arterial chemotherapy.
- Surgical considerations in the management of hepatic neoplasia.
- New implantable continuous administration and bolus dose intracarotid drug deLivery system for the treatment of malignant gliomas.
- Implanted system for intraventricular drug infusion in central nervous system Tumors.
- Totally implanted drug deLivery system for hepatic arterial chemotherapy.
- Hepatic arterial streptozocin: a clinical pharmacologic study in patients with Liver tumors.
- Hepatic arterial perfusion scintigraphy with Tc-99m-MAA. Use of a totally implanted drug deLivery system.
- Hepatic arterial infusion chemotherapy for metastatic liver Cancers.
- Regional chemotherapy of coloRectal cancer metastatic to the liver.
- Quantitative hepatic arterial perfusion scintigraphy and starch microspheres in Cancer chemotherapy.
- Perfusion scintigraphy (Tc-99m MAA) during surgery for placement of chemotherapy catheter in hepatic artery: concise communication.
- Stability of Cancer chemotherapeutic agents in a totally implanted drug delivery system.
- Biochemical pharmacology in medical oncology.
- Intensive sequential chemotherapy with bleomycin, Oncovin, mitomycin C, and methotrexate followed by adriamycin, cisplatin, and cyclosphosphamide in Squamous cell canc...
- Cytokinetic evaluation of the four-drug combination of bleomycin, vincristine, mitomycin C, and methotrexate (BOMM) in cultured Burkitt's lymphoma Cells and human bone...
- Bleomycin, vincristine, and mitomycin C with or without methotrexate in the treatment of squamous cell Carcinoma.
- Definition of hepatic tumor microcirculation by single photon emission computerized tomography (SPECT).
- The step in Cellular DNA synthesis blocked by reovirus infection.
- Cellular DNA replication in viral infection.
- Stability and function of mengovirus RNA in Cell-free protein synthesis.
- Cellular DNA replication in infections with cytocidal RNA viruses.
- Inhibition of synchronized Cellular deoxyribonucleic acid synthesis during Newcastle disease virus, mengovirus, or reovirus infection.
- The step in Cellular DNA synthesis blocked by Newcastle disease or mengovirus infection.
- Cellular DNA and protein synthesis in reovirus-infected L Cells.
- Sensitive high-performance liquid chromatographic method for the determination of 5-fluorouracil in plasma.
- Atlas of hepatic arterial perfusion scintigraphy.
- Rapid gas-liquid chromatographic method for plasma verapamil level determination.
- High-performance liquid chromatographic method for the determination of bromodeoxyuridine and its major metabolite, bromouracil, in biological fluids.
- Simultaneous determination of thymine and 5-bromouracil in DNA hydrolysates using gas chromatography-mass spectrometry with selected-ion monitoring.
- Steady-state nonlinear pharmacokinetics of 5-fluorouracil during hepatic arterial and intravenous infusions in Cancer patients.
- Phase I study of hepatic arterial degradable starch microspheres and mitomycin.
- The utility of SPECT for 99mTc-MAA hepatic arterial perfusion scintigraphy.
- High-dose adriamycin combination chemotherapy for intermediate and high-grade non-Hodgkin's lymphomas.
- Thrombosis and streptokinase lysis during hepatic intraarterial chemotherapy: the value of perfusion scintigraphy.
- A dog model using an implanted system for proTracted hepatic arterial chemotherapy.
- Evaluation of focal hepatic masses: a comparative study of MRI and CT.
Schools
Harvard Medical School
Beth Israel Hospital
Sidney Farber Cancer Institute
Conditions Treated
- Anal and Rectal Cancer
- Anemia
- Bile Duct Cancer
- Carcinoma in Situ
- View All
Doctors Specialties
- Medical Oncology
- Oncology
- Internal Medicine
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
Education
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Beth Israel Deaconess Medical Center -
Harvard Medical School
Hospital
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University of Michigan Hospitals and Health Centers
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