Professor, Medicine, University of Arizona College of Medicine
Cardiology
Dr. William R. Roeske, MD
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William Roeske works in the field of Cardiology. He researched medicine at Stanford University School of Medicine. Stanford University School of Medicine is one of the top medical schools in the US. Stanford University School of Medicine is ranked 2/25 in Research/PrimaryCare. He over the years received 2 awards: "Elected Member" and "Fellow (FACC)". Dr. William R. Roeske is also published. He has 101 publications published. The lastest publication: "Taurine transport in the fetal mouse heart.' He accepts Medicare payments and is listed with Medicare.gov.
Publications
- Tachykinin NK₠receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation.
- Sustained morphine treatment augments capsaicin-evoked calcitonin gene-related peptide release from primary sensory neurons in a protein kinase A- and Raf-1-dependent ...
- Mediating delta-opioid-initiated Heart protection via the beta2-adrenergic receptor: role of the intrinsic cardiac adrenergic cell.
- Quantitative evaluation of human delta opioid receptor desensitization using the operational model of drug action.
- Postural position and neurocardiogenic Syncope in late pregnancy.
- Converging protein kinase pathways mediate adenylyl cyclase superactivation upon Chronic delta-opioid agonist treatment.
- (2S,3R) beta-methyl-2',6'-dimethyltyrosine-L-tetrahydroisoquinoline-3-carboxylic acid [(2S,3R)TMT-L-Tic-OH] is a potent, selective delta-opioid receptor antagonist in ...
- Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats.
- Functional selectivity in cannabinoid signaling.
- Sustained morphine-mediated pain sensitization and antinociceptive tolerance are blocked by intrathecal treatment with Raf-1-selective siRNA.
- Neuroendocrine properties of intrinsic cardiac adrenergic cells in fetal rat Heart.
- Noninvasive evaluation of ventricular hypertrophy in professional athletes.
- Independent expression of cardiac type I and II cyclic AMP-dependent protein kinase during murine embryogenesis and postnatal development.
- Ontogeny of mammalian Myocardial beta-adrenergic receptors.
- The regulation of muscarinic cholinergic receptors by guanine nucleotides in cardiac tissue.
- Carrier-mediated taurine uptake in the fetal mouse Heart.
- Clinical pathologic correlates in Acute myocardial infarction.
- Cardiac muscarinic cholinergic receptors. Biochemical identification and characterization.
- Characterization of a carrier-mediated transport system for taurine in the fetal mouse Heart in vitro.
- Maturation of mammalian Myocardial muscarinic cholinergic receptors.
- Factors influencing enzyme release from cultured fetal mouse Hearts deprived of oxygen and glucose.
- [Museum of Pharmacy of the Medical Academy in Cracow].
- Thermally induced myocardial preservation and necrosis in deprived fetal mouse Hearts.
- Taurine transport in the fetal mouse Heart.
- Predictive factors and mechanism of Arrhythmias and myocardial ischaemic changes in elderly patients during barium enema.
- Incidence of Arrhythmias and ST-segment changes in elderly patients during barium enema studies.
- Pharmacological characterization of a novel muscarinic partial agonist, YM796, in transfected cells expressing the m1 or m2 muscarinic receptor gene.
- Demonstration of a neurokinin A receptor subtype in transfected fibroblasts.
- Cloning of the rat M3, M4 and M5 muscarinic acetylcholine receptor genes by the polymerase chain reaction (PCR) and the pharmacological characterization of the express...
- Effects of beta-adrenergic blockade on papillary muscle function and the beta-adrenergic receptor system in noninfarcted myocardium in compensated ischemic left ventri...
- Chimeric M1/M2 muscarinic receptors: correlation of ligand selectivity and functional coupling with structural modifications.
- Neurokinin A receptors are coupled to calcium mobilization in transfected fibroblasts.
- The m2 muscarinic acetylcholine receptors are coupled to multiple signaling pathways via pertussis toxin-sensitive guanine nucleotide regulatory proteins.
- Pharmacologic comparison of selected agonists for the M1 muscarinic receptor in transfected murine fibroblast cells (B82).
- The molecular properties of the M1 muscarinic receptor and its regulation of cytosolic calcium in a eukaryotic gene expression system.
- Systemic toxic effects associated with high-dose verapamil infusion and chemotherapy administration.
- Amplification of the rat M2 muscarinic receptor gene by the polymerase chain reaction: functional expression of the M2 muscarinic receptor.
- The cloning and sequence analysis of the rat serotonin-1A receptor gene.
- Characterization of muscarinic acetylcholine receptors in human labial salivary glands.
- Decreased [3H]nitrendipine binding in the brainstem of deoxycorticosterone-NaCl Hypertensive rats.
- A cholinergic antagonist identifies a subclass of muscarinic receptors in isolated rat pancreatic acini.
- Molecular pharmacology of muscarinic receptor heterogeneity.
- Pharmacological characterization of the M1 muscarinic receptors expressed in murine fibroblast B82 cells.
- The coupling of muscarinic receptors to hydrolysis of inositol lipids in human neuroblastoma SH-SY5Y cells.
- Quantitative autoradiography of M2 muscarinic receptors in the rat brain identified by using a selective radioligand [3H]AF-DX 116.
- Identification and characterization of muscarinic receptors in cultured human pancreatic carcinoma cells.
- Lactamimides: a novel chemical class of calcium antagonists with diltiazem-like properties.
- The relationship between agonist states of the M1 muscarinic receptor and the hydrolysis of inositol lipids in transfected murine fibroblast cells (B82) expressing dif...
- Hormonal regulation of myosin heavy chain and alpha-actin gene expression in cultured fetal rat Heart myocytes.
- Identification of calcium-channel receptors in intact animals.
- Specific high-affinity [3H]Ro5-4864 Ro5-4864 benzodiazepine binding sites in the brain and periphery.
- Muscarinic cholinergic ligand binding to intact mouse pituitary tumor cells (AtT-20/D16-16) coupling with two biochemical effectors: adenylate cyclase and phosphatidyl...
- Effects of chemical sympathectomy with 6-hydroxydopamine on alpha- and beta-adrenoceptors and muscarinic cholinoceptors in rat Kidney.
- Solubilization with digitonin alters the kinetics of pirenzepine binding to muscarinic receptors from rat forebrain and Heart.
- Potent enhancement of [3H]nitrendipine binding in rat cerebral cortical and cardiac homogenates: a putative mechanism for the action of MDL 12,330A.
- Irreversible inhibition by tyrosine-directed alkylating reagents of muscarinic cholinergic receptors in membranes from rat forebrain and Heart.
- Decreased muscarinic receptor density in the aged rat brain.
- The intact human neuroblastoma cell (SH-SY5Y) exhibits high-affinity [3H]pirenzepine binding associated with hydrolysis of phosphatidylinositols.
- Himbacine recognizes a high affinity subtype of M2 muscarinic cholinergic receptors in the rat cerebral cortex.
- The cloned murine M1 muscarinic receptor is associated with the hydrolysis of phosphatidylinositols in transfected murine B82 cells.
- Muscarinic receptor-mediated hydrolysis of phosphatidylinositols in human neuroblastoma (SH-SY5Y) cells is sensitive to pertussis toxin.
- Thermodynamic analyses of pirenzepine binding to membrane-bound and solubilized muscarinic receptors from rat forebrain and Heart.
- [3H]AF-DX 116 labels subsets of muscarinic cholinergic receptors in rat brain and Heart.
- Differential regulation of M2 muscarinic receptors by guanine nucleotides in rat cerebral cortical and cardiac membranes.
- Autoradiographic localization of nicotinic receptor binding in rat brain using [3H]methylcarbamylcholine, a novel radioligand.
- [3H]pirenzepine and (-)-[3H]quinuclidinyl benzilate binding to rat cerebral cortical and cardiac muscarinic cholinergic sites. I. Characterization and regulation of ag...
- [3H]pirenzepine and (-)-[3H]quinuclidinyl benzilate binding to rat cerebral cortical and cardiac muscarinic cholinergic sites. II. Characterization and regulation of a...
- Autoradiographic localization of muscarinic agonist binding sites in the rat central nervous system with (+)-cis-[3H]methyldioxolane.
- Effects of bilateral ibotenate-induced lesions of the nucleus basalis magnocellularis upon selective cholinergic biochemical markers in the rat anterior cerebral cortex.
- Regional differences in ethylcholine mustard aziridinium ion (AF64A)-induced deficits in presynaptic cholinergic markers for the rat central nervous system.
- Differential ontogeny of putative M1 and M2 muscarinic receptor binding sites in the murine cerebral cortex and Heart.
- Functional and biochemical basis for multiple muscarinic acetylcholine receptors.
- Effect of canine cardiac nerves on Heart rate, rhythm, and pacemaker location.
- Quantitative light microscopic autoradiography of [3H]hemicholinium-3 binding sites in the rat central nervous system: a novel biochemical marker for mapping the distr...
- Polish pharmacy in Copernicus'' times.
- Musealia Pharmaceutica Polona in foreign collections.
- [Alfons Bukowski (1858-1921)].
- ["Miscellanea" from the history of German and Polish pharmacy].
- [Polish pharmaceutical weights and measures in the 19th century].
- [Cosmas and Damian in the tradition of Polish medicine and pharmacy].
- Behavior of sterols of insect muscle during homogenization and differential centrifugation.
- [Magna Charta Pharmaciae from 1240 and its influence on the development of mutual relationship between pharmacy and medicine].
- High affinity specific [3H](+)PN 200-110 binding to dihydropyridine receptors associated with calcium channels in rat cerebral cortex and Heart.
- Benzodiazepine receptor heterogeneity: possible molecular basis and functional significance.
- 3H-Flunitrazepam binding to bovine retina and the effect of GABA thereon.
- Characterization of alpha-1 adrenergic receptors in the Heart using [3H]WB4101: effect of 6-hydroxydopamine treatment.
- High affinity [3H]flunitrazepam binding: characterization, localization, and alteration in Hypertension.
- gamma-Aminobutyric acid regulation of the benzodiazepine receptor: biochemical evidence for pharmacologically different effects of benzodiazepines and propyl beta-carb...
- Responsiveness to drugs and hormones in the murine model of cardiac ontogenesis.
- beta 2-Adrenoceptors regulate induction of Myocardial ornithine decarboxylase in mice in vivo.
- Agonist radioligands for identifying functional neurotransmitter receptors. Introduction.
- Pharmacological differences between the high-affinity muscarinic agonist binding states of the rat Heart and cerebral cortex labeled with (+)-[3H]cismethyldioxolane.
- Differential regulation of putative M1/M2 muscarinic receptors: implications for different receptor-effector coupling mechanisms.
- The regulation of cardiac alpha 1-adrenergic receptors by guanine nucleotides and by muscarinic cholinergic agonists.
- The regulation of cardiac muscarinic cholinergic receptors by isoproterenol.
- Alterations in cardiac autonomic receptors following 6-hydroxydopamine treatment in rats.
- Ontogeny of mammalian cardiac alpha 1-adrenergic receptors.
- Alterations in central and peripheral adrenergic receptors in deoxycorticosterone/salt Hypertensive rats.
- Reductions in retinal gamma-aminobutyric acid (GABA) content and in [3H]flunitrazepam binding after postnatal monosodium glutamate injections in rats.
- Mathematical analysis of the kinetics of competitive inhibition in neurotransmitter receptor binding assays.
Schools
Stanford University School Of Medicine
University Hospitals Of Cleveland
University Of California San Diego Medical Center
Procedures Preformed
- Cardiac Catheterization (incl. Coronary Angiography)
- Cardiac Imaging
- Cardiac MRI (Magnetic Resonance Imaging) of Heart or Chest
- Cardiac Myocardial Perfusion Imaging
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Conditions Treated
- Angina and Acute Coronary Syndrome
- Aortic Aneurysm
- Aortic Ectasia
- Aortic Valve Disease
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Doctors Specialties
- Cardiology
Accepted Insurances
Awards
- Elected Member
- Fellow (FACC)
Education
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University of California San Diego -
Case Western Reserve University - University Hospitals -
Stanford University School of Medicine
Drug Facts
| NPI NUMBER | 1932279494 | |
| NPPES Provider LastName | ROESKE | |
| NPPES Provider FirstName | WILLIAM | |
| NPPES Provider ZIPCode | 857240001 | |
| NPPES Provider State | AZ | |
| Specialty Description | Cardiology | |
| Total Claim Count | 245.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1932279494 |
| Last Name Of The Provider | ROESKE |
| First Name Of The Provider | WILLIAM |
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