Physician
Pathology
Dr. Yuri Persidsky, MD
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Yuri Persidsky works in the field of Pathology. He went to medical school at University of Nebraska Medical Center. University of Nebraska Medical Center is a one of the best medicals schools. University of Nebraska Medical Center is ranked 60 in research and 4 in primary care medicine Yuri Persidsky is also published. He has 101 publications published. The lastest publication: "Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia.' He accepts all Medicare patients.
Publications
- Summary of the 2014 Alcohol and Immunology Research Interest Group (AIRIG) meeting.
- Activation of Cannabinoid Type Two Receptors (CB2) Diminish Inflammatory Responses in Macrophages and Brain Endothelium.
- Emerging roles of pericytes in the regulation of the neurovascular unit in health and disease.
- Poly(ADP-ribose) polymerase-1 inhibition in brain endothelium protects the blood-brain barrier under physiologic and neuroinflammatory conditions.
- Dysregulation of Claudin-5 in HIV-induced Interstitial Pneumonitis and Lung Vascular Injury. Protective Role of Peroxisome Proliferator-activated Receptor-γ.
- Selective Activation of Cannabinoid Receptor 2 in Leukocytes Suppresses Their Engagement of the Brain Endothelium and Protects the Blood-Brain Barrier.
- Cannabinoid Receptor 2: Potential Role in Immunomodulation and Neuroinflammation.
- Attenuation of HIV-1 replication in macrophages by cannabinoid receptor 2 agonists.
- Inhibition of glycogen synthase kinase 3? promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5.
- Glycogen Synthase Kinase 3β Inhibition Prevents Monocyte Migration across Brain Endothelial Cells via Rac1-GTPase Suppression and Down-Regulation of Active Integrin Co...
- Craniula: A cranial window technique for prolonged imaging of brain surface vasculature with simultaneous adjacent intracerebral injection.
- Anti-Inflammatory Effect of Targeted Delivery of SOD to Endothelium: Mechanism, Synergism with NO Donors and Protective Effects In Vitro and In Vivo.
- Model systems for assessing cognitive function: implications for HIV-1 infection and drugs of abuse.
- The regulation of alpha chemokines during HIV-1 infection and leukocyte activation: relevance for HIV-1-associated dementia.
- Mononuclear phagocyte differentiation, activation, and viral infection regulate matrix metalloproteinase expression: implications for human immunodeficiency virus type...
- HIV-1 infection: new treatment paradigms.
- Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis.
- The efficacy of potent anti-retroviral drug combinations tested in a murine model of HIV-1 encephalitis.
- Mononuclear phagocytes mediate blood-brain barrier compromise and neuronal injury during HIV-1-associated dementia.
- HIV-1 infected mononuclear phagocyte secretory products affect neuronal physiology leading to cellular demise: relevance for HIV-1-associated dementia.
- Evaluation of antiretroviral drug efficacy for HIV-1 encephalitis in SCID mice.
- Model systems for studies of leukocyte migration across the blood - brain barrier.
- The neuropathogenesis of HIV-1 infection.
- Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1 encephalitis.
- Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia.
- Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia.
- Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms.
- Protein kinase C isoforms in human aortic smooth muscle cells.
- SCID mice with HIV encephalitis develop behavioral abnormalities.
- Role of the beta-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia.
- Human immunodeficiency virus neurotropism: an analysis of viral replication and cytopathicity for divergent strains in monocytes and microglia.
- An analysis of HIV-1-associated inflammatory products in brain tissue of humans and SCID mice with HIV-1 encephalitis.
- The neuropathogenesis of the AIDS dementia complex.
- Development of laboratory and animal model systems for HIV-1 encephalitis and its associated dementia.
- The development of animal model systems for HIV-1 encephalitis and its associated dementia.
- Dexamethasone therapy worsens the neuropathology of human immunodeficiency virus type 1 encephalitis in SCID mice.
- A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis.
- Human immunodeficiency virus encephalitis in SCID mice.
- Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain.
- Morpho-functional changes of follicular dendritic cells (FDC) and lymph node structure in simian immunodeficiency virus (SIV) infection.
- A regulatory role for astrocytes in HIV-1 encephalitis. An overexpression of eicosanoids, platelet-activating factor, and tumor necrosis factor-alpha by activated HIV-...
- Signs of Kupffer cell involvement in productive simian immunodeficiency virus infection in monkey liver.
- Permissiveness of Kupffer cells for simian immunodeficiency virus (SIV) and morphological changes in the liver of rhesus monkeys at different periods of SIV infection.
- Presence of virion protein x (Vpx) of simian immunodeficiency virus SIVmac 251 in target cells in vivo.
- Morphological changes in lymph nodes and expression of VCAM1 and cytokines at the late stages of SIV-induced disease in rhesus monkeys.
- Reactions of microvascular endothelial cells to tumor necrosis factor in vivo.
- Hippocampal synaptic dysfunction in a murine model of human immunodeficiency virus type 1 encephalitis.
- HIV-1 infected immune competent mononuclear phagocytes influence the pathways to neuronal demise.
- HIV-1 infected and immune competent mononuclear phagocytes induce quantitative alterations in neuronal dendritic arbor: relevance for HIV-1-associated dementia.
- Effects of pluronic P85 on GLUT1 and MCT1 transporters in the blood-brain barrier.
- Rodent model systems for studies of HIV-1 associated dementia.
- Alcohol-induced oxidative stress in brain endothelial cells causes blood-brain barrier dysfunction.
- Ethanol-induced activation of myosin light chain kinase leads to dysfunction of tight junctions and blood-brain barrier compromise.
- Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis.
- Development of a rapid autopsy program for studies of brain immunity.
- Infections of the nervous system.
- Alcohol and HIV decrease proteasome and immunoproteasome function in macrophages: implications for impaired immune function during disease.
- Levels of human immunodeficiency virus type 1 (HIV-1) replication in macrophages determines the severity of murine HIV-1 encephalitis.
- TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia.
- Mononuclear phagocyte immunity and the neuropathogenesis of HIV-1 infection.
- Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia.
- Inhibition of long-term potentiation by interleukin-8: implications for human immunodeficiency virus-1-associated dementia.
- Murine models for human immunodeficiency virus type 1-associated dementia: the development of new treatment testing paradigms.
- Generation of cytotoxic T cells against virus-infected human brain macrophages in a murine model of HIV-1 encephalitis.
- Impaired spatial cognition and synaptic potentiation in a murine model of human immunodeficiency virus type 1 encephalitis.
- Regulation of P-glycoprotein by human immunodeficiency virus-1 in primary cultures of human fetal astrocytes.
- Stabilization of superoxide dismutase by acetyl-l-carnitine in human brain endothelium during alcohol exposure: novel protective approach.
- HIV-1 infection and alcohol abuse: neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions.
- Soybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages.
- Acetyl-L-carnitine protects neuronal function from alcohol-induced oxidative damage in the brain.
- Methamphetamine causes mitrochondrial oxidative damage in human T lymphocytes leading to functional impairment.
- Alcohol impairs interferon signaling and enhances full cycle hepatitis C virus JFH-1 infection of human hepatocytes.
- Dyad of CD40/CD40 ligand fosters neuroinflammation at the blood-brain barrier and is regulated via JNK signaling: implications for HIV-1 encephalitis.
- Establishment of primary cultures of human brain microvascular endothelial cells to provide an in vitro cellular model of the blood-brain barrier.
- Alcohol-induced interactive phosphorylation of Src and toll-like receptor regulates the secretion of inflammatory mediators by human astrocytes.
- Inhibition of glycogen synthase kinase 3beta (GSK3beta) decreases inflammatory responses in brain endothelial cells.
- Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells.
- Blocking TNF-alpha attenuates aneurysm formation in a murine model.
- Monocyte chemotactic protein-1 regulates voltage-gated K+ channels and macrophage transmigration.
- Mechanism of alcohol-induced oxidative stress and neuronal injury.
- Peroxisome proliferator-activated receptor-gamma activation suppresses HIV-1 replication in an animal model of encephalitis.
- Regulation of ABC membrane transporters in glial cells: relevance to the pharmacotherapy of brain HIV-1 infection.
- Adding fuel to the fire: methamphetamine enhances HIV infection.
- Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses Rho GTPases in human brain microvascular endothelial cells and inhibits adhesion ...
- Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells.
- Battle of animal models.
- NeuroAIDS, drug abuse, and inflammation: building collaborative research activities.
- Blood-brain barrier: structural components and function under physiologic and pathologic conditions.
- STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier.
- T cell independent mechanism for copolymer-1-induced neuroprotection.
- Activation of protein tyrosine kinases and matrix metalloproteinases causes blood-brain barrier injury: Novel mechanism for neurodegeneration associated with alcohol a...
- HIV-1 activates proinflammatory and interferon-inducible genes in human brain microvascular endothelial cells: putative mechanisms of blood-brain barrier dysfunction.
- HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: new insights into blood-brain barrier dysfunction for HIV-1...
- Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction.
- Alcohol-induced blood-brain barrier dysfunction is mediated via inositol 1,4,5-triphosphate receptor (IP3R)-gated intracellular calcium release.
- HIV-1 neuropathogenesis: glial mechanisms revealed through substance abuse.
- Novel delivery system enhances efficacy of antiretroviral therapy in animal model for HIV-1 encephalitis.
- Immune privilege and HIV-1 persistence in the CNS.
- HIV-1 gp120 compromises blood-brain barrier integrity and enhances monocyte migration across blood-brain barrier: implication for viral neuropathogenesis.
- Alcohol abuse enhances neuroinflammation and impairs immune responses in an animal model of human immunodeficiency virus-1 encephalitis.
Doctors Specialties
- Anatomic Pathology
- Pathology
Accepted Insurances
- Amerihealth
- HealthPartners
- Humana
- Medicare MCR
- United Healthcare
Education
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University of Nebraska Medical Center -
National Medical University Kiev
Hospital
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Temple University Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1437109659 |
| Last Name Of The Provider | PERSIDSKY |
| First Name Of The Provider | YURI |
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